2024
Enlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders.
Guimond S, Alftieh A, Devenyi G, Mike L, Chakravarty M, Shah J, Parker D, Sweeney J, Pearlson G, Clementz B, Tamminga C, Keshavan M. Enlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders. Psychological Medicine 2024, 54: 1835-1843. PMID: 38357733, PMCID: PMC11132920, DOI: 10.1017/s003329172300380x.Peer-Reviewed Original ResearchPituitary gland volumePsychotic disordersSymptom severityAntipsychotic doseIllness durationCognitive functionAssociated with greater symptom severitySignificant effect of diagnosisAssociated with symptom severityHigher antipsychotic dosePituitary volumeBipolar-Schizophrenia NetworkIntermediate Phenotypes consortiumStructural magnetic resonance imagingProgression of psychosisGreater symptom severityEffect of diagnosisLower cognitive functionMore severe symptomsSample of individualsTransdiagnostic sampleMAGeT Brain algorithmGland volumeTrait markerBetween-group differences
2018
T22. PITUITARY GLAND VOLUME DIFFERENCES IN INDIVIDUALS WITH PSYCHOSIS: RESULTS FROM THE BIPOLAR-SCHIZOPHRENIA NETWORK ON INTERMEDIATE PHENOTYPES (B-SNIP) STUDY
Guimond S, Tingue S, Devenyi G, Tang Y, Mike L, Chakravarty M, Sweeney J, Pearlson G, Clementz B, Tamminga C, Keshavan M. T22. PITUITARY GLAND VOLUME DIFFERENCES IN INDIVIDUALS WITH PSYCHOSIS: RESULTS FROM THE BIPOLAR-SCHIZOPHRENIA NETWORK ON INTERMEDIATE PHENOTYPES (B-SNIP) STUDY. Schizophrenia Bulletin 2018, 44: s121-s121. PMCID: PMC5888564, DOI: 10.1093/schbul/sby016.298.Peer-Reviewed Original ResearchPituitary gland volumeLarger pituitary glandsDuration of illnessHealthy controlsGland volumePituitary glandPsychotic bipolar disorderSymptom severityBipolar-Schizophrenia NetworkPituitary volumeSchizoaffective disorderLarger pituitary gland volumesClinical diagnosisLarger pituitary volumeSubgroup of patientsSignificant main effectGreater symptom severitySignificant subgroup differencesIndependent t-testAdrenal axisPatient groupIntermediate Phenotypes (B-SNIP) consortiumMAGeT Brain algorithmStructural magnetic resonance imagesIntermediate Phenotypes (B-SNIP) study