2022
A 3D atlas of functional human brain energetic connectome based on neuropil distribution
Yu Y, Akif A, Herman P, Cao M, Rothman D, Carson R, Agarwal D, Evans A, Hyder F. A 3D atlas of functional human brain energetic connectome based on neuropil distribution. Cerebral Cortex 2022, 33: 3996-4012. PMID: 36104858, PMCID: PMC10068297, DOI: 10.1093/cercor/bhac322.Peer-Reviewed Original ResearchConceptsSynaptic densityCortical regionsHigher synapse densityHuman cortical circuitsFunctional imaging studiesCortical activity mapsVivo PET imagingNeuropil distributionGlucose oxidationSynapse densityCortical circuitsMetabolic rateSynaptic connectionsCortical energeticsImaging studiesHuman cortexPET imagingHistological stainingRecent evidenceCortexHuman brainBrainVoxel levelActivity ratesAtlas
1993
Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo.
Rothman D, Petroff O, Behar K, Mattson R. Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 5662-5666. PMID: 8516315, PMCID: PMC46781, DOI: 10.1073/pnas.90.12.5662.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidGABA concentrationGABA-transaminase inhibitor vigabatrinBrain gamma-aminobutyric acidDose-dependent elevationSeizure suppressionOccipital lobeHigh doseNonepileptic subjectsHuman volunteersHuman cortexVigabatrinDrug vigabatrinBrainPatientsHuman brainVolunteersCortexDose