Raffaella Morotti, MD
Professor of Pathology and PediatricsCards
About
Research
Publications
2026
NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition
Kim A, Bhardwaj P, Rehman S, Zhao S, Lucas K, Noronha K, Bhatt D, Friedman S, Morotti R, Sundaram R, Dela Cruz F, Feinberg T, Ramakrishnan S, Xue W, Barkauskas D, Hall D, Shern J, Sun W, Barr F, Yi J, Spurrier J, Yu A, Brenner C, Heer C, Heske C, Vasquez J. NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition. Molecular Cancer Therapeutics 2026, 10.1158/1535-7163.mct-25-0619. PMID: 42017774, PMCID: PMC13184901, DOI: 10.1158/1535-7163.mct-25-0619.Peer-Reviewed Original Research5.23 Chronic Intestinal Pseudo-obstruction Versus Hirschsprung Disease
Morotti R, Jain D. 5.23 Chronic Intestinal Pseudo-obstruction Versus Hirschsprung Disease. 2026, 379-385. DOI: 10.1016/b978-0-323-82688-4.00110-2.Peer-Reviewed Original Research
2025
Pediatric Liver Tumors
Wu H, Patel K, Morotti R. Pediatric Liver Tumors. Practical Anatomic Pathology 2025, 423-438. DOI: 10.1007/978-3-031-97506-6_22.ChaptersHepatoblastoma: Comprehensive Review With Recent Updates
Jiao J, Saxena R, Morotti R. Hepatoblastoma: Comprehensive Review With Recent Updates. Advances In Anatomic Pathology 2025, 32: 309-316. PMID: 40178831, DOI: 10.1097/pap.0000000000000495.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Expanding the spectrum of progressive familial intrahepatic cholestasis: A report of 3 cases
Jiao J, Morotti R, Shafizadeh N, Jain D. Expanding the spectrum of progressive familial intrahepatic cholestasis: A report of 3 cases. American Journal Of Clinical Pathology 2024, 163: 332-339. PMID: 39333837, DOI: 10.1093/ajcp/aqae123.Peer-Reviewed Original ResearchPlacental Vascular Anastamoses and Associated Pathologies in Dichorionic Twin Gestations
Dave E, Bahtiyar M, Campbell W, Morotti R, Kohari K. Placental Vascular Anastamoses and Associated Pathologies in Dichorionic Twin Gestations. Twin Research And Human Genetics 2024, 27: 251-255. PMID: 39508257, DOI: 10.1017/thg.2024.35.Peer-Reviewed Original ResearchWhen lungs and weights tell different stories
Godse S, Brumer E, Kizilirmak T, Canapari C, Silva C, Morotti R, Jiang Y, Jeffries L, Chen L, Panacherry S. When lungs and weights tell different stories. Pediatric Pulmonology 2024, 59: 1047-1059. PMID: 38353400, DOI: 10.1002/ppul.26832.Peer-Reviewed Original ResearchMolecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules
Spaulding S, Maayah M, Dinauer C, Prasad M, Darbinyan A, Morotti R, Christison-Lagay E. Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules. Journal Of Pediatric Surgery 2024, 59: 975-980. PMID: 38246817, DOI: 10.1016/j.jpedsurg.2024.01.001.Peer-Reviewed Original Research
2022
Isolated Terminal Ileitis in Children
Alper A, Bennett A, Rottmann D, Morotti R, Escalera S, Phatak U, Pashankar D. Isolated Terminal Ileitis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2022, 76: 338-342. PMID: 36729703, DOI: 10.1097/mpg.0000000000003679.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Motility Disorders of the Gastrointestinal Tract
Morotti R, Jain D. Motility Disorders of the Gastrointestinal Tract. Practical Anatomic Pathology 2020, 313-337. DOI: 10.1007/978-3-030-51268-2_13.Chapters
Clinical Care
Overview
Raffaella Morotti, MD, is a specialist in pediatric pathology, a subspecialty dedicated to the diagnosis of diseases that affect children. She serves as director of pediatric pathology and associate director of the autopsy service for Yale Medicine.
Dr. Morotti’s work encompasses the diagnosis of malignant tumors in children, particularly blastomas and sarcomas, types of cancer that originate in the body in different ways. It also includes diagnosis of diseases of the gastrointestinal tract and liver. Dr. Morotti has a specific passion for and expertise in cholestatic diseases in infants and children—diseases that result when the flow of bile from the liver is reduced or blocked.
In addition, she is a perinatal pathologist with rare expertise in a unique field dealing with fetal malformations, placenta pathology, and perinatal autopsy.
Dr. Morotti says she is guided by the knowledge that children’s bodies are different than adult bodies. “The philosophy that guides pediatric pathology is the same one that guides the pediatric specialty in general and relies on the understanding that children are not little adults,” Dr. Morotti says. “They have specific diseases that call for dedicated physicians with specific training.”
Clinical Specialties
Fact Sheets
Pediatric Crohn's Disease
Learn More on Yale MedicinePediatric Ulcerative Colitis
Learn More on Yale MedicineDiagnosing Pediatric Sarcomas
Learn More on Yale Medicine
Board Certifications
Pediatric Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 1999
Anatomic Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 1997
News
News
- May 06, 2026
17 Pathology Faculty Members Listed Among Connecticut’s Top Doctors
- June 12, 2025
Pathology, Laboratory Medicine Residents, Fellows Feted at Graduation Ceremony
- May 01, 2024
Yale Pathology Faculty Members Recognized as Top Doctors
- May 29, 2020Source: Nature Medicine
Nature Medicine's COVID-19 Research in Brief: 9 May to 15 May, 2020
Get In Touch
Contacts
Locations
Yale Pathology
Academic Office
Lauder Hall
310 Cedar Street, Ste LH B13
New Haven, CT 06510
Appointments
203.737.6325Fax
203.785.3644