2018
Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM). Light: Science & Applications 2018, 7: 9. PMID: 29963322, PMCID: PMC6020849, DOI: 10.1038/s41377-018-0001-5.Peer-Reviewed Original ResearchFocal adhesion dynamicsFocal adhesion areaFocal adhesion formationPhotonic crystal biosensorCell surface contactFocal adhesionsReflection peak intensityAdhesion dynamicsRegulate adhesionCell membrane componentsCell-surface interactionsLabel-free modalityEvanescent fieldMembrane componentsLabel-free approachMigration speedPeak intensityCluster dimensionCell interactionsQuantitative imagingBasement membraneAdhesion areaEpithelial stem cellsPhotonsCells
2016
Quantitative imaging of cell membrane-associated effective mass density using Photonic Crystal Enhanced Microscopy (PCEM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Quantitative imaging of cell membrane-associated effective mass density using Photonic Crystal Enhanced Microscopy (PCEM). Progress In Quantum Electronics 2016, 50: 1-18. PMID: 28649149, PMCID: PMC5479321, DOI: 10.1016/j.pquantelec.2016.10.001.Peer-Reviewed Original ResearchTight spatial confinementNarrow resonance peakEffective mass densityLabel-free live cell imagingAxial spatial resolutionPhotonic crystal biosensorPlasma membraneResonance peakMass densityEvanescent fieldSpatial confinementCell adhesionPhenotype of single cellsLight sourcesSpatial resolutionNon-coherent light sourceLive cell imagingComplex spatiotemporal informationCellular materialCellular processesQuantitative imagingMechanical propertiesCell surface interfaceMigration eventsMatrix material