2023
Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb
James S, Sanggaard S, Akif A, Mishra S, Sanganahalli B, Blumenfeld H, Verhagen J, Hyder F, Herman P. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb. Cerebrovascular And Brain Metabolism Reviews 2023, 43: 1891-1904. PMID: 37340791, PMCID: PMC10676132, DOI: 10.1177/0271678x231183887.Peer-Reviewed Original ResearchConceptsVasodilatory responseCerebral cortexNeurovascular couplingOlfactory bulbNeuronal activityBrief sensory stimuliRegional neurovascular couplingStimulus-induced activityHypercapnia challengeVascular toneNeuronal deactivationHemodynamic responseNeuronal excitabilityNeuronal responsesCalcium transientsBrain functionHemodynamic signalsSensory stimuliVasodilationHypercapniaCortexMiceCareful appraisalStimuliMetabolic waste
2001
NO Synthase Blockade Induces Chaotic Cerebral Vasomotion via Activation of Thromboxane Receptors
Lacza Z, Hermán P, Görlach C, Hortobágyi T, Sándor P, Wahl M, Benyó Z. NO Synthase Blockade Induces Chaotic Cerebral Vasomotion via Activation of Thromboxane Receptors. Stroke 2001, 32: 2609-2614. PMID: 11692025, DOI: 10.1161/hs1101.098526.Peer-Reviewed Original ResearchConceptsThromboxane receptorL-NACerebral vasomotionThromboxane receptor agonist URat middle cerebral arteriesIntact vesselsGuanylyl cyclase inhibitor 1HNitro-L-arginineMiddle cerebral arteryNO-cGMP pathwayNO donor sodium nitroprussideDonor sodium nitroprussideLack of NOSignificant vasomotionUTP administrationEndothelial dysfunctionSynthase blockadeAgonist UCerebral arteryVascular tensionCerebrovascular diseaseVascular toneCerebral vesselsSynthase inhibitionSodium nitroprusside