PET Group Publications

Morris ED: An Appreciation of The Gene: An Intimate History by Siddhartha Mukherjee and a Call for Expanded Training in the Responsible Conduct of Research. Yale J Biol Med. 2017 Dec; 2017 Dec 19. PMID: 29259530

Naganawa M, Gallezot JD, Rossano S, Carson RE: Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy. Bull Math Biol. 2017 Dec 11; 2017 Dec 11. PMID: 29230702

Calakos KC, Bhatt S, Foster DW, Cosgrove KP: Mechanisms Underlying Sex Differences in Cannabis Use. Curr Addict Rep. 2017 Dec; 2017 Oct 19. PMID: 29503790

Hillmer AT, Holden D, Fowles K, Nabulsi N, West BL, Carson RE, Cosgrove KP: Microglial depletion and activation: A [¹¹C]PBR28 PET study in nonhuman primates. EJNMMI Res. 2017 Dec; 2017 Jul 24. PMID: 28741281

Wu J, Liu H, Hashemi Zonouz T, Sandoval VM, Mohy-Ud-Din H, Lampert RJ, Sinusas AJ, Liu C, Liu YH: A blind deconvolution method incorporated with anatomical-based filtering for partial volume correction: Validations with ¹²³ I-mIBG cardiac SPECT/CT. Med Phys. 2017 Dec; 2017 Nov 6. PMID: 28994458

Kelada OJ, Rockwell S, Zheng MQ, Huang Y, Liu Y, Booth CJ, Decker RH, Oelfke U, Carson RE, Carlson DJ: Quantification of Tumor Hypoxic Fractions Using Positron Emission Tomography with [¹⁸F]Fluoromisonidazole ([¹⁸F]FMISO) Kinetic Analysis and Invasive Oxygen Measurements. Mol Imaging Biol. 2017 Dec. PMID: 28409339

Liu H, Zakiniaeiz Y, Cosgrove KP, Morris ED: Toward whole-brain dopamine movies: a critical review of PET imaging of dopamine transmission in the striatum and cortex. Brain Imaging Behav. 2017 Oct 25; 2017 Oct 25. PMID: 29071465

Labaree DC, Ropchan JR, Nabulsi N, Huang Y: A modification to improve the reliability of [¹¹ C]CN^- production in the GE radiochemistry system. J Labelled Comp Radiopharm. 2017 Oct; 2017 Sep 21. PMID: 28833348

Esterlis I, Holmes SE, Sharma P, Krystal JH, DeLorenzo C: Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies. Biol Psychiatry. 2017 Sep 19; 2017 Sep 19. PMID: 29100629

Zakiniaeiz Y, Cosgrove KP, Mazure CM, Potenza MN: Does Telescoping Exist in Male and Female Gamblers? Does It Matter? Front Psychol. 2017; 2017 Sep 5. PMID: 28928697

Karrer TM, Josef AK, Mata R, Morris ED, Samanez-Larkin GR: Reduced dopamine receptors and transporters but not synthesis capacity in normal aging adults: a meta-analysis. Neurobiol Aging. 2017 Sep; 2017 May 12. PMID: 28599217

Lattin CR, Stabile FA, Carson RE: Estradiol modulates neural response to conspecific and heterospecific song in female house sparrows: An in vivo positron emission tomography study. PLoS One. 2017; 2017 Aug 23. PMID: 28832614

Davis MT, DellaGioia N, Matuskey D, Harel B, Maruff P, Pietrzak RH, Esterlis I: Preliminary evidence concerning the pattern and magnitude of cognitive dysfunction in major depressive disorder using cogstate measures. J Affect Disord. 2017 Aug 15; 2017 Apr 27. PMID: 28460315

DeLorenzo C, Gallezot JD, Gardus J, Yang J, Planeta B, Nabulsi N, Ogden RT, Labaree DC, Huang YH, Mann JJ, Gasparini F, Lin X, Javitch JA, Parsey RV, Carson RE, Esterlis I: In vivo variation in same-day estimates of metabotropic glutamate receptor subtype 5 binding using [¹¹C]ABP688 and [¹⁸F]FPEB. J Cereb Blood Flow Metab. 2017 Aug; 2016 Jan 1. PMID: 27742888

Holmes SE, Girgenti MJ, Davis MT, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Duman RS, Carson RE, Krystal JH, Esterlis I, Traumatic Stress Brain Study Group.: Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence. Proc Natl Acad Sci U S A. 2017 Aug 1; 2017 Jul 17. PMID: 28716937

Wang L, Ye J, He Y, Deuther-Conrad W, Zhang J, Zhang X, Cui M, Steinbach J, Huang Y, Brust P, Jia H: ¹⁸F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain. Bioorg Med Chem. 2017 Jul 15; 2017 May 10. PMID: 28549890

Mohy-Ud-Din H, Boutagy NE, Stendahl JC, Zhuang ZW, Sinusas AJ, Liu C: Quantification of intramyocardial blood volume with ^99mTc-RBC SPECT-CT imaging: A preclinical study. J Nucl Cardiol. 2017 Jul 10; 2017 Jul 10. PMID: 28695406

Germino M, Gallezot JD, Yan J, Carson RE: Direct reconstruction of parametric images for brain PET with event-by-event motion correction: evaluation in two tracers across count levels. Phys Med Biol. 2017 Jul 7; 2017 May 15. PMID: 28504644

Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, Esterlis I: Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jul; 2017 Apr 6. PMID: 28993818

Bao W, Jia H, Finnema S, Cai Z, Carson RE, Huang YH: PET Imaging for Early Detection of Alzheimer's Disease: From Pathologic to Physiologic Biomarkers. PET Clin. 2017 Jul; 2017 May 2. PMID: 28576171

Ren S, Jin X, Chan C, Jian Y, Mulnix T, Liu C, Carson RE: Data-driven event-by-event respiratory motion correction using TOF PET list-mode centroid of distribution. Phys Med Biol. 2017 Jun 21; 2017 May 18. PMID: 28520558

Hillmer AT, Li S, Zheng MQ, Scheunemann M, Lin SF, Nabulsi N, Holden D, Pracitto R, Labaree D, Ropchan J, Teodoro R, Deuther-Conrad W, Esterlis I, Cosgrove KP, Brust P, Carson RE, Huang Y: PET imaging of α₇ nicotinic acetylcholine receptors: a comparative study of [¹⁸F]ASEM and [¹⁸F]DBT-10 in nonhuman primates, and further evaluation of [¹⁸F]ASEM in humans. Eur J Nucl Med Mol Imaging. 2017 Jun; 2017 Jan 24. PMID: 28120003

Baum E, Cai Z, Bois F, Holden D, Lin SF, Lara-Jaime T, Kapinos M, Chen Y, Deuther-Conrad W, Fischer S, Dukic-Stefanovic S, Bunse P, Wünsch B, Brust P, Jia H, Huang Y: PET Imaging Evaluation of Four σ₁ Radiotracers in Nonhuman Primates. J Nucl Med. 2017 Jun; 2017 Feb 23. PMID: 28232607

He Y, Xie F, Ye J, Deuther-Conrad W, Cui B, Wang L, Lu J, Steinbach J, Brust P, Huang Y, Lu J, Jia H: 1-(4-[¹⁸F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ₁ Receptors in the Brain. J Med Chem. 2017 May 25; 2017 May 8. PMID: 28409931

Liu Q, Mohy-Ud-Din H, Boutagy NE, Jiang M, Ren S, Stendahl JC, Sinusas AJ, Liu C: Fully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT. Phys Med Biol. 2017 May 21; 2017 Mar 7. PMID: 28266929

Petrulli JR, Hansen SB, Abourbeh G, Yaqub M, Bahce I, Holden D, Huang Y, Nabulsi NB, Contessa JN, Mishani E, Lammertsma AA, Morris ED: A multi species evaluation of the radiation dosimetry of [¹¹C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor. Nucl Med Biol. 2017 Apr; 2017 Jan 2. PMID: 28126682

Lattin CR, Pechenenko AV, Carson RE: Experimentally reducing corticosterone mitigates rapid captivity effects on behavior, but not body composition, in a wild bird. Horm Behav. 2017 Mar; 2017 Jan 5. PMID: 28065712

Gallezot JD, Planeta B, Nabulsi N, Palumbo D, Li X, Liu J, Rowinski C, Chidsey K, Labaree D, Ropchan J, Lin SF, Sawant-Basak A, McCarthy TJ, Schmidt AW, Huang Y, Carson RE: Determination of receptor occupancy in the presence of mass dose: [¹¹C]GSK189254 PET imaging of histamine H₃ receptor occupancy by PF-03654746. J Cereb Blood Flow Metab. 2017 Mar; 2016 Jul 20. PMID: 27207170

Worhunsky PD, Matuskey D, Gallezot JD, Gaiser EC, Nabulsi N, Angarita GA, Calhoun VD, Malison RT, Potenza MN, Carson RE: Regional and source-based patterns of [¹¹C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D₂ and D₃ receptor availability in cocaine-use disorder. Neuroimage. 2017 Mar 1; 2017 Jan 19. PMID: 28110088

Wang S, Kim S, Cosgrove KP, Morris ED: A framework for designing dynamic lp-ntPET studies to maximize the sensitivity to transient neurotransmitter responses to drugs: Application to dopamine and smoking. Neuroimage. 2017 Feb 1; 2016 Oct 13. PMID: 27743899

