2023
Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis
Lizano P, Kiely C, Mijalkov M, Meda S, Keedy S, Hoang D, Zeng V, Lutz O, Pereira J, Ivleva E, Volpe G, Xu Y, Lee A, Rubin L, Hill S, Clementz B, Tamminga C, Pearlson G, Sweeney J, Gershon E, Keshavan M, Bishop J. Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis. Brain Behavior And Immunity 2023, 114: 3-15. PMID: 37506949, PMCID: PMC10592140, DOI: 10.1016/j.bbi.2023.07.014.Peer-Reviewed Original ResearchConceptsResting-state networksHealthy controlsInter-network connectivityWorse verbal fluencyAnterior default mode networkC-reactive proteinResting-state functional networksDefault mode network connectivityRight frontoparietal networkMode network connectivityWorse cognitive performanceResting-state fMRIDefault mode networkFunctional network topologyInflammatory signatureSystemic inflammationInflammatory subgroupIL-6Neuroanatomical alterationsPsychosis probandsCo-activation patternsPsychosis spectrum disordersNetwork dysfunctionMultiple comparison correctionClinical implications
2022
Acute cannabis-related alterations in an fMRI time estimation task
Patel K, Stevens M, Adhikari S, Book G, Mubeen M, Pearlson G. Acute cannabis-related alterations in an fMRI time estimation task. 2022 DOI: 10.26828/cannabis.2022.02.000.26.Peer-Reviewed Original ResearchMedial temporal cortexPosterior cingulate cortexSomatosensory motor cortexPremotor cortexMotor cortexTemporal cortexMedial prefrontal cortexCingulate cortexFrontal cortexLong-duration stimuliAnterior cingulateInferior frontal cortexVisual cortexBrain activation differencesMultiple comparison correctionPlacebo conditionActivation differencesDuration stimuliPrefrontal cortexVisual areasOccipital junctionDose-related mannerMid-cingulate cortexSignificant activation differencesPopular recreational drug