Christopher Pittenger MD, Ph.D.

Associate Professor of Psychiatry and in the Child Study Center and Assistant Professor of Psychology; Director, Yale OCD Research Clinic; Associate Director, Neuroscience Research Training Program

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience

Office of Student ResearchInterdepartmental Neuroscience ProgramChild Study Center: NIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders; Albert J. Solnit Integrated Training | Psychiatry: Connecticut Mental Health Center; Molecular Psychiatry, Division of; Clinical Neuroscience Research Unit; Obsessive Compulsive Disorder Research Clinic; PittLab

Research Interests

Learning and memory; Habit; CREB; Adeno-associated virus; Behavioral neurobiology; Magnetic resonance spectroscopy; Glutamate; Obsessive-compulsive disorder; Tourette syndrome more...


  • M.S., Yale University, 1994
  • B.S., Yale University, 1994
  • M.Phil., Columbia University, 1998
  • Ph.D., Columbia University, 2002
  • Ph.D., Columbia University Graduate School of Arts and Sciences, 2002
  • M.D., Columbia College of Physicians and Surgeons, 2003

Selected Publications

  • Xu, M., Kobets, A., Du, J.C., Lennington, J., Li, L., Banasr, M., Duman, R.S., Vaccarino, F.M., DiLeone, R.J., and Pittenger, C. (2015). Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proc. Natl. Acad. Sci. USA 112:893-8.
  • Calstellan Baldan, L., Williams, K.A., Gallezot, J.-D., Pogorelov, V., Rapanelli, M., Crowley, M., Anderson, G.M., Loring, E., Gorczyca, R., Billingslea, E., Wasylink, s., Panza, K.E., Ercan-Sencicek, A.G., Krusong, K., Leventhal, B.L., Ohtsu, H., Bloch, M.H., Hughes, Z.A., Krystal, J.H., Mayes, L., de Araujo, I., Ding, Y.-S., State, M.W., and Pittenger, C. (2014). Histidine decarboxylase deficiency causes Tourette syndrome: parallel findings in humans and mice. Neuron 81:77-90
  • Anticevic, A., Hu, S., Zhang, S., Savic, A., Billingslea, E., Wasylink, S., Repovs, G., Cole, M.W., Bednarski, S., Krystal, J.H., Bloch, M.H., Li, C.S., and Pittenger, C. (2014). Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder. Biological Psychiatry 75:595-605



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