2024
Resting-state functional MRI of the nose as a novel investigational window into the nervous system
Ponticorvo S, Paasonen J, Stenroos P, Salo R, Tanila H, Filip P, Rothman D, Eberly L, Garwood M, Metzger G, Gröhn O, Michaeli S, Mangia S. Resting-state functional MRI of the nose as a novel investigational window into the nervous system. Scientific Reports 2024, 14: 26352. PMID: 39487180, PMCID: PMC11530622, DOI: 10.1038/s41598-024-77615-z.Peer-Reviewed Original ResearchConceptsFunctional MRICentral nervous system integrityAutonomic nervous system innervationNervous system innervationAir-tissue interfaceNervous system integrityNervous system activityAutonomic nervous system activityAwake miceResting-state functional MRIAir intakeAbundant vasculatureCSF spacesNervous systemHeart rateSystem activityMRIBrain vesselsClearance sitesResting-stateSystem integrationHealthy participantsNoseSignal lossBreathing rate
2022
A 3D atlas of functional human brain energetic connectome based on neuropil distribution
Yu Y, Akif A, Herman P, Cao M, Rothman D, Carson R, Agarwal D, Evans A, Hyder F. A 3D atlas of functional human brain energetic connectome based on neuropil distribution. Cerebral Cortex 2022, 33: 3996-4012. PMID: 36104858, PMCID: PMC10068297, DOI: 10.1093/cercor/bhac322.Peer-Reviewed Original ResearchConceptsSynaptic densityCortical regionsHigher synapse densityHuman cortical circuitsFunctional imaging studiesCortical activity mapsVivo PET imagingNeuropil distributionGlucose oxidationSynapse densityCortical circuitsMetabolic rateSynaptic connectionsCortical energeticsImaging studiesHuman cortexPET imagingHistological stainingRecent evidenceCortexHuman brainBrainVoxel levelActivity ratesAtlas