2024
Diastolic dysfunction evaluation by cardiovascular magnetic resonance derived E, a, e’: Comparison to echocardiography
Lamy J, Xiang J, Shah N, Kwan J, Kim Y, Upadhyaya K, Reinhardt S, Meadows J, McNamara R, Baldassarre L, Peters D. Diastolic dysfunction evaluation by cardiovascular magnetic resonance derived E, a, e’: Comparison to echocardiography. Physiological Reports 2024, 12: e70078. PMID: 39604208, PMCID: PMC11602526, DOI: 10.14814/phy2.70078.Peer-Reviewed Original ResearchConceptsCardiovascular magnetic resonanceTransthoracic echocardiographyDiastolic dysfunctionDiastolic functionDiagnostic accuracy of cardiovascular magnetic resonanceEvaluate diastolic dysfunctionCardiovascular magnetic resonance imagingLeft atrial volumeMitral annular velocityHealthy age-matched subjectsComparison to echocardiographyMitral inflow velocityEvaluate diastolic functionAge-matched subjectsPresence of DDAtrial volumeDD gradeFirst-lineAnnular velocityDiagnostic accuracyImaging modalitiesMagnetic resonanceEchocardiographyALLTransthoracicStiffening of the human proximal pulmonary artery with increasing age
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.Peer-Reviewed Original ResearchConceptsProximal pulmonary arteriesPulmonary arteryAge-related stiffeningRight ventricular ejection fractionVentricular ejection fractionMean wall thicknessEjection fractionNo significant differenceSystemic circulationLuminal caliberDiffusing capacityArterial stiffeningIncreasing ageSignificant differenceDistensionArteryWall thicknessAdverse effectsWall strainVessel diameterCyclic biaxial strainOrgan donorsAgeMicrostructural remodeling
2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2019
Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2018
REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia
Hu C, Huber S, Latif SR, Santacana‐Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia. Journal Of Magnetic Resonance Imaging 2018, 49: 688-699. PMID: 30252987, DOI: 10.1002/jmri.26284.Peer-Reviewed Original ResearchAssessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure
Seemann F, Baldassarre LA, Llanos‐Chea F, Gonzales RA, Grunseich K, Hu C, Sugeng L, Meadows J, Heiberg E, Peters DC. Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure. Physiological Reports 2018, 6: e13828. PMID: 30187654, PMCID: PMC6125607, DOI: 10.14814/phy2.13828.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementMagnetic resonance imagingPulmonary capillary wedge pressureLA late gadolinium enhancementCapillary wedge pressureTransthoracic echocardiographyDiastolic functionDiastolic parametersWedge pressureAtrial remodelingFilling pressureCardiovascular magnetic resonance imagingLeft atrial remodelingVentricular filling pressureAtrial late gadolinium enhancementLGE-magnetic resonance imagingDiastolic dysfunctionMedical chartsLA volumeAtrial fibrosisGadolinium enhancementResonance imagingPressure catheterizationLow interobserverEchocardiography
2017
Reverse double inversion‐recovery: Improving motion robustness of cardiac T2‐weighted dark‐blood turbo spin‐echo sequence
Hu C, Huber S, Latif SR, Santacana‐Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. Reverse double inversion‐recovery: Improving motion robustness of cardiac T2‐weighted dark‐blood turbo spin‐echo sequence. Journal Of Magnetic Resonance Imaging 2017, 47: 1498-1508. PMID: 29112315, PMCID: PMC6346424, DOI: 10.1002/jmri.25886.Peer-Reviewed Original ResearchAdultAgedAlgorithmsArtifactsComputer SimulationDiastoleFemaleHealthy VolunteersHeartHeart DiseasesHeart VentriclesHumansImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMotionMyocardiumProspective StudiesQuality ControlReproducibility of ResultsSignal-To-Noise Ratio
2016
T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1
Hu C, Sinusas AJ, Huber S, Thorn S, Stacy MR, Mojibian H, Peters DC. T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1. Journal Of Cardiovascular Magnetic Resonance 2016, 19: 63. PMID: 28821300, PMCID: PMC5563030, DOI: 10.1186/s12968-017-0375-1.Peer-Reviewed Original ResearchAlgorithmsAnimalsCardiomyopathiesComputer SimulationContrast MediaFeasibility StudiesFemaleFibrosisHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedModels, CardiovascularMonte Carlo MethodOrganometallic CompoundsPhantoms, ImagingPredictive Value of TestsReproducibility of ResultsSus scrofaCMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation
Peters DC, Duncan JS, Grunseich K, Marieb MA, Cornfeld D, Sinusas AJ, Chelikani S. CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation. JACC Cardiovascular Imaging 2016, 10: 207-208. PMID: 27085430, PMCID: PMC5600154, DOI: 10.1016/j.jcmg.2016.01.015.Peer-Reviewed Original Research
2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2013
Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order
Shaw JL, Knowles BR, Goldfarb JW, Manning WJ, Peters DC. Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order. Journal Of Magnetic Resonance Imaging 2013, 40: 119-125. PMID: 24105717, PMCID: PMC5036388, DOI: 10.1002/jmri.24340.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAlgorithmsAtrial FibrillationBody WaterContrast MediaFemaleGadoliniumHeart AtriaHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial StunningPreoperative CarePulmonary VeinsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSubtraction TechniqueConceptsWater-fat separationThree‐dimensional late gadolinium‐enhanced mr imaging of the left atrium: A comparison of spiral versus Cartesian k‐space trajectories
