2019
Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Berg P, Voß S, Janiga G, Saalfeld S, Bergersen A, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A, Chiu T, Tsang A, Copelli G, Csippa B, Paál G, Závodszky G, Detmer F, Chung B, Cebral J, Fujimura S, Takao H, Karmonik C, Elias S, Cancelliere N, Najafi M, Steinman D, Pereira V, Piskin S, Finol E, Pravdivtseva M, Velvaluri P, Rajabzadeh-Oghaz H, Paliwal N, Meng H, Seshadhri S, Venguru S, Shojima M, Sindeev S, Frolov S, Qian Y, Wu Y, Carlson K, Kallmes D, Dragomir-Daescu D, Beuing O. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment. International Journal Of Computer Assisted Radiology And Surgery 2019, 14: 1795-1804. PMID: 31054128, DOI: 10.1007/s11548-019-01986-2.Peer-Reviewed Original ResearchConceptsHemodynamic simulationsWall shear stressFlow characteristicsShear stressAspect ratioMultiple vorticesFlow resultsRupture probabilitySimulation setupSimulation capabilitiesSimulation approachInflow jetSimulationRuptured aneurysmsState-of-the-artHemodynamic quantificationIntracranial aneurysmsLocal Hemodynamic Conditions Associated with Focal Changes in the Intracranial Aneurysm Wall.
Cebral J, Detmer F, Chung B, Choque-Velasquez J, Rezai B, Lehto H, Tulamo R, Hernesniemi J, Niemela M, Yu A, Williamson R, Aziz K, Shakur S, Amin-Hanjani S, Charbel F, Tobe Y, Robertson A, Frösen J. Local Hemodynamic Conditions Associated with Focal Changes in the Intracranial Aneurysm Wall. American Journal Of Neuroradiology 2019, 40: 510-516. PMID: 30733253, PMCID: PMC6420361, DOI: 10.3174/ajnr.a5970.Peer-Reviewed Original ResearchConceptsWall shear stressOscillatory shear indexGradient oscillatory numberOscillatory wall shear stressShear stressShear indexRelative residence timeWall shear stress gradientAverage wall shear stressFlow conditionsComputational fluid dynamics modelThin regionShear stress gradientLocal hemodynamicsFluid dynamics modelRecirculation zoneSwirling flowResidence timeStress gradientAneurysm hemodynamicsImpingement siteDynamic pressureAneurysm regionDynamic modelFlow stream
2018
Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location
Detmer F, Chung B, Jimenez C, Hamzei-Sichani F, Kallmes D, Putman C, Cebral J. Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location. Neuroradiology 2018, 61: 275-284. PMID: 30456458, PMCID: PMC6403015, DOI: 10.1007/s00234-018-2135-9.Peer-Reviewed Original ResearchConceptsHigh wall shear stressWall shear stressOscillatory shearAdverse hemodynamic environmentShear stressComplex flowHemodynamic environmentComplex shapesImage-based modelingIrregular shapeMorphologySidewall aneurysmsBifurcationFlowSidewallShearShapeAdverse hemodynamicsMiddle cerebral arteryInternal carotid arteryDevelopment of a statistical model for discrimination of rupture status in posterior communicating artery aneurysms
Detmer F, Chung B, Mut F, Pritz M, Slawski M, Hamzei-Sichani F, Kallmes D, Putman C, Jimenez C, Cebral J. Development of a statistical model for discrimination of rupture status in posterior communicating artery aneurysms. Acta Neurochirurgica 2018, 160: 1643-1652. PMID: 29922867, PMCID: PMC6309378, DOI: 10.1007/s00701-018-3595-8.Peer-Reviewed Original ResearchConceptsWall shear stressComputational fluid dynamicsMinimum wall shear stressArterial wall shear stressImage-based computational fluid dynamicsShear stressFluid dynamicsGeometric parametersGeometric characteristicsNon-sphericity indexFlow velocityUnruptured PCOM aneurysmsBulge locationStatistical modelShear
2017
Angioarchitectures and Hemodynamic Characteristics of Posterior Communicating Artery Aneurysms and Their Association with Rupture Status
Chung B, Doddasomayajula R, Mut F, Detmer F, Pritz M, Hamzei-Sichani F, Brinjikji W, Kallmes D, Jimenez C, Putman C, Cebral J. Angioarchitectures and Hemodynamic Characteristics of Posterior Communicating Artery Aneurysms and Their Association with Rupture Status. American Journal Of Neuroradiology 2017, 38: 2111-2118. PMID: 28860212, PMCID: PMC5690887, DOI: 10.3174/ajnr.a5358.Peer-Reviewed Original ResearchConceptsWall shear stressShear stressMinimum wall shear stressWall shear stress distributionOscillatory wall shear stressRegions of elevated wall shear stressImage-based computational fluid dynamicsElevated wall shear stressFlow patternsShear stress distributionComputational fluid dynamicsInflow jetStress distributionFluid dynamicsAneurysm hemodynamicsHemodynamic characteristicsJetArtery bifurcationFlowRupture riskSidewallStressCharacteristics