Sawant-Basak A, Chen L, Shaffer CL, Palumbo D, Schmidt A, Tseng E, Spracklin DK, Gallezot JD, Labaree D, Nabulsi N, Huang Y, Carson RE, McCarthy T: Quantitative projection of human brain penetration of the H₃ antagonist PF-03654746 by integrating rat-derived brain partitioning and PET receptor occupancy. Xenobiotica. 2017 Feb; 2016 Jun 29. PMID: 27353353

Cai Z, Li S, Pracitto R, Navarro A, Shirali A, Ropchan J, Huang Y: Fluorine-18-Labeled Antagonist for PET Imaging of Kappa Opioid Receptors. ACS Chem Neurosci. 2017 Jan 18; 2016 Oct 20. PMID: 27741398

Davis MT, Holmes SE, Pietrzak RH, Esterlis I: Neurobiology of Chronic Stress-Related Psychiatric Disorders: Evidence from Molecular Imaging Studies. Chronic Stress (Thousand Oaks). 2017 Jan-Dec; 2017 Jun 22. PMID: 29862379

Smith CT, Crawford JL, Dang LC, Seaman KL, San Juan MD, Vijay A, Katz DT, Matuskey D, Cowan RL, Morris ED, Zald DH, Samanez-Larkin GR: Partial-volume correction increases estimated dopamine D2-like receptor binding potential and reduces adult age differences. J Cereb Blood Flow Metab. 2017 Jan 1; 2017 Jan 1. PMID: 29090626

Finnema SJ, Nabulsi NB, Mercier J, Lin SF, Chen MK, Matuskey D, Gallezot JD, Henry S, Hannestad J, Huang Y, Carson RE: Kinetic evaluation and test-retest reproducibility of [¹¹C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans. J Cereb Blood Flow Metab. 2017 Jan 1; 2017 Jan 1. PMID: 28792356

Lin SF, Bois F, Holden D, Nabulsi N, Pracitto R, Gao H, Kapinos M, Teng JK, Shirali A, Ropchan J, Carson RE, Elmore CS, Vasdev N, Huang Y: The Search for a Subtype-Selective PET Imaging Agent for the GABA_A Receptor Complex: Evaluation of the Radiotracer [¹¹C]ADO in Nonhuman Primates. Mol Imaging. 2017 Jan-Dec. PMID: 28929924

England LJ, Aagaard K, Bloch M, Conway K, Cosgrove K, Grana R, Gould TJ, Hatsukami D, Jensen F, Kandel D, Lanphear B, Leslie F, Pauly JR, Neiderhiser J, Rubinstein M, Slotkin TA, Spindel E, Stroud L, Wakschlag L: Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products. Neurosci Biobehav Rev. 2017 Jan; 2016 Nov 24. PMID: 27890689

Zhang W, Cai Z, Li L, Ropchan J, Lim K, Boutagy NE, Wu J, Stendahl JC, Chu W, Gropler R, Sinusas AJ, Liu C, Huang Y: Optimized and Automated Radiosynthesis of [¹⁸F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography. Molecules. 2016 Dec 9; 2016 Dec 9. PMID: 27941676

Holmes SE, Esterlis I, Mazure CM, Lim YY, Ames D, Rainey-Smith S, Martins RN, Salvado O, Dore V, Villemagne VL, Rowe CC, Laws SM, Masters CL, Maruff P, Pietrzak RH, Australian Imaging, Biomarkers, Lifestyle Research Group.: β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men. Am J Geriatr Psychiatry. 2016 Dec; 2016 Aug 17. PMID: 27742526

Germino M, Ropchan J, Mulnix T, Fontaine K, Nabulsi N, Ackah E, Feringa H, Sinusas AJ, Liu C, Carson RE: Quantification of myocardial blood flow with (82)Rb: Validation with (15)O-water using time-of-flight and point-spread-function modeling. EJNMMI Res. 2016 Dec; 2016 Aug 1. PMID: 27650280

Huang YY, Cheng CY, Huang WS, Ma KH, Tseng TW, Chou TK, Huang Y, Shiue CY: Erratum to: Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18)F]AFM in rats and monkeys. EJNMMI Res. 2016 Dec; 2016 Sep 6. PMID: 27600887

Gaiser EC, Gallezot JD, Worhunsky PD, Jastreboff AM, Pittman B, Kantrovitz L, Angarita GA, Cosgrove KP, Potenza MN, Malison RT, Carson RE, Matuskey D: Elevated Dopamine D_2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [¹¹C](+)PHNO. Neuropsychopharmacology. 2016 Dec; 2016 Jul 4. PMID: 27374277

Naganawa M, Lin SF, Lim K, Labaree D, Ropchan J, Harris P, Huang Y, Ichise M, Carson RE, Cline GW: Evaluation of pancreatic VMAT2 binding with active and inactive enantiomers of ¹⁸F-FP-DTBZ in baboons. Nucl Med Biol. 2016 Dec; 2016 Sep 2. PMID: 27673755

Hillmer AT, Esterlis I, Gallezot JD, Bois F, Zheng MQ, Nabulsi N, Lin SF, Papke RL, Huang Y, Sabri O, Carson RE, Cosgrove KP: Imaging of cerebral α4β2* nicotinic acetylcholine receptors with (-)-[(18)F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain. Neuroimage. 2016 Nov 1; 2016 Jul 15. PMID: 27426839

Girgis RR, Slifstein M, D'Souza D, Lee Y, Periclou A, Ghahramani P, Laszlovszky I, Durgam S, Adham N, Nabulsi N, Huang Y, Carson RE, Kiss B, Kapás M, Abi-Dargham A, Rakhit A: Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [(11)C]-(+)-PHNO. Psychopharmacology (Berl). 2016 Oct; 2016 Aug 15. PMID: 27525990

Wang A, Huen SC, Luan HH, Yu S, Zhang C, Gallezot JD, Booth CJ, Medzhitov R: Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation. Cell. 2016 Sep 8. PMID: 27610573

Chen L, Nabulsi N, Naganawa M, Zasadny K, Skaddan MB, Zhang L, Najafzadeh S, Lin SF, Helal CJ, Boyden TL, Chang C, Ropchan J, Carson RE, Villalobos A, Huang Y: Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme. J Nucl Med. 2016 Sep; 2016 May 19. PMID: 27199356

Naganawa M, Waterhouse RN, Nabulsi N, Lin SF, Labaree D, Ropchan J, Tarabar S, DeMartinis N, Ogden A, Banerjee A, Huang Y, Carson RE: First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430. J Nucl Med. 2016 Sep; 2016 Apr 21. PMID: 27103022

Chan C, Liu H, Grobshtein Y, Stacy MR, Sinusas AJ, Liu C: Noise suppressed partial volume correction for cardiac SPECT/CT. Med Phys. 2016 Sep. PMID: 27587054

Esterlis I, Hillmer AT, Bois F, Pittman B, McGovern E, O'Malley SS, Picciotto MR, Yang BZ, Gelernter J, Cosgrove KP: CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation. Nicotine Tob Res. 2016 Sep; 2016 Mar 31. PMID: 27611310

Vijay A, Wang S, Worhunsky P, Zheng MQ, Nabulsi N, Ropchan J, Krishnan-Sarin S, Huang Y, Morris ED: PET imaging reveals sex differences in kappa opioid receptor availability in humans, in vivo. Am J Nucl Med Mol Imaging. 2016; 2016 Aug 20. PMID: 27648372

McClure-Begley TD, Esterlis I, Stone KL, Lam TT, Grady SR, Colangelo CM, Lindstrom JM, Marks MJ, Picciotto MR: Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex. eNeuro. 2016 Jul-Aug; 2016 Aug 16. PMID: 27559543

Cosgrove KP: A Need for Longitudinal Studies in the Addiction Field. Biol Psychiatry. 2016 Aug 1. PMID: 27402471

Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH: KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS. Depress Anxiety. 2016 Aug; 2016 Apr 6. PMID: 27062302

Wu J, Lin SF, Gallezot JD, Chan C, Prasad R, Thorn SL, Stacy MR, Huang Y, Zonouz TH, Liu YH, Lampert RJ, Carson RE, Sinusas AJ, Liu C: Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method. J Nucl Med. 2016 Aug; 2016 Apr 14. PMID: 27081169

Finnema SJ, Nabulsi NB, Eid T, Detyniecki K, Lin SF, Chen MK, Dhaher R, Matuskey D, Baum E, Holden D, Spencer DD, Mercier J, Hannestad J, Huang Y, Carson RE: Imaging synaptic density in the living human brain. Sci Transl Med. 2016 Jul 20. PMID: 27440727

Yu Y, Chan C, Ma T, Liu Y, Gallezot JD, Naganawa M, Kelada OJ, Germino M, Sinusas AJ, Carson RE, Liu C: Event-by-Event Continuous Respiratory Motion Correction for Dynamic PET Imaging. J Nucl Med. 2016 Jul; 2016 Feb 23. PMID: 26912437

Zakiniaeiz Y, Cosgrove KP, Potenza MN, Mazure CM: Balance of the Sexes: Addressing Sex Differences in Preclinical Research. Yale J Biol Med. 2016 Jun; 2016 Jun 27. PMID: 27354851

