2017
Joint estimation of activity image and attenuation sinogram using time-of-flight positron emission tomography data consistency condition filtering
Li Q, Li H, Kim K, Fakhri G. Joint estimation of activity image and attenuation sinogram using time-of-flight positron emission tomography data consistency condition filtering. Journal Of Medical Imaging 2017, 4: 023502-023502. PMID: 28466027, PMCID: PMC5405780, DOI: 10.1117/1.jmi.4.2.023502.Peer-Reviewed Original ResearchData consistency conditionsMaximum likelihood attenuation correction factorsAttenuation sinogramConsistency conditionsJoint estimationJoint log-likelihood functionPET emission dataAttenuation correction factorsTime-of-flight (TOFActive imagingJoint estimation methodLog-likelihood functionPoisson noiseReconstruction resultsAttenuation correctionSinogram filteringPrevent convergenceEmission dataSinogramPositron emission tomography dataEstimation methodComputer simulationsPositron emission tomographyIterative methodCorrection factor
2014
Effect of time‐of‐flight and point spread function modeling on detectability of myocardial defects in PET
Schaefferkoetter J, Ouyang J, Rakvongthai Y, Nappi C, El Fakhri G. Effect of time‐of‐flight and point spread function modeling on detectability of myocardial defects in PET. Medical Physics 2014, 41: 062502. PMID: 24877836, PMCID: PMC4032408, DOI: 10.1118/1.4875725.Peer-Reviewed Original ResearchConceptsSignal-to-noise ratioDetection signal-to-noise ratioPoint spread functionObserver signal-to-noise ratioEffects of time-of-flightMyocardial defectsHuman observer performanceDefect detectionSlow convergenceTime-of-flight (TOFNon-PSFPostreconstruction smoothingFDG-PET dataTime-of-flightPSF reconstructionCombination of TOFNon-TOFIterationObserver performanceClinical practiceSpread functionReconstruction parametersReconstruction protocolsIterative methodDetection