2024
Predicting remission following CBT for childhood anxiety disorders: a machine learning approach
Bertie L, Quiroz J, Berkovsky S, Arendt K, Bögels S, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Fjermestadt K, In-Albon T, Lavallee K, Lester K, Lyneham H, Marin C, McKinnon A, McLellan L, Meiser-Stedman R, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Wuthrich V, Hudson J. Predicting remission following CBT for childhood anxiety disorders: a machine learning approach. Psychological Medicine 2024, 54: 4612-4622. PMID: 39686883, DOI: 10.1017/s0033291724002654.Peer-Reviewed Original ResearchAnxiety disordersIdentification of predictors of treatment responseComorbid externalising disordersMultiple anxiety disordersPrimary anxiety disorderRisk of non-remissionChildhood anxiety disordersSocial anxiety disorderPredictors of treatment responseLikelihood of remissionHigher likelihood of remissionAnxious youthChildhood anxietyDisorder remissionComorbid depressionExternalising disordersGroup treatmentDepressive symptomsHigher anxietyImprove treatment outcomesPredicting remissionNon-remissionAnxietyRemission outcomesDisordersPatients with ulcerative colitis who have normalized histology are clinically stable after de-escalation of therapy
Akiyama S, St-Pierre J, Traboulsi C, Silfen A, Rai V, Rodriguez T, Erondu A, Steinberg J, Shaffer S, Christensen B, Rubin D. Patients with ulcerative colitis who have normalized histology are clinically stable after de-escalation of therapy. Npj Gut And Liver 2024, 1: 5. DOI: 10.1038/s44355-024-00005-9.Peer-Reviewed Original ResearchHistologic normalizationUlcerative colitisDe-EscalationUC patientsDe-escalation of therapyTherapeutic de-escalationMedian Follow-UpDe-escalation groupProportion of patientsStudy assessed outcomesHistological recurrenceRecurrence rateSingle-centerClinical stabilityTherapeutic changeRemission outcomesFollow-upTherapyPatientsImmunomodulationAminosalicylatesWithdrawalColitisMonthsOutcomes
2023
Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: Analysis of the REDES study
Pavord I, Gardiner F, Heaney L, Domingo C, Price R, Pullan A, Oppenheimer J, Brusselle G, Nagase H, Chupp G, Pizzichini E, Bañas-Conejero D, Howarth P. Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: Analysis of the REDES study. Frontiers In Immunology 2023, 14: 1150162. PMID: 37122713, PMCID: PMC10131245, DOI: 10.3389/fimmu.2023.1150162.Peer-Reviewed Original ResearchConceptsSevere eosinophilic asthmaClinical remissionEosinophilic asthmaRemission definitionsClinical practiceAsthma Control Test scoresBetter ACT scoresProportion of patientsSubset of patientsACT scoreMepolizumab therapyMepolizumab treatmentOral corticosteroidsPrior exacerbationsOC useSevere asthmaBaseline characteristicsExpiratory volumeLung functionRemission outcomesMedical recordsDisease progressionTreatment outcomesRemissionTreatment goals
2011
A randomized controlled trial for obesity and binge eating disorder: Low-energy-density dietary counseling and cognitive-behavioral therapy
Masheb RM, Grilo CM, Rolls BJ. A randomized controlled trial for obesity and binge eating disorder: Low-energy-density dietary counseling and cognitive-behavioral therapy. Behaviour Research And Therapy 2011, 49: 821-829. PMID: 22005587, PMCID: PMC3223390, DOI: 10.1016/j.brat.2011.09.006.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyWeight lossDietary counselingVegetable consumptionPercent of participantsBinge remissionObese patientsRemission outcomesNutrition counselingMetabolic outcomesObese individualsConsecutive participantsFavorable outcomeDietary outcomesTwelve-monthBetter dietary outcomesDensity dietIndividual treatmentTreatment effectsOutcomesTherapyCounselingTreatmentBingeDisorders
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