Groman SM, Smith NJ, Petrullli JR, Massi B, Chen L, Ropchan J, Huang Y, Lee D, Morris ED, Taylor JR: Dopamine D3 Receptor Availability Is Associated with Inflexible Decision Making. J Neurosci. 2016 Jun 22. PMID: 27335404

Ranganathan M, Cortes-Briones J, Radhakrishnan R, Thurnauer H, Planeta B, Skosnik P, Gao H, Labaree D, Neumeister A, Pittman B, Surti T, Huang Y, Carson RE, D'Souza DC: Reduced Brain Cannabinoid Receptor Availability in Schizophrenia. Biol Psychiatry. 2016 Jun 15; 2015 Aug 29. PMID: 26432420

Pittenger C, Adams TG Jr, Gallezot JD, Crowley MJ, Nabulsi N, James Ropchan, Gao H, Kichuk SA, Simpson R, Billingslea E, Hannestad J, Bloch M, Mayes L, Bhagwagar Z, Carson RE: OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding. J Affect Disord. 2016 May 15; 2016 Feb 9. PMID: 26919057

Nabulsi NB, Mercier J, Holden D, Carré S, Najafzadeh S, Vandergeten MC, Lin SF, Deo A, Price N, Wood M, Lara-Jaime T, Montel F, Laruelle M, Carson RE, Hannestad J, Huang Y: Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J Nucl Med. 2016 May; 2016 Feb 4. PMID: 26848175

Han L, Kong DK, Zheng MQ, Murikinati S, Ma C, Yuan P, Li L, Tian D, Cai Q, Ye C, Holden D, Park JH, Gao X, Thomas JL, Grutzendler J, Carson RE, Huang Y, Piepmeier JM, Zhou J: Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging. ACS Nano. 2016 Apr 26; 2016 Mar 16. PMID: 26967254

Matuskey D, Worhunksy P, Correa E, Pittman B, Gallezot JD, Nabulsi N, Ropchan J, Sreeram V, Gudepu R, Gaiser E, Cosgrove K, Ding YS, Potenza MN, Huang Y, Malison RT, Carson RE: Age-related changes in binding of the D2/3 receptor radioligand [(11)C](+)PHNO in healthy volunteers. Neuroimage. 2016 Apr 15; 2016 Feb 11. PMID: 26876475

Hillmer AT, Kloczynski T, Sandiego CM, Pittman B, Anderson JM, Labaree D, Gao H, Huang Y, Deluliis G, O'Malley SS, Carson RE, Cosgrove KP: Nicotine and Nicotine Abstinence Do Not Interfere with GABAA Receptor Neuroadaptations During Alcohol Abstinence. Alcohol Clin Exp Res. 2016 Apr; 2016 Mar 12. PMID: 26971694

Guo Z, Xu S, Du N, Liu J, Huang Y, Han M: Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system. Neurosci Lett. 2016 Mar 11; 2016 Jan 28. PMID: 26827716

Hillmer AT, Zheng MQ, Li S, Scheunemann M, Lin SF, Holden D, Labaree D, Ropchan J, Teodoro R, Deuther-Conrad W, Carson RE, Brust P, Huang Y: PET imaging evaluation of [(18)F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates. Eur J Nucl Med Mol Imaging. 2016 Mar; 2015 Oct 12. PMID: 26455500

Chen MK, Menard DH 3rd, Cheng DW: Determining the Minimal Required Radioactivity of 18F-FDG for Reliable Semiquantification in PET/CT Imaging: A Phantom Study. J Nucl Med Technol. 2016 Mar; 2016 Jan 14. PMID: 26769598

Zheng MQ, Lin SF, Holden D, Naganawa M, Ropchan JR, Najafzaden S, Kapinos M, Tabriz M, Carson RE, Hamill TG, Huang Y: Comparative evaluation of two glycine transporter 1 radiotracers [11C]GSK931145 and [18F]MK-6577 in baboons. Synapse. 2016 Mar; 2016 Jan 6. PMID: 26671330

Nicolas JM, Hannestad J, Holden D, Kervyn S, Nabulsi N, Tytgat D, Huang Y, Chanteux H, Staelens L, Matagne A, Mathy FX, Mercier J, Stockis A, Carson RE, Klitgaard H: Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action. Epilepsia. 2016 Feb; 2015 Dec 10. PMID: 26663401

Naganawa M, Dickinson GL, Zheng MQ, Henry S, Vandenhende F, Witcher J, Bell R, Nabulsi N, Lin SF, Ropchan J, Neumeister A, Ranganathan M, Tauscher J, Huang Y, Carson RE: Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11C-LY2795050. J Pharmacol Exp Ther. 2016 Feb; 2015 Dec 1. PMID: 26628406

D'Souza DC, Cortes-Briones JA, Ranganathan M, Thurnauer H, Creatura G, Surti T, Planeta B, Neumeister A, Pittman B, Normandin M, Kapinos M, Ropchan J, Huang Y, Carson RE, Skosnik PD: Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jan 1. PMID: 26858993

D'Souza DC, Cortes-Briones JA, Ranganathan M, Thurnauer H, Creatura G, Surti T, Planeta B, Neumeister A, Pittman B, Normandin MD, Kapinos M, Ropchan J, Huang Y, Carson RE, Skosnik PD: Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jan; 2015 Oct 22. PMID: 29560896

Chan C, Dey J, Grobshtein Y, Wu J, Liu YH, Lampert R, Sinusas AJ, Liu C: The impact of system matrix dimension on small FOV SPECT reconstruction with truncated projections. Med Phys. 2016 Jan. PMID: 26745914

Hillmer AT, Mason GF, Fucito LM, O'Malley SS, Cosgrove KP: How Imaging Glutamate, γ-Aminobutyric Acid, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal. Alcohol Clin Exp Res. 2015 Dec; 2015 Oct 28. PMID: 26510169

Xia Y, Zheng MQ, Holden D, Lin SF, Kapinos M, Ropchan J, Gallezot JD, Huang Y, Carson RE: Measurement of Bmax and Kd with the glycine transporter 1 radiotracer ¹⁸F-MK6577 using a novel multi-infusion paradigm. J Cereb Blood Flow Metab. 2015 Dec; 2015 Jul 22. PMID: 26198176

Fan P, Hutton BF, Holstensson M, Ljungberg M, Pretorius PH, Prasad R, Ma T, Liu Y, Wang S, Thorn SL, Stacy MR, Sinusas AJ, Liu C: Scatter and crosstalk corrections for (99m)Tc/(123)I dual-radionuclide imaging using a CZT SPECT system with pinhole collimators. Med Phys. 2015 Dec. PMID: 26632046

Teodoro R, Scheunemann M, Deuther-Conrad W, Wenzel B, Fasoli FM, Gotti C, Kranz M, Donat CK, Patt M, Hillmer A, Zheng MQ, Peters D, Steinbach J, Sabri O, Huang Y, Brust P: A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand. Molecules. 2015 Oct 9; 2015 Oct 9. PMID: 26473809

Sandiego CM, Gallezot JD, Pittman B, Nabulsi N, Lim K, Lin SF, Matuskey D, Lee JY, O'Connor KC, Huang Y, Carson RE, Hannestad J, Cosgrove KP: Imaging robust microglial activation after lipopolysaccharide administration in humans with PET. Proc Natl Acad Sci U S A. 2015 Oct 6; 2015 Sep 18. PMID: 26385967

Liu H, Chan C, Grobshtein Y, Ma T, Liu Y, Wang S, Stacy MR, Sinusas AJ, Liu C: Anatomical-based partial volume correction for low-dose dedicated cardiac SPECT/CT. Phys Med Biol. 2015 Sep 7; 2015 Aug 21. PMID: 26296043

Matuskey D, Gaiser EC, Gallezot JD, Angarita GA, Pittman B, Nabulsi N, Ropchan J, MaCleod P, Cosgrove KP, Ding YS, Potenza MN, Carson RE, Malison RT: A preliminary study of dopamine D2/3 receptor availability and social status in healthy and cocaine dependent humans imaged with [(11)C](+)PHNO. Drug Alcohol Depend. 2015 Sep 1; 2015 Jun 30. PMID: 26164205

Park E, Sullivan JM, Planeta B, Gallezot JD, Lim K, Lin SF, Ropchan J, McCarthy TJ, Ding YS, Morris ED, Williams WA, Huang Y, Carson RE: Test-retest reproducibility of the metabotropic glutamate receptor 5 ligand [¹⁸F]FPEB with bolus plus constant infusion in humans. Eur J Nucl Med Mol Imaging. 2015 Sep; 2015 Jun 5. PMID: 26044120

Normandin MD, Zheng MQ, Lin KS, Mason NS, Lin SF, Ropchan J, Labaree D, Henry S, Williams WA, Carson RE, Neumeister A, Huang Y: Imaging the cannabinoid CB1 receptor in humans with [11C]OMAR: assessment of kinetic analysis methods, test-retest reproducibility, and gender differences. J Cereb Blood Flow Metab. 2015 Aug; 2015 Apr 1. PMID: 25833345

Park E, Gallezot JD, Delgadillo A, Liu S, Planeta B, Lin SF, O'Connor KC, Lim K, Lee JY, Chastre A, Chen MK, Seneca N, Leppert D, Huang Y, Carson RE, Pelletier D: (11)C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas. Eur J Nucl Med Mol Imaging. 2015 Jun; 2015 Apr 2. PMID: 25833352

