2017
Use of Monte Carlo Techniques in Nuclear Medicine
Fahey F, Grogg K, Fakhri G. Use of Monte Carlo Techniques in Nuclear Medicine. Journal Of The American College Of Radiology 2017, 15: 446-448. PMID: 29173989, PMCID: PMC6335966, DOI: 10.1016/j.jacr.2017.09.045.Peer-Reviewed Original ResearchFeasibility study of using fall‐off gradients of early and late PET scans for proton range verification
Cho J, Grogg K, Min C, Zhu X, Paganetti H, Lee H, Fakhri G. Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification. Medical Physics 2017, 44: 1734-1746. PMID: 28273345, PMCID: PMC5462437, DOI: 10.1002/mp.12191.Peer-Reviewed Original ResearchMeSH KeywordsFeasibility StudiesHumansMonte Carlo MethodPhantoms, ImagingPositron-Emission TomographyProtonsConceptsProton range verificationProton rangeMonte Carlo simulationsRange verificationFall-offIn-room positron emission tomographyCarlo simulationsResidual proton rangeDose fall-offPostirradiation delayPositron emission tomography imagingSOBP beamProton beamPositron emission tomographyPositron emission tomography scanPhantom studyIn-roomFunction of depthPhantomProtonOff-setMonteAcquisition timeBeamPositron emission tomography signal
2015
Mapping 15O Production Rate for Proton Therapy Verification
Grogg K, Alpert N, Zhu X, Min C, Testa M, Winey B, Normandin M, Shih H, Paganetti H, Bortfeld T, Fakhri G. Mapping 15O Production Rate for Proton Therapy Verification. International Journal Of Radiation Oncology • Biology • Physics 2015, 92: 453-459. PMID: 25817530, PMCID: PMC4431894, DOI: 10.1016/j.ijrobp.2015.01.023.Peer-Reviewed Original ResearchConceptsDecay constantProton treatment planningMonte Carlo predictionsProton therapyPhantom materialTreatment deliveryPhantomThigh activityPositron emission tomographyProduction rateDynamic PET measurementsTreatment planningRabbit thigh muscleClearance rateProtonIsotopesChanges due to therapyRadionuclide speciesOxygen-15ConstantDecayImaging targetsMontePositronEffects of perfusion
2013
Clinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy
Min C, Zhu X, Winey B, Grogg K, Testa M, Fakhri G, Bortfeld T, Paganetti H, Shih H. Clinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2013, 86: 183-189. PMID: 23391817, PMCID: PMC3640852, DOI: 10.1016/j.ijrobp.2012.12.010.Peer-Reviewed Original ResearchConceptsIn-room positron emission tomographyProton therapyIn-roomPositron emission tomography scanIn-room PET scannerPassive scattering proton therapyShapes of target volumesPositron emission tomographyMC predictionBeam range uncertaintiesMeasured PET imagesMonte CarloProton radiation therapyLocal elemental compositionBiological washoutScan timeTreatment headTreatment verificationRange uncertaintiesTarget volumePET scan timePET scannerPET systemComputed tomographyMC results