2015
Distribution of temperature changes and neurovascular coupling in rat brain following 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) exposure
Coman D, Sanganahalli BG, Jiang L, Hyder F, Behar KL. Distribution of temperature changes and neurovascular coupling in rat brain following 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) exposure. NMR In Biomedicine 2015, 28: 1257-1266. PMID: 26286889, PMCID: PMC4573923, DOI: 10.1002/nbm.3375.Peer-Reviewed Original ResearchConceptsNeurovascular couplingBlood flowNeuronal activityNeural activityWhole-body hyperthermiaAbused psychostimulantMethylenedioxymethamphetamine (MDMA) exposureNeurovascular responseCortex temperatureMDMA effectsRat cortexRat brainBrain temperatureSubcortical regionsBrain regionsCortexSubcortexMDMA actionSkeletal muscleMonoaminergic stimulationBrainMDMACBFBody temperatureThermogenesis
2013
In vivo three‐dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution
Coman D, de Graaf R, Rothman DL, Hyder F. In vivo three‐dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution. NMR In Biomedicine 2013, 26: 1589-1595. PMID: 23881869, PMCID: PMC3800475, DOI: 10.1002/nbm.2995.Peer-Reviewed Original ResearchConceptsK-spaceNonexchanging protonsThree-dimensional molecular imagingParamagnetic lanthanide ionsRedundant deviationChemical shift imagingField of viewMolecular imaging capabilitiesMolecular imagingRapid data acquisitionProton detectionLanthanide ionsTens of minutesImaging capabilitiesMacrocyclic chelatesSpectroscopic signalsMacrocyclicCSI experimentsRelaxation timeHigh spatiotemporal resolutionParamagnetic agents
2010
Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5−and TmDOTMA−
Coman D, Trubel HK, Hyder F. Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5−and TmDOTMA−. NMR In Biomedicine 2010, 23: 277-285. PMID: 19957287, PMCID: PMC2843767, DOI: 10.1002/nbm.1461.Peer-Reviewed Original Research