Mark Anthony Perazella, MD

Professor of Medicine (Nephrology); Director, Acute Dialysis Unit

Research Interests

Research Organizations

Internal Medicine: Nephrology

Research Summary

  1. Diagnostic utility of urine microscopy in AKI:
    Urine sediment utility in distinguishing ATN from prerenal azotemia; Prognostic value of the urine sediment in predicting AKI severity;
  2. Adverse renal effects of therapeutic agents and other drugs;
  3. Hypotension in ESRD patients during Hemodialysis:
    Role of vasopressin deficiency in intradialytic hypotension (IDH); Utility of midodrine in treatment of IDH; Potential utility of vasopressin in the treatment of IDH
  4. HIV-related kidney disease:
    Diagnosis and management with HAART, Nephrotoxicity of therapeutic agents (HAART); Nephrogenic systemic fibrosis; Treatment with sodium thiosulfate.

Selected Publications

  • Perazella MA, Izzedine H. New drug toxicities in the onco-nephrology world. Kidney Int. 2015 Feb 11. doi: 10.1038/ki.2015.30.
  • Markowitz GS, Bomback AS, Perazella MA. Drug-Induced Glomerular Disease: Direct Cellular Injury. Clin J Am Soc Nephrol. 2015 Apr 10. pii: CJN.00860115. [Epub ahead of print]
  • Izzedine H, Perazella MA. Thrombotic Microangiopathy, Cancer, and Cancer Drugs. Am J Kidney Dis 2015 May 2. pii: S0272-6386(15)00543-0. doi: 10.1053/j.ajkd.2015.02.340. [Epub ahead of print]
  • Perazella MA. The Urine Sediment as a Biomarker of Kidney Disease. Am J Kidney Dis. 2015 May 2. pii: S0272-6386(15)00607-1. doi: 10.1053/j.ajkd.2015.02.342. [Epub ahead of print]
  • Luciano RL, Perazella MA. Crystalline-induced kidney disease: a case for urine microscopy. Clin Kidney J. 2015; 8(2):131-6.
  • Markowitz GS, Perazella MA: Acute phosphate nephropathy. Kidney Int 2009 Aug 12 [Epub ahead of print].
  • Perazella MA: Renal vulnerability to drug toxicity. Clin J Am Soc Nephrol 2009;4:1275-83.

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Contact Info

Mark Anthony Perazella, MD
Office Location
Yale NephrologyBoardman Building
330 Cedar Street, Ste Suite 122

New Haven, CT 06510
Mailing Address
Yale NephrologyPO Box 208029
New Haven, CT 06520–8029

Curriculum Vitae