Hwang JJ, Yeckel CW, Gallezot JD, Aguiar RB, Ersahin D, Gao H, Kapinos M, Nabulsi N, Huang Y, Cheng D, Carson RE, Sherwin R, Ding YS: Imaging human brown adipose tissue under room temperature conditions with (11)C-MRB, a selective norepinephrine transporter PET ligand. Metabolism. 2015 Jun; 2015 Mar 5. PMID: 25798999

Bois F, Gallezot JD, Zheng MQ, Lin SF, Esterlis I, Cosgrove KP, Carson RE, Huang Y: Evaluation of [(18)F]-(-)-norchlorofluorohomoepibatidine ([(18)F]-(-)-NCFHEB) as a PET radioligand to image the nicotinic acetylcholine receptors in non-human primates. Nucl Med Biol. 2015 Jun; 2014 Aug 8. PMID: 25858513

Zheng MQ, Collier L, Bois F, Kelada OJ, Hammond K, Ropchan J, Akula MR, Carlson DJ, Kabalka GW, Huang Y: Synthesis of [(18)F]FMISO in a flow-through microfluidic reactor: Development and clinical application. Nucl Med Biol. 2015 Jun; 2015 Feb 7. PMID: 25779036

Gaiser EC, Matuskey D, Perkins E, D'Amico C, Abdelghany O, McKee SA, Cosgrove KP: A case series on the heightened autonomic response due to guanfacine and amphetamine interaction. J Clin Psychopharmacol. 2015 Apr. PMID: 25634160

Slifstein M, van de Giessen E, Van Snellenberg J, Thompson JL, Narendran R, Gil R, Hackett E, Girgis R, Ojeil N, Moore H, D'Souza D, Malison RT, Huang Y, Lim K, Nabulsi N, Carson RE, Lieberman JA, Abi-Dargham A: Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: a positron emission tomographic functional magnetic resonance imaging study. JAMA Psychiatry. 2015 Apr. PMID: 25651194

Verplaetse TL, Weinberger AH, Smith PH, Cosgrove KP, Mineur YS, Picciotto MR, Mazure CM, McKee SA: Targeting the noradrenergic system for gender-sensitive medication development for tobacco dependence. Nicotine Tob Res. 2015 Apr; 2015 Mar 11. PMID: 25762760

Weinberger AH, Smith PH, Allen SS, Cosgrove KP, Saladin ME, Gray KM, Mazure CM, Wetherington CL, McKee SA: Systematic and meta-analytic review of research examining the impact of menstrual cycle phase and ovarian hormones on smoking and cessation. Nicotine Tob Res. 2015 Apr. PMID: 25762750

Cosgrove KP, Veldhuizen MG, Sandiego CM, Morris ED, Small DM: Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum. Synapse. 2015 Apr; 2015 Mar 11. PMID: 25664726

Sandiego CM, Gallezot JD, Lim K, Ropchan J, Lin SF, Gao H, Morris ED, Cosgrove KP: Reference region modeling approaches for amphetamine challenge studies with [11C]FLB 457 and PET. J Cereb Blood Flow Metab. 2015 Mar 31; 2015 Mar 31. PMID: 25564239

Saricicek A, Chen J, Planeta B, Ruf B, Subramanyam K, Maloney K, Matuskey D, Labaree D, Deserno L, Neumeister A, Krystal JH, Gallezot JD, Huang Y, Carson RE, Bhagwagar Z: Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943. Eur J Nucl Med Mol Imaging. 2015 Mar; 2014 Nov 27. PMID: 25427881

Yoder KK, Territo PR, Hutchins GD, Hannestad J, Morris ED, Gallezot JD, Normandin MD, Cosgrove KP: Comparison of standardized uptake values with volume of distribution for quantitation of [(11)C]PBR28 brain uptake. Nucl Med Biol. 2015 Mar; 2014 Nov 15. PMID: 25487553

DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I: In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5. Biol Psychiatry. 2015 Feb 1; 2014 Jul 10. PMID: 25156701

Naganawa M, Zheng MQ, Henry S, Nabulsi N, Lin SF, Ropchan J, Labaree D, Najafzadeh S, Kapinos M, Tauscher J, Neumeister A, Carson RE, Huang Y: Test-retest reproducibility of binding parameters in humans with 11C-LY2795050, an antagonist PET radiotracer for the κ opioid receptor. J Nucl Med. 2015 Feb; 2015 Jan 15. PMID: 25593119

Lin SF, Labaree D, Chen MK, Holden D, Gallezot JD, Kapinos M, Teng JK, Najafzadeh S, Plisson C, Rabiner EA, Gunn RN, Carson RE, Huang Y: Further evaluation of [11C]MP-10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis. Synapse. 2015 Feb; 2014 Dec 11. PMID: 25450608

Chen MK, Cheng DW: What is the role of dosimetry in patients with advanced thyroid cancer? Curr Opin Oncol. 2015 Jan. PMID: 25319079

Cosgrove KP, Esterlis I, Sandiego C, Petrulli R, Morris ED: Imaging Tobacco Smoking with PET and SPECT. Curr Top Behav Neurosci. 2015. PMID: 25638332

Golestani R, Razavian M, Nie L, Zhang J, Jung JJ, Ye Y, de Roo M, Hilgerink K, Liu C, Robinson SP, Sadeghi MM: Imaging vessel wall biology to predict outcome in abdominal aortic aneurysm. Circ Cardiovasc Imaging. 2015 Jan; 2014 Dec 30. PMID: 25550400

Naganawa M, Mishina M, Sakata M, Oda K, Hiura M, Ishii K, Ishiwata K: Test-retest variability of adenosine A2A binding in the human brain with (11)C-TMSX and PET. EJNMMI Res. 2014 Dec; 2014 Dec 29. PMID: 25621197

Sirianni RW, Zheng MQ, Patel TR, Shafbauer T, Zhou J, Saltzman WM, Carson RE, Huang Y: Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography. Bioconjug Chem. 2014 Dec 17; 2014 Dec 1. PMID: 25322194

Cosgrove KP, McKay R, Esterlis I, Kloczynski T, Perkins E, Bois F, Pittman B, Lancaster J, Glahn DC, O'Malley S, Carson RE, Krystal JH: Tobacco smoking interferes with GABAA receptor neuroadaptations during prolonged alcohol withdrawal. Proc Natl Acad Sci U S A. 2014 Dec 16; 2014 Dec 1. PMID: 25453062

Cosgrove KP, Wang S, Kim SJ, McGovern E, Nabulsi N, Gao H, Labaree D, Tagare HD, Sullivan JM, Morris ED: Sex differences in the brain's dopamine signature of cigarette smoking. J Neurosci. 2014 Dec 10. PMID: 25505336

Lim K, Labaree D, Li S, Huang Y: Preparation of the metabotropic glutamate receptor 5 (mGluR5) PET tracer [(18)F]FPEB for human use: An automated radiosynthesis and a novel one-pot synthesis of its radiolabeling precursor. Appl Radiat Isot. 2014 Dec; 2014 Sep 18. PMID: 25305528

Cheng DW, Ersahin D, Staib LH, Della Latta D, Giorgetti A, d'Errico F: Using SUV as a guide to 18F-FDG dose reduction. J Nucl Med. 2014 Dec; 2014 Nov 13. PMID: 25453048

Matuskey D, Bhagwagar Z, Planeta B, Pittman B, Gallezot JD, Chen J, Wanyiri J, Najafzadeh S, Ropchan J, Geha P, Huang Y, Potenza MN, Neumeister A, Carson RE, Malison RT: Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans. Biol Psychiatry. 2014 Nov 15; 2013 Nov 28. PMID: 24433854

Naganawa M, Zheng MQ, Nabulsi N, Tomasi G, Henry S, Lin SF, Ropchan J, Labaree D, Tauscher J, Neumeister A, Carson RE, Huang Y: Kinetic modeling of (11)C-LY2795050, a novel antagonist radiotracer for PET imaging of the kappa opioid receptor in humans. J Cereb Blood Flow Metab. 2014 Nov; 2014 Sep 3. PMID: 25182664

Pietrzak RH, Naganawa M, Huang Y, Corsi-Travali S, Zheng MQ, Stein MB, Henry S, Lim K, Ropchan J, Lin SF, Carson RE, Neumeister A: Association of in vivo κ-opioid receptor availability and the transdiagnostic dimensional expression of trauma-related psychopathology. JAMA Psychiatry. 2014 Nov. PMID: 25229257

Castner SA, Murthy NV, Ridler K, Herdon H, Roberts BM, Weinzimmer DP, Huang Y, Zheng MQ, Rabiner EA, Gunn RN, Carson RE, Williams GV, Laruelle M: Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates. Neuropsychopharmacology. 2014 Nov; 2014 Feb 3. PMID: 24487737

Gallezot JD, Esterlis I, Bois F, Zheng MQ, Lin SF, Kloczynski T, Krystal JH, Huang Y, Sabri O, Carson RE, Cosgrove KP: Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys. Synapse. 2014 Nov; 2014 Jul 28. PMID: 25043426

Chan C, Harris M, Le M, Biondi J, Grobshtein Y, Liu YH, Sinusas AJ, Liu C: End-expiration respiratory gating for a high-resolution stationary cardiac SPECT system. Phys Med Biol. 2014 Oct 21; 2014 Sep 26. PMID: 25256033

