2024
Diastolic dysfunction evaluation by cardiovascular magnetic resonance derived E, a, e’: Comparison to echocardiography
Lamy J, Xiang J, Shah N, Kwan J, Kim Y, Upadhyaya K, Reinhardt S, Meadows J, McNamara R, Baldassarre L, Peters D. Diastolic dysfunction evaluation by cardiovascular magnetic resonance derived E, a, e’: Comparison to echocardiography. Physiological Reports 2024, 12: e70078. PMID: 39604208, PMCID: PMC11602526, DOI: 10.14814/phy2.70078.Peer-Reviewed Original ResearchConceptsCardiovascular magnetic resonanceTransthoracic echocardiographyDiastolic dysfunctionDiastolic functionDiagnostic accuracy of cardiovascular magnetic resonanceEvaluate diastolic dysfunctionCardiovascular magnetic resonance imagingLeft atrial volumeMitral annular velocityHealthy age-matched subjectsComparison to echocardiographyMitral inflow velocityEvaluate diastolic functionAge-matched subjectsPresence of DDAtrial volumeDD gradeFirst-lineAnnular velocityDiagnostic accuracyImaging modalitiesMagnetic resonanceEchocardiographyALLTransthoracicStiffening of the human proximal pulmonary artery with increasing age
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.Peer-Reviewed Original ResearchConceptsProximal pulmonary arteriesPulmonary arteryAge-related stiffeningRight ventricular ejection fractionVentricular ejection fractionMean wall thicknessEjection fractionNo significant differenceSystemic circulationLuminal caliberDiffusing capacityArterial stiffeningIncreasing ageSignificant differenceDistensionArteryWall thicknessAdverse effectsWall strainVessel diameterCyclic biaxial strainOrgan donorsAgeMicrostructural remodeling
2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2019
FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study
Toczek J, Hillmer AT, Han J, Liu C, Peters D, Emami H, Wu J, Esterlis I, Cosgrove KP, Sadeghi MM. FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study. Journal Of Nuclear Cardiology 2019, 28: 688-694. PMID: 31073848, PMCID: PMC6842076, DOI: 10.1007/s12350-019-01724-w.Peer-Reviewed Original ResearchConceptsFDG-PET imagingPost-traumatic stress disorderFDG signalSystemic inflammationVascular inflammationCardiovascular diseaseBone marrowPET imagingFDG PET/CT imagingPilot case-control studyStress disorderCardiovascular risk factorsInflammatory biomarker levelsHealthy control subjectsPET/CT imagingCase-control studyPositron emission tomography (PET) imagingEmission Tomography ImagingInflammatory biomarkersControl subjectsBlood glucoseRisk factorsBiomarker levelsHealthy controlsProspective groupDynamic‐flip‐angle ECG‐gating with nuisance signal regression improves resting‐state BOLD functional connectivity mapping by reducing cardiogenic noise
Hu C, Tokoglu F, Scheinost D, Qiu M, Shen X, Peters DC, Galiana G, Constable RT. Dynamic‐flip‐angle ECG‐gating with nuisance signal regression improves resting‐state BOLD functional connectivity mapping by reducing cardiogenic noise. Magnetic Resonance In Medicine 2019, 82: 911-923. PMID: 31016782, DOI: 10.1002/mrm.27775.Peer-Reviewed Original ResearchLeft atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumeSUPER: A blockwise curve‐fitting method for accelerating MR parametric mapping with fast reconstruction
Hu C, Peters DC. SUPER: A blockwise curve‐fitting method for accelerating MR parametric mapping with fast reconstruction. Magnetic Resonance In Medicine 2019, 81: 3515-3529. PMID: 30656730, PMCID: PMC6435434, DOI: 10.1002/mrm.27662.Peer-Reviewed Original Research
2018
REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia
Hu C, Huber S, Latif SR, Santacana‐Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia. Journal Of Magnetic Resonance Imaging 2018, 49: 688-699. PMID: 30252987, DOI: 10.1002/jmri.26284.Peer-Reviewed Original ResearchAssessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure
Seemann F, Baldassarre LA, Llanos‐Chea F, Gonzales RA, Grunseich K, Hu C, Sugeng L, Meadows J, Heiberg E, Peters DC. Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure. Physiological Reports 2018, 6: e13828. PMID: 30187654, PMCID: PMC6125607, DOI: 10.14814/phy2.13828.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementMagnetic resonance imagingPulmonary capillary wedge pressureLA late gadolinium enhancementCapillary wedge pressureTransthoracic echocardiographyDiastolic functionDiastolic parametersWedge pressureAtrial remodelingFilling pressureCardiovascular magnetic resonance imagingLeft atrial remodelingVentricular filling pressureAtrial late gadolinium enhancementLGE-magnetic resonance imagingDiastolic dysfunctionMedical chartsLA volumeAtrial fibrosisGadolinium enhancementResonance imagingPressure catheterizationLow interobserverEchocardiography
2017
Reverse double inversion‐recovery: Improving motion robustness of cardiac T2‐weighted dark‐blood turbo spin‐echo sequence
Hu C, Huber S, Latif SR, Santacana‐Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. Reverse double inversion‐recovery: Improving motion robustness of cardiac T2‐weighted dark‐blood turbo spin‐echo sequence. Journal Of Magnetic Resonance Imaging 2017, 47: 1498-1508. PMID: 29112315, PMCID: PMC6346424, DOI: 10.1002/jmri.25886.Peer-Reviewed Original ResearchAdultAgedAlgorithmsArtifactsComputer SimulationDiastoleFemaleHealthy VolunteersHeartHeart DiseasesHeart VentriclesHumansImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMotionMyocardiumProspective StudiesQuality ControlReproducibility of ResultsSignal-To-Noise Ratio
2016
CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation
Peters DC, Duncan JS, Grunseich K, Marieb MA, Cornfeld D, Sinusas AJ, Chelikani S. CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation. JACC Cardiovascular Imaging 2016, 10: 207-208. PMID: 27085430, PMCID: PMC5600154, DOI: 10.1016/j.jcmg.2016.01.015.Peer-Reviewed Original Research
2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imagingAlgebraic reconstruction technique for parallel imaging reconstruction of undersampled radial data: Application to cardiac cine
Li S, Chan C, Stockmann JP, Tagare H, Adluru G, Tam LK, Galiana G, Constable RT, Kozerke S, Peters DC. Algebraic reconstruction technique for parallel imaging reconstruction of undersampled radial data: Application to cardiac cine. Magnetic Resonance In Medicine 2014, 73: 1643-1653. PMID: 24753213, PMCID: PMC4504217, DOI: 10.1002/mrm.25265.Peer-Reviewed Original Research
2013
Aortic injury is common following pulmonary vein isolation
Tung P, Hong SN, Chan RH, Peters DC, Hauser TH, Manning WJ, Josephson ME. Aortic injury is common following pulmonary vein isolation. Heart Rhythm 2013, 10: 653-658. PMID: 23318348, DOI: 10.1016/j.hrthm.2013.01.012.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationVein isolationAortic blood poolPercent of patientsNumber of patientsCardiac magnetic resonanceLate gadolinium enhancementSignificant increaseAortic injuryEsophageal injuryAortic enhancementMediastinal structuresGadolinium enhancementPatientsControl groupAortaClinical implicationsHyperenhancementMean signal intensityBlood poolLGELatter groupLA enhancementInjuryLarger LA
2011
Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement
Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement. Magnetic Resonance In Medicine 2011, 66: 180-186. PMID: 21360738, PMCID: PMC3120912, DOI: 10.1002/mrm.22769.Peer-Reviewed Original Research
2010
Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging
