2024
Categorical and Dimensional Approaches for Psychiatric Classification and Treatment Targeting: Considerations from Psychosis Biotypes
Clementz B, Assaf M, Sweeney J, Gershon E, Keedy S, Hill S, Ivleva E, Tamminga C, McDowell J, Keshavan M, Gibbons R, Carpenter W, Pearlson G. Categorical and Dimensional Approaches for Psychiatric Classification and Treatment Targeting: Considerations from Psychosis Biotypes. Advances In Neurobiology 2024, 40: 685-723. PMID: 39562461, DOI: 10.1007/978-3-031-69491-2_23.Peer-Reviewed Original ResearchConceptsIdiopathic psychosisBiotype-1Response to clozapineBipolar-Schizophrenia NetworkContinuum of severityReduced physiological responseDSM diagnosesNeurobiological distinctionsCategorical diagnosisSchizophrenia NetworkDiagnostic boundariesSalient stimuliPsychosis diagnosisPsychosis casesPsychiatric classificationPsychosis dataPsychosisBiotype-2Identified biotypesNeural activityIntermediate phenotypesTreatment targetElectrophysiological biomarkersElectrophysiological measurementsMedical model
2021
Anterior Default Mode Network Mediates the Relationship Between Systemic Inflammation and Cognition in Idiopathic Psychosis
Lizano P, Keedy S, Meda S, Hill K, Lee A, Lutz O, Rubin L, Tamminga C, Clementz B, Pearlson G, Gershon E, Sweeney J, Keshavan M, Bishop J. Anterior Default Mode Network Mediates the Relationship Between Systemic Inflammation and Cognition in Idiopathic Psychosis. Biological Psychiatry 2021, 89: s259. DOI: 10.1016/j.biopsych.2021.02.648.Peer-Reviewed Original Research