Chen YY, Wang X, Zhang JM, Deuther-Conrad W, Zhang XJ, Huang Y, Li Y, Ye JJ, Cui MC, Steinbach J, Brust P, Liu BL, Jia HM: Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent. Bioorg Med Chem. 2014 Oct 1; 2014 Aug 12. PMID: 25189691

Liu C, Sinusas AJ: Is assessment of absolute myocardial perfusion with SPECT ready for prime time? J Nucl Med. 2014 Oct; 2014 Sep 18. PMID: 25236351

Naganawa M, Jacobsen LK, Zheng MQ, Lin SF, Banerjee A, Byon W, Weinzimmer D, Tomasi G, Nabulsi N, Grimwood S, Badura LL, Carson RE, McCarthy TJ, Huang Y: Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242. Neuroimage. 2014 Oct 1; 2014 May 17. PMID: 24844744

Pietrzak RH, Huang Y, Corsi-Travali S, Zheng MQ, Lin SF, Henry S, Potenza MN, Piomelli D, Carson RE, Neumeister A: Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. Neuropsychopharmacology. 2014 Oct; 2014 May 12. PMID: 24820537

Esterlis I, Ranganathan M, Bois F, Pittman B, Picciotto MR, Shearer L, Anticevic A, Carlson J, Niciu MJ, Cosgrove KP, D'Souza DC: In vivo evidence for β2 nicotinic acetylcholine receptor subunit upregulation in smokers as compared with nonsmokers with schizophrenia. Biol Psychiatry. 2014 Sep 15; 2013 Nov 13. PMID: 24360979

Kim SJ, Sullivan JM, Wang S, Cosgrove KP, Morris ED: Voxelwise lp-ntPET for detecting localized, transient dopamine release of unknown timing: sensitivity analysis and application to cigarette smoking in the PET scanner. Hum Brain Mapp. 2014 Sep; 2014 Apr 3. PMID: 24700424

Carpenter TO, Olear EA, Zhang JH, Ellis BK, Simpson CA, Cheng D, Gundberg CM, Insogna KL: Effect of paricalcitol on circulating parathyroid hormone in X-linked hypophosphatemia: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2014 Sep; 2014 Jul 16. PMID: 25029424

Sinusas AJ, Lazewatsky J, Brunetti J, Heller G, Srivastava A, Liu YH, Sparks R, Puretskiy A, Lin SF, Crane P, Carson RE, Lee LV: Biodistribution and radiation dosimetry of LMI1195: first-in-human study of a novel 18F-labeled tracer for imaging myocardial innervation. J Nucl Med. 2014 Sep; 2014 Jul 3. PMID: 24994931

Isaias IU, Spiegel J, Brumberg J, Cosgrove KP, Marotta G, Oishi N, Higuchi T, Küsters S, Schiller M, Dillmann U, van Dyck CH, Buck A, Herrmann K, Schloegl S, Volkmann J, Lassmann M, Fassbender K, Lorenz R, Samnick S: Nicotinic acetylcholine receptor density in cognitively intact subjects at an early stage of Parkinson's disease. Front Aging Neurosci. 2014; 2014 Aug 14. PMID: 25177294

Bowen SR, Pierce LA, Alessio AM, Liu C, Wollenweber SD, Stearns CW, Kinahan PE: Assessment of patient selection criteria for quantitative imaging with respiratory-gated positron emission tomography. J Med Imaging (Bellingham). 2014 Jul; 2014 Sep 24. PMID: 26158039

Zheng MQ, Kim SJ, Holden D, Lin SF, Need A, Rash K, Barth V, Mitch C, Navarro A, Kapinos M, Maloney K, Ropchan J, Carson RE, Huang Y: An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989. J Nucl Med. 2014 Jul; 2014 May 22. PMID: 24854795

Matuskey D, Gallezot JD, Pittman B, Williams W, Wanyiri J, Gaiser E, Lee DE, Hannestad J, Lim K, Zheng MQ, Lin SF, Labaree D, Potenza MN, Carson RE, Malison RT, Ding YS: Dopamine D₃ receptor alterations in cocaine-dependent humans imaged with [¹¹C](+)PHNO. Drug Alcohol Depend. 2014 Jun 1; 2014 Mar 20. PMID: 24717909

Gallezot JD, Zheng MQ, Lim K, Lin SF, Labaree D, Matuskey D, Huang Y, Ding YS, Carson RE, Malison RT: Parametric Imaging and Test-Retest Variability of ¹¹C-(+)-PHNO Binding to D₂/D₃ Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner. J Nucl Med. 2014 Jun; 2014 Apr 14. PMID: 24732151

Coman D, Sanganahalli BG, Cheng D, McCarthy T, Rothman DL, Hyder F: Mapping phosphorylation rate of fluoro-deoxy-glucose in rat brain by (19)F chemical shift imaging. Magn Reson Imaging. 2014 May; 2013 Dec 14. PMID: 24581725

Morris ED, Lucas MV, Petrulli JR, Cosgrove KP: How to design PET experiments to study neurochemistry: application to alcoholism. Yale J Biol Med. 2014 Mar; 2014 Mar 5. PMID: 24600335

Gallezot JD, Kloczynski T, Weinzimmer D, Labaree D, Zheng MQ, Lim K, Rabiner EA, Ridler K, Pittman B, Huang Y, Carson RE, Morris ED, Cosgrove KP: Imaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET. Neuropsychopharmacology. 2014 Mar; 2013 Oct 15. PMID: 24220025

Jin X, Mulnix T, Sandiego CM, Carson RE: Evaluation of frame-based and event-by-event motion-correction methods for awake monkey brain PET imaging. J Nucl Med. 2014 Feb; 2014 Jan 16. PMID: 24434295

Li CS, Potenza MN, Lee DE, Planeta B, Gallezot JD, Labaree D, Henry S, Nabulsi N, Sinha R, Ding YS, Carson RE, Neumeister A: Decreased norepinephrine transporter availability in obesity: Positron Emission Tomography imaging with (S,S)-[(11)C]O-methylreboxetine. Neuroimage. 2014 Feb 1; 2013 Oct 10. PMID: 24121204

Martinez D, Slifstein M, Nabulsi N, Grassetti A, Urban NB, Perez A, Liu F, Lin SF, Ropchan J, Mao X, Kegeles LS, Shungu DC, Carson RE, Huang Y: Imaging glutamate homeostasis in cocaine addiction with the metabotropic glutamate receptor 5 positron emission tomography radiotracer [(11)C]ABP688 and magnetic resonance spectroscopy. Biol Psychiatry. 2014 Jan 15; 2013 Sep 12. PMID: 24035345

Baldan LC, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, Ohtsu H, Bloch MH, Hughes ZA, Krystal JH, Mayes L, de Araujo I, Ding YS, State MW, Pittenger C: Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. Neuron. 2014 Jan 8. PMID: 24411733

Li S, Huang Y: In vivo imaging of the metabotropic glutamate receptor 1 (mGluR1) with positron emission tomography: recent advance and perspective. Curr Med Chem. 2014. PMID: 23992339

Liu J, Gao J, Tu S, Xu S, Liu Y, Shang W, Gu C, Huang Y, Han M: Neuroprotective Effects of Jitai Tablet, a Traditional Chinese Medicine, on the MPTP-Induced Acute Model of Parkinson's Disease: Involvement of the Dopamine System. Evid Based Complement Alternat Med. 2014; 2014 Apr 2. PMID: 24799940

Naganawa M, Nabulsi N, Planeta B, Gallezot JD, Lin SF, Najafzadeh S, Williams W, Ropchan J, Labaree D, Neumeister A, Huang Y, Carson RE: Tracer kinetic modeling of [(11)C]AFM, a new PET imaging agent for the serotonin transporter. J Cereb Blood Flow Metab. 2013 Dec; 2013 Aug 7. PMID: 23921898

Petrulli JR, Sullivan JM, Zheng MQ, Bennett DC, Charest J, Huang Y, Morris ED, Contessa JN: Quantitative analysis of [11C]-erlotinib PET demonstrates specific binding for activating mutations of the EGFR kinase domain. Neoplasia. 2013 Dec. PMID: 24403856

Hannestad JO, Cosgrove KP, DellaGioia NF, Perkins E, Bois F, Bhagwagar Z, Seibyl JP, McClure-Begley TD, Picciotto MR, Esterlis I: Changes in the cholinergic system between bipolar depression and euthymia as measured with [123I]5IA single photon emission computed tomography. Biol Psychiatry. 2013 Nov 15; 2013 Jun 14. PMID: 23773793

Sandiego CM, Jin X, Mulnix T, Fowles K, Labaree D, Ropchan J, Huang Y, Cosgrove K, Castner SA, Williams GV, Wells L, Rabiner EA, Carson RE: Awake nonhuman primate brain PET imaging with minimal head restraint: evaluation of GABAA-benzodiazepine binding with 11C-flumazenil in awake and anesthetized animals. J Nucl Med. 2013 Nov; 2013 Oct 10. PMID: 24115528

Pietrzak RH, Gallezot JD, Ding YS, Henry S, Potenza MN, Southwick SM, Krystal JH, Carson RE, Neumeister A: Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus. JAMA Psychiatry. 2013 Nov. PMID: 24048210

Chan C, Jin X, Fung EK, Naganawa M, Mulnix T, Carson RE, Liu C: Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. Med Phys. 2013 Nov. PMID: 24320466

Hannestad J, DellaGioia N, Gallezot JD, Lim K, Nabulsi N, Esterlis I, Pittman B, Lee JY, O'Connor KC, Pelletier D, Carson RE: The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: a [¹¹C]PBR28 PET study. Brain Behav Immun. 2013 Oct; 2013 Jul 9. PMID: 23850810

Jin X, Mulnix T, Gallezot JD, Carson RE: Evaluation of motion correction methods in human brain PET imaging--a simulation study based on human motion data. Med Phys. 2013 Oct. PMID: 24089924

Sirianni RW, Zheng MQ, Saltzman WM, Huang Y, Carson RE: Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography. Mol Imaging Biol. 2013 Oct. PMID: 23624949

Kim SJ, Zheng MQ, Nabulsi N, Labaree D, Ropchan J, Najafzadeh S, Carson RE, Huang Y, Morris ED: Determination of the in vivo selectivity of a new κ-opioid receptor antagonist PET tracer 11C-LY2795050 in the rhesus monkey. J Nucl Med. 2013 Sep; 2013 Aug 5. PMID: 23918735

Jin X, Chan C, Mulnix T, Panin V, Casey ME, Liu C, Carson RE: List-mode reconstruction for the Biograph mCT with physics modeling and event-by-event motion correction. Phys Med Biol. 2013 Aug 21; 2013 Jul 29. PMID: 23892635

Morris ED, Kim SJ, Sullivan JM, Wang S, Normandin MD, Constantinescu CC, Cosgrove KP: Creating dynamic images of short-lived dopamine fluctuations with lp-ntPET: dopamine movies of cigarette smoking. J Vis Exp. 2013 Aug 6; 2013 Aug 6. PMID: 23963311

Doddamane I, Butler R, Jhaveri A, Chung GG, Cheng D: Where does radioimmunotherapy fit in the management of breast cancer? Immunotherapy. 2013 Aug. PMID: 23902558

Sandiego CM, Nabulsi N, Lin SF, Labaree D, Najafzadeh S, Huang Y, Cosgrove K, Carson RE: Studies of the metabotropic glutamate receptor 5 radioligand [¹¹C]ABP688 with N-acetylcysteine challenge in rhesus monkeys. Synapse. 2013 Aug; 2013 Mar 27. PMID: 23424090

Zhou J, Patel TR, Sirianni RW, Strohbehn G, Zheng MQ, Duong N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ Jr, Piepmeier JM, Saltzman WM: Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proc Natl Acad Sci U S A. 2013 Jul 16; 2013 Jul 1. PMID: 23818631

Sullivan JM, Kim SJ, Cosgrove KP, Morris ED: Limitations of SRTM, Logan graphical method, and equilibrium analysis for measuring transient dopamine release with [(11)C]raclopride PET. Am J Nucl Med Mol Imaging. 2013; 2013 Apr 9. PMID: 23638336

Esterlis I, Hannestad JO, Perkins E, Bois F, D'Souza DC, Tyndale RF, Seibyl JP, Hatsukami DM, Cosgrove KP, O'Malley SS: Effect of a nicotine vaccine on nicotine binding to β2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers. Am J Psychiatry. 2013 Apr. PMID: 23429725

Sullivan JM, Lim K, Labaree D, Lin SF, McCarthy TJ, Seibyl JP, Tamagnan G, Huang Y, Carson RE, Ding YS, Morris ED: Kinetic analysis of the metabotropic glutamate subtype 5 tracer [(18)F]FPEB in bolus and bolus-plus-constant-infusion studies in humans. J Cereb Blood Flow Metab. 2013 Apr; 2012 Dec 19. PMID: 23250105

Tomasi G, Nabulsi N, Zheng MQ, Weinzimmer D, Ropchan J, Blumberg L, Brown-Proctor C, Ding YS, Carson RE, Huang Y: Determination of in vivo Bmax and Kd for 11C-GR103545, an agonist PET tracer for κ-opioid receptors: a study in nonhuman primates. J Nucl Med. 2013 Apr; 2013 Feb 19. PMID: 23424192

Fung EK, Carson RE: Cerebral blood flow with [15O]water PET studies using an image-derived input function and MR-defined carotid centerlines. Phys Med Biol. 2013 Mar 21; 2013 Feb 27. PMID: 23442733

Esterlis I, McKee SA, Kirk K, Lee D, Bois F, Stiklus SM, Seibyl JP, Krishnan-Sarin S, O'Malley SS, Staley JK, Cosgrove KP: Sex-specific differences in GABA(A) -benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving. Addict Biol. 2013 Mar; 2012 Feb 21. PMID: 22353491

Zheng MQ, Nabulsi N, Kim SJ, Tomasi G, Lin SF, Mitch C, Quimby S, Barth V, Rash K, Masters J, Navarro A, Seest E, Morris ED, Carson RE, Huang Y: Synthesis and evaluation of 11C-LY2795050 as a κ-opioid receptor antagonist radiotracer for PET imaging. J Nucl Med. 2013 Mar; 2013 Jan 25. PMID: 23353688

Lee DE, Gallezot JD, Zheng MQ, Lim K, Ding YS, Huang Y, Carson RE, Morris ED, Cosgrove KP: Test-retest reproducibility of [11C]-(+)-propyl-hexahydro-naphtho-oxazin positron emission tomography using the bolus plus constant infusion paradigm. Mol Imaging. 2013 Mar-Apr. PMID: 23415395

Potenza MN, Walderhaug E, Henry S, Gallezot JD, Planeta-Wilson B, Ropchan J, Neumeister A: Serotonin 1B receptor imaging in pathological gambling. World J Biol Psychiatry. 2013 Mar; 2011 Sep 22. PMID: 21936763

Esterlis I, Hannestad JO, Bois F, Sewell RA, Tyndale RF, Seibyl JP, Picciotto MR, Laruelle M, Carson RE, Cosgrove KP: Imaging changes in synaptic acetylcholine availability in living human subjects. J Nucl Med. 2013 Jan; 2012 Nov 15. PMID: 23160789

Sandiego CM, Weinzimmer D, Carson RE: Optimization of PET-MR registrations for nonhuman primates using mutual information measures: a Multi-Transform Method (MTM). Neuroimage. 2013 Jan 1; 2012 Aug 25. PMID: 22926293

Sherwin R, Slayman C, Rockwell S, Herold K, Williams K, Carson R, Mane S, Seow H, Max J, Johnson T: Yale Center for Clinical Investigation: leveraging industry partnerships and research cores. Clin Transl Sci. 2012 Dec. PMID: 23253663

Yan J, Planeta-Wilson B, Carson RE: Direct 4-D PET list mode parametric reconstruction with a novel EM algorithm. IEEE Trans Med Imaging. 2012 Dec; 2012 Aug 23. PMID: 22929383

Huang Y, Narendran R, Bischoff F, Guo N, Bae SA, Hwang DR, Lesage AS, Laruelle M: Synthesis and characterization of two PET radioligands for the metabotropic glutamate 1 (mGlu1) receptor. Synapse. 2012 Dec; 2012 Sep 29. PMID: 22927303

Hannestad J, Gallezot JD, Schafbauer T, Lim K, Kloczynski T, Morris ED, Carson RE, Ding YS, Cosgrove KP: Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primates. Neuroimage. 2012 Oct 15; 2012 Jul 6. PMID: 22776451

Lin SF, Fan X, Yeckel CW, Weinzimmer D, Mulnix T, Gallezot JD, Carson RE, Sherwin RS, Ding YS: Ex vivo and in vivo evaluation of the norepinephrine transporter ligand [11C]MRB for brown adipose tissue imaging. Nucl Med Biol. 2012 Oct; 2012 May 16. PMID: 22595487

Matuskey D, Pittman B, Planeta-Wilson B, Walderhaug E, Henry S, Gallezot JD, Nabulsi N, Ding YS, Bhagwagar Z, Malison R, Carson RE, Neumeister A: Age effects on serotonin receptor 1B as assessed by PET. J Nucl Med. 2012 Sep; 2012 Jul 31. PMID: 22851636

Saricicek A, Esterlis I, Maloney KH, Mineur YS, Ruf BM, Muralidharan A, Chen JI, Cosgrove KP, Kerestes R, Ghose S, Tamminga CA, Pittman B, Bois F, Tamagnan G, Seibyl J, Picciotto MR, Staley JK, Bhagwagar Z: Persistent β2*-nicotinic acetylcholinergic receptor dysfunction in major depressive disorder. Am J Psychiatry. 2012 Aug. PMID: 22772158

Normandin MD, Petersen KF, Ding YS, Lin SF, Naik S, Fowles K, Skovronsky DM, Herold KC, McCarthy TJ, Calle RA, Carson RE, Treadway JL, Cline GW: In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET. J Nucl Med. 2012 Jun; 2012 May 9. PMID: 22573821

Gallezot JD, Beaver JD, Gunn RN, Nabulsi N, Weinzimmer D, Singhal T, Slifstein M, Fowles K, Ding YS, Huang Y, Laruelle M, Carson RE, Rabiner EA: Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo. Synapse. 2012 Jun; 2012 Feb 24. PMID: 22213512

Cosgrove KP, Esterlis I, McKee SA, Bois F, Seibyl JP, Mazure CM, Krishnan-Sarin S, Staley JK, Picciotto MR, O'Malley SS: Sex differences in availability of β2*-nicotinic acetylcholine receptors in recently abstinent tobacco smokers. Arch Gen Psychiatry. 2012 Apr. PMID: 22474108