Harrigan CJ, Peters DC, Gibson CM, Maron BJ, Manning WJ, Maron MS, Appelbaum E. Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging. Radiology 2010, 258: 128-33. PMID: 21045187, DOI: 10.1148/radiol.10090526.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementHypertrophic cardiomyopathyGadolinium enhancementExtent of LGEMean signal intensityCardiovascular magnetic resonance imagingLGE cardiovascular magnetic resonance imagingNormal remote myocardiumVisual assessmentMagnetic resonance imagingInternal Review BoardStudy patientsMean ageBland-Altman analysisLarge cohortRemote myocardiumBody weightMore weeksPatientsSignal intensityResonance imagingGadopentetate dimeglumineMore SDsMR imagingReview boardEvaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse
Han Y, Peters DC, Kissinger KV, Goddu B, Yeon SB, Manning WJ, Nezafat R. Evaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse. The American Journal Of Cardiology 2010, 106: 243-248. PMID: 20599010, PMCID: PMC2929955, DOI: 10.1016/j.amjcard.2010.02.035.Peer-Reviewed Original ResearchConceptsMitral valve prolapseValve prolapseSystolic velocityPapillary musclesCMR imagingCardiovascular magnetic resonance imagingPapillary muscle functionHealthy adult subjectsMagnetic resonance imagingCardiovascular magnetic resonance techniquesPhase-contrast CMRAbnormal tractionElectrophysiologic stabilityPM tipsVentricular systoleMuscle functionLGE-CMRPatientsUnderlying myocardiumResonance imagingAdult subjectsProlapseCMRImagingFibrosisCircumferential myocardial strain in cardiomyopathy with and without left bundle branch block
Han Y, Chan J, Haber I, Peters DC, Zimetbaum PJ, Manning WJ, Yeon SB. Circumferential myocardial strain in cardiomyopathy with and without left bundle branch block. Journal Of Cardiovascular Magnetic Resonance 2010, 12: 2. PMID: 20047696, PMCID: PMC2806866, DOI: 10.1186/1532-429x-12-2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBundle-Branch BlockCardiac Pacing, ArtificialCardiomyopathiesCase-Control StudiesFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionObserver VariationPatient SelectionPredictive Value of TestsReproducibility of ResultsStroke VolumeSystoleVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft bundle branch blockNon-LBBB groupBundle branch blockCardiovascular magnetic resonanceCircumferential strainLBBB patientsVentricular levelBranch blockCardiomyopathy patientsHealthy controlsVentricular slicesContraction patternLeft ventricular contraction patternAdvanced heart failure patientsBackgroundCardiac resynchronization therapyDepressed systolic functionHeart failure patientsNon-LBBB patientsVentricular contraction patternCircumferential myocardial strainMyocardial circumferential strainNon-invasive parametersSystolic circumferential strainMid-ventricular levelCircumferential strain analysis
2009
Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Appelbaum E, Abraham JM, Pride YB, Harrigan CJ, Peters DC, Biller LH, Manning WJ, Gibson CM. Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. American Heart Journal 2009, 158: 84-91. PMID: 19540396, DOI: 10.1016/j.ahj.2009.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngioplasty, Balloon, CoronaryCardiac VolumeContrast MediaCoronary AngiographyCoronary CirculationElectrocardiographyEndocardiumFemaleGadolinium DTPAHeart VentriclesHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionMyocardial Reperfusion InjuryMyocardiumPericardiumPrognosisSignal Processing, Computer-AssistedThrombolytic TherapyTreatment OutcomeConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionMyocardial perfusion gradeInfarct border zoneMyocardial Infarction (TIMI) myocardial perfusion gradeElevation myocardial infarctionPercutaneous coronary interventionInfarct sizePerfusion gradeMyocardial perfusionInfarct surface areaCoronary interventionMyocardial infarctionInfarct architectureCardiovascular magnetic resonance measuresNormal epicardial flowDays of presentationMagnetic resonance measuresCardiovascular magnetic resonanceImpaired thrombolysisEpicardial flowThrombolysisPatientsPerfusionTMPGRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring