2019
Follow-Up of Patients With Ulcerative Colitis and Histological Normalization
Israel A, Christensen B, El Jurdi K, Rai V, Ollech J, Cohen R, Sakuraba A, Dalal S, Rubin D. Follow-Up of Patients With Ulcerative Colitis and Histological Normalization. Clinical Gastroenterology And Hepatology 2019, 18: 987-988.e1. PMID: 31228567, PMCID: PMC6923607, DOI: 10.1016/j.cgh.2019.06.025.Peer-Reviewed Original ResearchConceptsUlcerative colitisManagement of UCSpecific treatment goalsEndoscopic improvementHistological normalizationDisease activityMucosal injuryRemitting courseHistological endpointsTreatment goalsNatural historyColitisMicroscopic featuresUnanswered questionsInflammationPatientsChronicityMucosaInjuryHistologyDiagnosisEndpointLevamisole in Children with Idiopathic Nephrotic Syndrome: Clinical Efficacy and Pathophysiological Aspects
Mühlig A, Lee J, Kemper M, Kronbichler A, Yang J, Lee J, Shin J, Oh J. Levamisole in Children with Idiopathic Nephrotic Syndrome: Clinical Efficacy and Pathophysiological Aspects. Journal Of Clinical Medicine 2019, 8: 860. PMID: 31208104, PMCID: PMC6617114, DOI: 10.3390/jcm8060860.Peer-Reviewed Original ResearchIdiopathic nephrotic syndromeNephrotic syndromeRandomized Controlled TrialsLow frequency of side effectsSteroid-dependent nephrotic syndromeSteroid-sensitive nephrotic syndromeFrequency of side effectsSteroid-sensitive formsSynthetic imidazothiazole derivativeRelapsing nephrotic syndromeImmune-modulatory propertiesPediatric glomerular diseasesSteroid toxicitySteroid therapyMycophenolate mofetilSteroid-dependentRelapse rateRelapse riskFrequent relapsesClinical efficacyReview recent dataExpensive therapyRemitting courseRelapseRandomized trials
2018
A review of cutaneous manifestations within glucagonoma syndrome: necrolytic migratory erythema
Tolliver S, Graham J, Kaffenberger B. A review of cutaneous manifestations within glucagonoma syndrome: necrolytic migratory erythema. International Journal Of Dermatology 2018, 57: 642-645. PMID: 29450880, DOI: 10.1111/ijd.13947.Peer-Reviewed Original ResearchConceptsNecrolytic migratory erythemaMigratory erythemaGlucagonoma syndromeCutaneous manifestationsLong-acting somatostatin analog octreotidePancreatic tumor stagingSomatostatin analog octreotideConsistent with necrolytic migratory erythemaRare skin disorderSuperficial epidermal necrosisOctreotide treatmentAnalog octreotideTumor stagePancreatic tumorsClinical presentationAnnular eruptionPancreatic glucagonomaRare caseIntertriginous areasClinical examinationRemitting courseErythematous papulesPlaque-likeGlucagonomaSkin symptoms
2016
The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample
Oedegaard K, Alda M, Anand A, Andreassen O, Balaraman Y, Berrettini W, Bhattacharjee A, Brennand K, Burdick K, Calabrese J, Calkin C, Claasen A, Coryell W, Craig D, DeModena A, Frye M, Gage F, Gao K, Garnham J, Gershon E, Jakobsen P, Leckband S, McCarthy M, McInnis M, Maihofer A, Mertens J, Morken G, Nievergelt C, Nurnberger J, Pham S, Schoeyen H, Shekhtman T, Shilling P, Szelinger S, Tarwater B, Yao J, Zandi P, Kelsoe J. The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample. BMC Psychiatry 2016, 16: 129. PMID: 27150464, PMCID: PMC4857276, DOI: 10.1186/s12888-016-0732-x.Peer-Reviewed Original ResearchConceptsLithium monotherapyBipolar disorderLithium responseMechanism of actionClinical managementValproic acidLithium respondersSingle nucleotide polymorphismsMethods/designThis studyCox proportional hazards modelProspective study sampleLarge prospective cohortLarge prospective studiesClinical Global ImpressionInitiation of treatmentMood-stabilizing medicationsBipolar Disorder (STEP-BD) studyProportional hazards modelResults of treatmentCommon psychiatric disordersMEq/L.Genome-wide association studiesClinical relapseProspective cohortRemitting course
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