Tension-dependent regulation of mammalian Hippo signaling through LIMD1
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. Journal Of Cell Science 2018, 131: jcs214700. PMID: 29440237, PMCID: PMC5897721, DOI: 10.1242/jcs.214700.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdherens JunctionsAnimalsCarrier ProteinsCell CountCell ProliferationCo-Repressor ProteinsCytoskeletal ProteinsCytoskeletonDogsHEK293 CellsHippo Signaling PathwayHumansIntracellular Signaling Peptides and ProteinsLIM Domain ProteinsMechanotransduction, CellularPhosphoproteinsProtein Serine-Threonine Kinasesrho-Associated KinasesSignal TransductionTranscription FactorsTumor Suppressor ProteinsYAP-Signaling ProteinsConceptsMammalian Hippo signalingHippo signalingLATS kinasesFamily proteinsRegulation of Lats kinasesLocalization to adherens junctionsRegulation of Hippo signalingJunctional localizationDensity-dependent regulationRho-mediatedRho activationAdherens junctionsAjubaLIMD1Biomechanical cuesKinaseJunctional complexesRhoCell densityProteinPathwayRegulationWTIPCytoskeletonSignal
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