Development and internal validation of an aneurysm rupture probability model based on patient characteristics and aneurysm location, morphology, and hemodynamics
Detmer F, Chung B, Mut F, Slawski M, Hamzei-Sichani F, Putman C, Jiménez C, Cebral J. Development and internal validation of an aneurysm rupture probability model based on patient characteristics and aneurysm location, morphology, and hemodynamics. International Journal Of Computer Assisted Radiology And Surgery 2018, 13: 1767-1779. PMID: 30094777, PMCID: PMC6328054, DOI: 10.1007/s11548-018-1837-0.Peer-Reviewed Original ResearchConceptsArea under the curveAneurysm locationMaximum oscillatory shear indexImage-based computational fluid dynamicsOscillatory shear indexComputational fluid dynamicsLow shear areaRisk of surgeryShear areaAdverse hemodynamic environmentShear indexFluid dynamicsHemodynamic environmentGeometric parametersPatient ageEndovascular treatmentIncreased rupture riskSubarachnoid hemorrhageAneurysm ruptureUnruptured aneurysmsPatient characteristicsTreatment strategiesInternal validityMale genderPatient genderDevelopment of a statistical model for discrimination of rupture status in posterior communicating artery aneurysms
Detmer F, Chung B, Mut F, Pritz M, Slawski M, Hamzei-Sichani F, Kallmes D, Putman C, Jimenez C, Cebral J. Development of a statistical model for discrimination of rupture status in posterior communicating artery aneurysms. Acta Neurochirurgica 2018, 160: 1643-1652. PMID: 29922867, PMCID: PMC6309378, DOI: 10.1007/s00701-018-3595-8.Peer-Reviewed Original ResearchConceptsWall shear stressComputational fluid dynamicsMinimum wall shear stressArterial wall shear stressImage-based computational fluid dynamicsShear stressFluid dynamicsGeometric parametersGeometric characteristicsNon-sphericity indexFlow velocityUnruptured PCOM aneurysmsBulge locationStatistical modelShear