Hannestad J, Subramanyam K, Dellagioia N, Planeta-Wilson B, Weinzimmer D, Pittman B, Carson RE: Glucose metabolism in the insula and cingulate is affected by systemic inflammation in humans. J Nucl Med. 2012 Apr; 2012 Mar 13. PMID: 22414635

D'Souza DC, Esterlis I, Carbuto M, Krasenics M, Seibyl J, Bois F, Pittman B, Ranganathan M, Cosgrove K, Staley J: Lower ß2*-nicotinic acetylcholine receptor availability in smokers with schizophrenia. Am J Psychiatry. 2012 Mar. PMID: 22193533

Chen MK, Yasrebi M, Samii J, Staib LH, Doddamane I, Cheng DW: The utility of I-123 pretherapy scan in I-131 radioiodine therapy for thyroid cancer. Thyroid. 2012 Mar; 2012 Feb 2. PMID: 22300251

Wang Y, Lim K, Normandin M, Zhao X, Cline GW, Ding YS: Synthesis and evaluation of [18F]exendin (9-39) as a potential biomarker to measure pancreatic β-cell mass. Nucl Med Biol. 2012 Feb; 2011 Oct 26. PMID: 22033026

Wang X, Duffy P, McGee AW, Hasan O, Gould G, Tu N, Harel NY, Huang Y, Carson RE, Weinzimmer D, Ropchan J, Benowitz LI, Cafferty WB, Strittmatter SM: Recovery from chronic spinal cord contusion after Nogo receptor intervention. Ann Neurol. 2011 Nov. PMID: 22162062

Ersahin D, Doddamane I, Cheng D: Targeted radionuclide therapy. Cancers (Basel). 2011 Oct 11; 2011 Oct 11. PMID: 24213114

Singhal T, Ding YS, Weinzimmer D, Normandin MD, Labaree D, Ropchan J, Nabulsi N, Lin SF, Skaddan MB, Soeller WC, Huang Y, Carson RE, Treadway JL, Cline GW: Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes. Mol Imaging Biol. 2011 Oct; 2010 Sep 8. PMID: 20824509

Cosgrove KP, Kloczynski T, Nabulsi N, Weinzimmer D, Lin SF, Staley JK, Bhagwagar Z, Carson RE: Assessing the sensitivity of [¹¹C]p943, a novel 5-HT1B radioligand, to endogenous serotonin release. Synapse. 2011 Oct; 2011 May 3. PMID: 21484884

Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J: Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15; 2011 Jun 17. PMID: 21683344

Cosgrove KP, Esterlis I, Mason GF, Bois F, O'Malley SS, Krystal JH: Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence. Neuropharmacology. 2011 Jun; 2011 Jan 27. PMID: 21276806

Liu C, Alessio AM, Kinahan PE: Respiratory motion correction for quantitative PET/CT using all detected events with internal-external motion correlation. Med Phys. 2011 May. PMID: 21776808

Gallezot JD, Weinzimmer D, Nabulsi N, Lin SF, Fowles K, Sandiego C, McCarthy TJ, Maguire RP, Carson RE, Ding YS: Evaluation of [(11)C]MRB for assessment of occupancy of norepinephrine transporters: Studies with atomoxetine in non-human primates. Neuroimage. 2011 May 1; 2010 Sep 30. PMID: 20869448

Esterlis I, Mitsis EM, Batis JC, Bois F, Picciotto MR, Stiklus SM, Kloczynski T, Perry E, Seibyl JP, McKee S, Staley JK, Cosgrove KP: Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler. Int J Neuropsychopharmacol. 2011 Apr; 2010 Oct 29. PMID: 21029513

Vanstone MB, Udelsman RD, Cheng DW, Carpenter TO: Rapid correction of bone mass after parathyroidectomy in an adolescent with primary hyperparathyroidism. J Clin Endocrinol Metab. 2011 Feb; 2010 Nov 24. PMID: 21106715

Nabulsi NB, Zheng MQ, Ropchan J, Labaree D, Ding YS, Blumberg L, Huang Y: [11C]GR103545: novel one-pot radiosynthesis with high specific activity. Nucl Med Biol. 2011 Feb; 2010 Dec 3. PMID: 21315277

Cosgrove KP, Tellez-Jacques K, Pittman B, Petrakis I, Baldwin RM, Tamagnan G, Seibyl J, Kosten T, Staley JK: Dopamine and serotonin transporter availability in chronic heroin users: a [¹²³I]β-CIT SPECT imaging study. Psychiatry Res. 2010 Dec 30; 2010 Nov 3. PMID: 21050726

Hannestad J, Gallezot JD, Planeta-Wilson B, Lin SF, Williams WA, van Dyck CH, Malison RT, Carson RE, Ding YS: Clinically relevant doses of methylphenidate significantly occupy norepinephrine transporters in humans in vivo. Biol Psychiatry. 2010 Nov 1; 2010 Aug 5. PMID: 20691429

Liu C, Alessio A, Pierce L, Thielemans K, Wollenweber S, Ganin A, Kinahan P: Quiescent period respiratory gating for PET/CT. Med Phys. 2010 Sep. PMID: 20964223

Cosgrove KP, Kloczynski T, Bois F, Pittman B, Tamagnan G, Seibyl JP, Krystal JH, Staley JK: Decreased Beta(2)*-nicotinic acetylcholine receptor availability after chronic ethanol exposure in nonhuman primates. Synapse. 2010 Sep. PMID: 20340174

Esterlis I, Cosgrove KP, Batis JC, Bois F, Stiklus SM, Perkins E, Seibyl JP, Carson RE, Staley JK: Quantification of smoking-induced occupancy of beta2-nicotinic acetylcholine receptors: estimation of nondisplaceable binding. J Nucl Med. 2010 Aug; 2010 Jul 21. PMID: 20660383

Cosgrove KP, Staley JK, Baldwin RM, Bois F, Plisson C, Al-Tikriti MS, Seibyl JP, Goodman MM, Tamagnan GD: SPECT imaging with the serotonin transporter radiotracer [123I]p ZIENT in nonhuman primate brain. Nucl Med Biol. 2010 Jul; 2010 May 6. PMID: 20610163

Cosgrove KP, Esterlis I, McKee S, Bois F, Alagille D, Tamagnan GD, Seibyl JP, Krishnan-Sarin S, Staley JK: Beta2* nicotinic acetylcholine receptors modulate pain sensitivity in acutely abstinent tobacco smokers. Nicotine Tob Res. 2010 May; 2010 Apr 6. PMID: 20371741

Esterlis I, Cosgrove KP, Petrakis IL, McKee SA, Bois F, Krantzler E, Stiklus SM, Perry EB, Tamagnan GD, Seibyl JP, Krystal JH, Staley JK: SPECT imaging of nicotinic acetylcholine receptors in nonsmoking heavy alcohol drinking individuals. Drug Alcohol Depend. 2010 Apr 1; 2010 Jan 13. PMID: 20074869

Detterbeck F, Puchalski J, Rubinowitz A, Cheng D: Classification of the thoroughness of mediastinal staging of lung cancer. Chest. 2010 Feb. PMID: 20133290

Qiu M, Paul Maguire R, Arora J, Planeta-Wilson B, Weinzimmer D, Wang J, Wang Y, Kim H, Rajeevan N, Huang Y, Carson RE, Constable RT: Arterial transit time effects in pulsed arterial spin labeling CBF mapping: insight from a PET and MR study in normal human subjects. Magn Reson Med. 2010 Feb. PMID: 19953506

Nabulsi N, Huang Y, Weinzimmer D, Ropchan J, Frost JJ, McCarthy T, Carson RE, Ding YS: High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943. Nucl Med Biol. 2010 Feb; 2009 Dec 1. PMID: 20152720

Chen MK, Doddamane I, Cheng DW: Recombinant human thyroid-stimulating hormone as an alternative for thyroid hormone withdrawal in thyroid cancer management. Curr Opin Oncol. 2010 Jan. PMID: 19844179

Cosgrove KP: Imaging receptor changes in human drug abusers. Curr Top Behav Neurosci. 2010. PMID: 21161754

Huang Y, Zheng MQ, Gerdes JM: Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination? Curr Top Med Chem. 2010. PMID: 20583995

Gallezot JD, Nabulsi N, Neumeister A, Planeta-Wilson B, Williams WA, Singhal T, Kim S, Maguire RP, McCarthy T, Frost JJ, Huang Y, Ding YS, Carson RE: Kinetic modeling of the serotonin 5-HT(1B) receptor radioligand [(11)C]P943 in humans. J Cereb Blood Flow Metab. 2010 Jan; 2009 Sep 23. PMID: 19773803

Ding YS, Singhal T, Planeta-Wilson B, Gallezot JD, Nabulsi N, Labaree D, Ropchan J, Henry S, Williams W, Carson RE, Neumeister A, Malison RT: PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[(11)C]O-methylreboxetine and HRRT. Synapse. 2010 Jan. PMID: 19728366

Esterlis I, Cosgrove KP, Batis JC, Bois F, Kloczynski TA, Stiklus SM, Perry E, Tamagnan GD, Seibyl JP, Makuch R, Krishnan-Sarin S, O'Malley S, Staley JK: GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression. Synapse. 2009 Dec. PMID: 19642218

