2016
Cocaine cue–induced dopamine release in the human prefrontal cortex
Milella M, Fotros A, Gravel P, Casey K, Larcher K, Verhaeghe J, Cox S, Reader A, Dagher A, Benkelfat C, Leyton M. Cocaine cue–induced dopamine release in the human prefrontal cortex. Journal Of Psychiatry And Neuroscience 2016, 41: 322-330. PMID: 26900792, PMCID: PMC5008921, DOI: 10.1503/jpn.150207.Peer-Reviewed Original ResearchMeSH KeywordsAdultBenzamidesBrain MappingCocaineCocaine-Related DisordersCorpus StriatumCravingCuesDopamineDopamine D2 Receptor AntagonistsDopamine Uptake InhibitorsFemaleFluorine RadioisotopesHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsPositron-Emission TomographyPrefrontal CortexRadiopharmaceuticalsConceptsDA releaseMedial orbitofrontal cortexPrefrontal cortexDrug-related cuesDopamine releaseHuman prefrontal cortexOrbitofrontal cortexCortical DA releasePresence of autoreceptorsDA cell bodiesD2 receptor levelsD2/3 receptor availabilityCurrent cocaine dependencePositron emission tomographyCocaine use disorderDorsolateral prefrontal cortexSelf-reported cravingStriatal changesHigh-resolution positron emission tomographyReceptor levelsSeparate regulatory mechanismsStriatal regionsDA responseUse disordersReceptor availability
2012
GABAA receptors in visual and auditory cortex and neural activity changes during basic visual stimulation
Qin P, Duncan N, Wiebking C, Gravel P, Lyttelton O, Hayes D, Verhaeghe J, Kostikov A, Schirrmacher R, Reader A, Northoff G. GABAA receptors in visual and auditory cortex and neural activity changes during basic visual stimulation. Frontiers In Human Neuroscience 2012, 6: 337. PMID: 23293594, PMCID: PMC3533380, DOI: 10.3389/fnhum.2012.00337.Peer-Reviewed Original ResearchAuditory cortexFunctional connectivityVisual cortexInter-regional functional connectivityNeural activityNeural activity changesBrain activityLocal brain activityStimulus-induced activityVisual stimuliRecent imaging studiesEyes-open stateHaemodynamic responseGABA systemΓ-aminobutyric acidGABAA receptorsReceptor levelsGABA concentrationImaging studiesCortexVisual stimulationReceptorsSimple visual stimuliDiscrete visual stimulusClosed eyes