2020
Water and lipid suppression techniques for advanced 1H MRS and MRSI of the human brain: Experts' consensus recommendations
Tkáč I, Deelchand D, Dreher W, Hetherington H, Kreis R, Kumaragamage C, Považan M, Spielman DM, Strasser B, de Graaf R. Water and lipid suppression techniques for advanced 1H MRS and MRSI of the human brain: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4459. PMID: 33327042, PMCID: PMC8569948, DOI: 10.1002/nbm.4459.Peer-Reviewed Original ResearchContribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations
Cudalbu C, Behar KL, Bhattacharyya PK, Bogner W, Borbath T, de Graaf R, Gruetter R, Henning A, Juchem C, Kreis R, Lee P, Lei H, Marjańska M, Mekle R, Murali‐Manohar S, Považan M, Rackayová V, Simicic D, Slotboom J, Soher BJ, Starčuk Z, Starčuková J, Tkáč I, Williams S, Wilson M, Wright AM, Xin L, Mlynárik V. Contribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4393. PMID: 33236818, PMCID: PMC10072289, DOI: 10.1002/nbm.4393.Peer-Reviewed Original ResearchECLIPSE utilizing gradient‐modulated offset‐independent adiabaticity (GOIA) pulses for highly selective human brain proton MRSI
Kumaragamage C, De Feyter HM, Brown P, McIntyre S, Nixon TW, de Graaf R. ECLIPSE utilizing gradient‐modulated offset‐independent adiabaticity (GOIA) pulses for highly selective human brain proton MRSI. NMR In Biomedicine 2020, 34: e4415. PMID: 33001485, PMCID: PMC9472321, DOI: 10.1002/nbm.4415.Peer-Reviewed Original Research
2018
Elliptical localization with pulsed second‐order fields (ECLIPSE) for robust lipid suppression in proton MRSI
de Graaf R, Brown PB, De Feyter HM, McIntyre S, Nixon TW. Elliptical localization with pulsed second‐order fields (ECLIPSE) for robust lipid suppression in proton MRSI. NMR In Biomedicine 2018, 31: e3949. PMID: 29985532, PMCID: PMC6108906, DOI: 10.1002/nbm.3949.Peer-Reviewed Original Research
2017
Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing
Lindeboom L, de Graaf R. Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing. Magnetic Resonance In Medicine 2017, 79: 619-627. PMID: 28474367, DOI: 10.1002/mrm.26740.Peer-Reviewed Original ResearchConceptsAdipose tissueProton magnetic resonance spectroscopySkeletal muscleH-MRSAccumulation of triglyceridesInvasive biopsyMetabolic derangementsEctopic fatInsulin resistanceCardiovascular diseaseMetabolic diseasesMEGA-sLASER sequenceIn vivoNonadipose tissuesLipid resonancesSpectral editingPolyunsaturated fatty acidsHuman skeletal muscleMagnetic resonance spectroscopyLipid storesLipid compositionAdiposeSpectral resolutionTissuePhantom experiments
2013
Intramolecular zero‐quantum‐coherence 2D NMR spectroscopy of lipids in the human breast at 7 T
de Graaf R, Klomp D, Luijten P, Boer V. Intramolecular zero‐quantum‐coherence 2D NMR spectroscopy of lipids in the human breast at 7 T. Magnetic Resonance In Medicine 2013, 71: 451-457. PMID: 23468435, DOI: 10.1002/mrm.24701.Peer-Reviewed Original ResearchConceptsMagnetic field homogeneityZero-quantum coherencesMagnetic field inhomogeneityField homogeneityField inhomogeneityNavigator echo correctionHuman breastEcho correctionSusceptible boundariesSpectra in vivoHuman breast tissueLipid profileInhomogeneityBreast tissueBreastIn vivoIn vitroLipid signalingSpectraNMR spectraMRSSubjectsNMR