IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids
Malla A, Bhandari R. IP6K1 is essential for chromatoid body formation and temporal regulation of Tnp2 and Prm2 expression in mouse spermatids. Journal Of Cell Science 2017, 130: 2854-2866. PMID: 28743739, DOI: 10.1242/jcs.204966.Peer-Reviewed Original ResearchConceptsRound spermatidsTemporal regulationMale germ cell differentiationDeletion of IP6K1Associated First Person interviewGerm cell differentiationRNA-binding proteinsInositol hexakisphosphate kinasesFirst Person interviewRegulate several physiological processesSomatic histonesSpermatid differentiationSpermatid elongationMouse testisPachytene spermatocytesMouse spermatidsChromatoid bodyChromatin componentsPRM2 expressionTranslational derepressionSpermatidsAberrant localisationIP6K1Body formationPremature expression
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