2013
Cocaine Cue-Induced Dopamine Release in Amygdala and Hippocampus: A High-Resolution PET [18F]Fallypride Study in Cocaine Dependent Participants
Fotros A, Casey K, Larcher K, Verhaeghe J, Cox S, Gravel P, Reader A, Dagher A, Benkelfat C, Leyton M. Cocaine Cue-Induced Dopamine Release in Amygdala and Hippocampus: A High-Resolution PET [18F]Fallypride Study in Cocaine Dependent Participants. Neuropsychopharmacology 2013, 38: 1780-1788. PMID: 23546387, PMCID: PMC3717549, DOI: 10.1038/npp.2013.77.Peer-Reviewed Original ResearchConceptsDA releaseDopamine releaseVisual analog scaleDrug cue exposureCocaine-dependent volunteersDrug-seeking behaviorCocaine-dependent participantsAnalog scaleDrug-related cuesLimbic networkAnimal studiesCocaine dependenceHippocampusCue exposureAmygdalaPreferential inductionBPND valuesPotent triggerStriatumDependent participantsCocaine cuesReward networkSubjective responsesNeutral cuesFirst evidence
2007
In vivo measurements of brain trapping of C-labelled alpha-methyl-L-tryptophan during acute changes in mood states.
Perreau-Linck E, Beauregard M, Gravel P, Paquette V, Soucy J, Diksic M, Benkelfat C. In vivo measurements of brain trapping of C-labelled alpha-methyl-L-tryptophan during acute changes in mood states. Journal Of Psychiatry And Neuroscience 2007, 32: 430-4. PMID: 18043767, PMCID: PMC2077345.Peer-Reviewed Original ResearchConceptsPositron emission tomographyBrain trappingEmotional statesRight anterior cingulate cortexNeutral emotional stateNeurobiology of emotionAnterior cingulate cortexWhole-brain analysisSubjects repeated-measures designState-related changesAcute changesL-tryptophanAutobiographical memoryRepeated-measures designHealthy peopleCingulate cortexBrain Imaging CenterEmission tomographyMood statesMcConnell Brain Imaging CentreBrain analysisNormal moodExperienced levelScan acquisitionSustained changes
2006
Acute prefrontal cortex TMS in healthy volunteers: Effects on brain 11C-αMtrp trapping
Sibon I, Strafella A, Gravel P, Ko J, Booij L, Soucy J, Leyton M, Diksic M, Benkelfat C. Acute prefrontal cortex TMS in healthy volunteers: Effects on brain 11C-αMtrp trapping. NeuroImage 2006, 34: 1658-1664. PMID: 17188517, DOI: 10.1016/j.neuroimage.2006.08.059.Peer-Reviewed Original ResearchConceptsRepetitive transcranial magnetic stimulationLeft dorsolateral prefrontal cortexAcute repetitive transcranial magnetic stimulationLeft occipital cortexHealthy volunteersLimbic areasMajor depressionHigh-frequency repetitive transcranial magnetic stimulationHz repetitive transcranial magnetic stimulationPrefrontal repetitive transcranial magnetic stimulationRight cingulate gyrusSerotonin synthesis capacityTranscranial magnetic stimulationAutonomic measuresLeft parahippocampal gyrusDorsolateral prefrontal cortexMechanism of actionRTMS sessionsBrain uptakeRandomized counterbalanced orderCingulate gyrusRight insulaOccipital cortexMagnetic stimulationParahippocampal gyrus