Knowles BR, Peters DC, Clough RE, Razavi R, Schaeffter T, Prieto C. Three‐dimensional late gadolinium‐enhanced mr imaging of the left atrium: A comparison of spiral versus Cartesian k‐space trajectories. Journal Of Magnetic Resonance Imaging 2013, 39: 211-216. PMID: 24006356, DOI: 10.1002/jmri.24146.Peer-Reviewed Original ResearchAortic injury is common following pulmonary vein isolation
Tung P, Hong SN, Chan RH, Peters DC, Hauser TH, Manning WJ, Josephson ME. Aortic injury is common following pulmonary vein isolation. Heart Rhythm 2013, 10: 653-658. PMID: 23318348, DOI: 10.1016/j.hrthm.2013.01.012.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationVein isolationAortic blood poolPercent of patientsNumber of patientsCardiac magnetic resonanceLate gadolinium enhancementSignificant increaseAortic injuryEsophageal injuryAortic enhancementMediastinal structuresGadolinium enhancementPatientsControl groupAortaClinical implicationsHyperenhancementMean signal intensityBlood poolLGELatter groupLA enhancementInjuryLarger LA
2012
Respiratory bellows‐gated late gadolinium enhancement of the left atrium
Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows‐gated late gadolinium enhancement of the left atrium. Journal Of Magnetic Resonance Imaging 2012, 38: 1210-1214. PMID: 23197465, PMCID: PMC3812253, DOI: 10.1002/jmri.23954.Peer-Reviewed Original ResearchConceptsRight inferior pulmonary veinLate gadolinium enhancementRight superior PVAtrial fibrillationGadolinium enhancementRespiratory compensationScar presenceInferior pulmonary veinNav gatingPresence of scarAtrial imagingSuperior PVBlinded gradingPulmonary veinsLeft atriumTrue scarsPatientsQuadrantScarImproved assessmentFibrillationAtrium
2011
Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement
Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement. Magnetic Resonance In Medicine 2011, 66: 180-186. PMID: 21360738, PMCID: PMC3120912, DOI: 10.1002/mrm.22769.Peer-Reviewed Original Research
2010
Evaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse
Han Y, Peters DC, Kissinger KV, Goddu B, Yeon SB, Manning WJ, Nezafat R. Evaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse. The American Journal Of Cardiology 2010, 106: 243-248. PMID: 20599010, PMCID: PMC2929955, DOI: 10.1016/j.amjcard.2010.02.035.Peer-Reviewed Original ResearchConceptsMitral valve prolapseValve prolapseSystolic velocityPapillary musclesCMR imagingCardiovascular magnetic resonance imagingPapillary muscle functionHealthy adult subjectsMagnetic resonance imagingCardiovascular magnetic resonance techniquesPhase-contrast CMRAbnormal tractionElectrophysiologic stabilityPM tipsVentricular systoleMuscle functionLGE-CMRPatientsUnderlying myocardiumResonance imagingAdult subjectsProlapseCMRImagingFibrosisCircumferential myocardial strain in cardiomyopathy with and without left bundle branch block
Han Y, Chan J, Haber I, Peters DC, Zimetbaum PJ, Manning WJ, Yeon SB. Circumferential myocardial strain in cardiomyopathy with and without left bundle branch block. Journal Of Cardiovascular Magnetic Resonance 2010, 12: 2. PMID: 20047696, PMCID: PMC2806866, DOI: 10.1186/1532-429x-12-2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBundle-Branch BlockCardiac Pacing, ArtificialCardiomyopathiesCase-Control StudiesFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionObserver VariationPatient SelectionPredictive Value of TestsReproducibility of ResultsStroke VolumeSystoleVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft bundle branch blockNon-LBBB groupBundle branch blockCardiovascular magnetic resonanceCircumferential strainLBBB patientsVentricular levelBranch blockCardiomyopathy patientsHealthy controlsVentricular slicesContraction patternLeft ventricular contraction patternAdvanced heart failure patientsBackgroundCardiac resynchronization therapyDepressed systolic functionHeart failure patientsNon-LBBB patientsVentricular contraction patternCircumferential myocardial strainMyocardial circumferential strainNon-invasive parametersSystolic circumferential strainMid-ventricular levelCircumferential strain analysisLate Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations
MENG J, PETERS DC, HSING JM, CHUANG ML, CHAN J, FISH A, JOSEPHSON ME, MANNING WJ. Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations. Pacing And Clinical Electrophysiology 2010, 33: 661-666. PMID: 20059713, DOI: 10.1111/j.1540-8159.2009.02671.x.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationCardiovascular magnetic resonance imagingAtrial fibrillationVein isolationLGE-CMRPost-pulmonary vein isolationLate gadolinium enhancement cardiovascular magnetic resonance imagingEnhancement cardiovascular magnetic resonance imagingFrequent imaging findingsLeft atrium cavityLate gadolinium enhancementMagnetic resonance imagingEsophageal positionImaging findingsEsophageal locationGadolinium enhancementHyperenhancementNoninvasive assessmentVertebral bodyResonance imagingClinical implicationsAblation siteLonger ablation timePatientsCardiac MR
2009
Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance
Taclas JE, Nezafat R, Wylie JV, Josephson ME, Hsing J, Manning WJ, Peters DC. Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance. Heart Rhythm 2009, 7: 489-496. PMID: 20122877, PMCID: PMC2843771, DOI: 10.1016/j.hrthm.2009.12.007.Peer-Reviewed Original Research