Yan J, Planeta-Wilson B, Gallezot JD, Carson RE: Initial Evaluation of Direct 4D Parametric Reconstruction with Human PET Data. IEEE Nucl Sci Symp Conf Rec (1997). 2009 Nov 1. PMID: 21278923

Jin X, Mulnix T, Planeta-Wilson B, Gallezot JD, Carson RE: Accuracy of Head Motion Compensation for the HRRT: Comparison of Methods. IEEE Nucl Sci Symp Conf Rec (1997). 2009 Oct 24. PMID: 20607125

Fung EK, Planeta-Wilson B, Mulnix T, Carson RE: A Multimodal Approach to Image-Derived Input Functions for Brain PET. IEEE Nucl Sci Symp Conf Rec (1997). 2009 Oct 24. PMID: 20607124

Mitsis EM, Reech KM, Bois F, Tamagnan GD, Macavoy MG, Seibyl JP, Staley JK, van Dyck CH: 123I-5-IA-85380 SPECT imaging of nicotinic receptors in Alzheimer disease and mild cognitive impairment. J Nucl Med. 2009 Sep; 2009 Aug 18. PMID: 19690024

Mitsis EM, Cosgrove KP, Staley JK, Bois F, Frohlich EB, Tamagnan GD, Estok KM, Seibyl JP, van Dyck CH: Age-related decline in nicotinic receptor availability with [(123)I]5-IA-85380 SPECT. Neurobiol Aging. 2009 Sep; 2008 Feb 1. PMID: 18242781

Cosgrove KP, Krantzler E, Frohlich EB, Stiklus S, Pittman B, Tamagnan GD, Baldwin RM, Bois F, Seibyl JP, Krystal JH, O'Malley SS, Staley JK: Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking. Neuropsychopharmacology. 2009 Sep; 2009 May 13. PMID: 19440191

Cosgrove KP, Batis J, Bois F, Maciejewski PK, Esterlis I, Kloczynski T, Stiklus S, Krishnan-Sarin S, O'Malley S, Perry E, Tamagnan G, Seibyl JP, Staley JK: beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking. Arch Gen Psychiatry. 2009 Jun. PMID: 19487632

Hausner SH, Alagille D, Koren AO, Amici L, Staley JK, Cosgrove KP, Baldwin RM, Tamagnan GD: Synthesis of 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles and their in vitro and in vivo evaluation as imaging agents for amyloid plaque. Bioorg Med Chem Lett. 2009 Jan 15; 2008 May 15. PMID: 19081717

Planeta-Wilson B, Yan J, Mulnix T, Carson RE: Quantitative Accuracy of HRRT List-mode Reconstructions: Effect of Low Statistics. IEEE Nucl Sci Symp Conf Rec (1997). 2008 Oct 1. PMID: 20617118

Czermak C, Staley JK, Kasserman S, Bois F, Young T, Henry S, Tamagnan GD, Seibyl JP, Krystal JH, Neumeister A: beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder. Int J Neuropsychopharmacol. 2008 May; 2008 Jan 11. PMID: 18190729

Yan J, Planeta-Wilson B, Carson RE: Direct 4D List Mode Parametric Reconstruction for PET with a Novel EM Algorithm. IEEE Nucl Sci Symp Conf Rec (1997). 2008. PMID: 20628540

Bois F, Baldwin RM, Amici L, Al-Tikriti MS, Kula N, Baldessarini R, Innis RB, Staley JK, Tamagnan GD: Synthesis, radiolabeling and baboon SPECT imaging of 2beta-carbomethoxy-3beta-(3'-[(123)I]iodophenyl)tropane ([(123)I]YP256) as a serotonin transporter radiotracer. Nucl Med Biol. 2008 Jan. PMID: 18158943

McCarthy TL, Hochberg RB, Labaree DC, Centrella M: 3-ketosteroid reductase activity and expression by fetal rat osteoblasts. J Biol Chem. 2007 Nov 23; 2007 Sep 28. PMID: 17905737

Cosgrove KP, Mazure CM, Staley JK: Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol Psychiatry. 2007 Oct 15; 2007 Jun 4. PMID: 17544382

Cosgrove KP, Mitsis EM, Bois F, Frohlich E, Tamagnan GD, Krantzler E, Perry E, Maciejewski PK, Epperson CN, Allen S, O'malley S, Mazure CM, Seibyl JP, van Dyck CH, Staley JK: 123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: effects of sex and menstrual phase. J Nucl Med. 2007 Oct; 2007 Sep 14. PMID: 17873128

Ariyan S, Ali-Salaam P, Cheng DW, Truini C: Reliability of lymphatic mapping after wide local excision of cutaneous melanoma. Ann Surg Oncol. 2007 Aug; 2007 Jun 1. PMID: 17541771

Huang Y, Williams WA: Enhanced selective serotonin re-uptake inhibitors as antidepressants: 2004 - 2006. Expert Opin Ther Pat. 2007 Aug. PMID: 20144065

Brian SR, Cheng DW, Goldberg PA: Unusual case of amiodarone-induced thyrotoxicosis: "illicit" use of a technetium scan to diagnose a transiently toxic thyroid nodule. Endocr Pract. 2007 Jul-Aug. PMID: 17669720

Wang TS, Cheng DW, Udelsman R: Contemporary imaging for thyroid cancer. Surg Oncol Clin N Am. 2007 Apr. PMID: 17560521

Mitsis EM, Cosgrove KP, Staley JK, Frohlich EB, Bois F, Tamagnan GD, Estok KM, Seibyl JP, Van Dyck CH: [123I]5-IA-85380 SPECT imaging of beta2-nicotinic acetylcholine receptor availability in the aging human brain. Ann N Y Acad Sci. 2007 Feb. PMID: 17413019

Shetty-Alva N, Cheng DW: Low-dose P32 therapy in essential thrombocythemia. Clin Nucl Med. 2006 Dec. PMID: 17117074

Neumeister A, Carson R, Henry S, Planeta-Wilson B, Binneman B, Maguire RP, Luckenbaugh DA, D'Souza C, Krystal JH, Frost JJ: Cerebral metabolic effects of intravenous glycine in healthy human subjects. J Clin Psychopharmacol. 2006 Dec. PMID: 17110816

Bennacef I, Haile CN, Schmidt A, Koren AO, Seibyl JP, Staley JK, Bois F, Baldwin RM, Tamagnan G: Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET. Bioorg Med Chem. 2006 Nov 15. PMID: 16908169

Bois F, Baldwin RM, Kula NS, Baldessarini RJ, Al Tikriti M, Innis RB, Tamagnan GD: Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine. Bioorg Med Chem Lett. 2006 Oct 1. PMID: 16908151

Lane M, Esterlis I, Tello A, Vesga-Lopez O, Zonana H, Jean-Baptiste M: Using the internet for clinical information gathering about unidentified psychiatric patients. J Psychiatr Pract. 2006 Sep. PMID: 16998422

Staley JK, Krishnan-Sarin S, Cosgrove KP, Krantzler E, Frohlich E, Perry E, Dubin JA, Estok K, Brenner E, Baldwin RM, Tamagnan GD, Seibyl JP, Jatlow P, Picciotto MR, London ED, O'Malley S, van Dyck CH: Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. J Neurosci. 2006 Aug 23. PMID: 16928859

Kuo PH, Cooper DL, Cheng DW: Recurrence of lymphoma presenting as asymmetrically increased testicular activity on FDG-PET/CT. Semin Nucl Med. 2006 Jan. PMID: 16356799

Kuo PH, Cheng DW, Sadar R: Diagnosis of septic joint in an immunosuppressed patient by twenty-four hour delayed imaging with Tc-99m HMPAO labeled white blood cell scan. Clin Nucl Med. 2005 Dec. PMID: 16319641

Kuo PH, Cheng DW: Artifactual spinal metastases imaged by PET/CT: a case report. J Nucl Med Technol. 2005 Dec. PMID: 16322123

Pappu S, Donovan P, Cheng D, Udelsman R: Sestamibi scans are not all created equally. Arch Surg. 2005 Apr. PMID: 15841562

Zhang JX, Labaree DC, Hochberg RB: Nonpolar and short side chain groups at C-11beta of estradiol result in antiestrogens. J Med Chem. 2005 Mar 10. PMID: 15743187

Zhang JX, Labaree DC, Mor G, Hochberg RB: Estrogen to antiestrogen with a single methylene group resulting in an unusual steroidal selective estrogen receptor modulator. J Clin Endocrinol Metab. 2004 Jul. PMID: 15240642

Bois F, Baldwin RM, Kula NS, Baldessarini RJ, Innis RB, Tamagnan G: Synthesis and monoamine transporter affinity of 3'-analogs of 2-beta-carbomethoxy-3-beta-(4'-iodophenyl)tropane (beta-CIT). Bioorg Med Chem Lett. 2004 May 3. PMID: 15080991

Centrella M, McCarthy TL, Chang WZ, Labaree DC, Hochberg RB: Estren (4-estren-3alpha,17beta-diol) is a prohormone that regulates both androgenic and estrogenic transcriptional effects through the androgen receptor. Mol Endocrinol. 2004 May; 2004 Feb 5. PMID: 14764654

Labaree DC, Zhang JX, Harris HA, O'Connor C, Reynolds TY, Hochberg RB: Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens. J Med Chem. 2003 May 8. PMID: 12723952