2019
Intrinsic neural activity differences in psychosis biotypes: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium
Thomas O, Parker D, Trotti R, McDowell J, Gershon E, Sweeney J, Keshavan M, Keedy S, Ivleva E, Tamminga C, Pearlson G, Clementz B. Intrinsic neural activity differences in psychosis biotypes: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium. Biomarkers In Neuropsychiatry 2019, 1: 100002. PMID: 36643612, PMCID: PMC9837786, DOI: 10.1016/j.bionps.2019.100002.Peer-Reviewed Original ResearchPsychosis biotypesHealthy personsBipolar-Schizophrenia NetworkSingle-trial powerFirst-degree biological relativesNeural activity differencesInter-stimulus intervalBiotype 2Intermediate Phenotypes (B-SNIP) consortiumPsychosis casesEffective treatmentIntrinsic activityPsychosis subgroupsNeural modulationLow intrinsic activityDSM groupNeural activitySocial functioningBiotype characterizationBiological relativesConventional diagnosisIntermediate phenotypesDifferentiating featuresDSM syndromesProbands
2017
5.3 Endophenotypes Guide Psychosis Neurobiology Formulations
Tamminga C, Clementz B, Keshavan M, Gershon E, Pearlson G, Ivleva E. 5.3 Endophenotypes Guide Psychosis Neurobiology Formulations. Schizophrenia Bulletin 2017, 43: s7-s7. DOI: 10.1093/schbul/sbx021.019.Peer-Reviewed Original ResearchConventional diagnosisFunctional brain biomarkersBiomarker compositesGray matter changesPsychosis researchHealthy controlsAdditional biomarkersClear pathophysiologyBrain biomarkersMatter changesAxis IProband groupsBiotype 1Higher negative symptomsLifetime ratesPsychiatric conditionsNegative symptomsPsychosis groupPsychotic conditionsSchizophrenia NetworkDistinct molecular markersDiagnosisAdolescent cannabisBiomarkersEEG characteristics