Avlin Barlow Imaeda MD, PhD

Assistant Professor of Medicine (Digestive Diseases); Fellowship Program Director

Research Interests

Protective effects of low dose aspirin in liver disease; Patient preferences and barriers to patients seeking colonoscopic screening

Current Projects

I am beginning a project to evaluate patient preferences for different modes of colon cancer screening. I would like to compare colonoscopy, CT colonography and colon capsule endoscopy in hopes that we can better understand patient preferences and barriers to patients seeking colon cancer screening.

Research Summary

I have been involved in a project with Wajahat Mehal evaluating protective effects of aspirin in mouse models of liver disease and we have identified a previously unknown anti-inflammatory mechanism for aspirin. We are seeking support to initiate a small clinical trial to see whether low dose aspirin is protective in human liver disease.

Selected Publications

  • Imaeda, A., Sutterwala, F., Watanabe, A., Mahmood, S., Sohail, M., Flavell, R., Mehal, W. (2007, manuscript submitted) Acetaminophen induced hepatotoxicity is dependent on the NALP3 inflammasome and can be inhibited by aspirin.
  • Longacre, A., Imaeda, A., Garcia-Tsao, G., Fraenkel, L. (2007) A pilot project examining the predicted preferences of patients an dphysicians in the primary prophylaxis of variceal hemorrhage. Hepatology (published online Oct 12).
  • Rodes, J., Benhamou, J-P., Blei, A., Reichen, J., Rizzetto, M. ed Textbook of Hepatology. Blackwell Publishing (2007). “Chap 2.7.3 Antibody Production and Transport in the Liver.” Imaeda, A, Mehal, W. pp325-332.
  • Smith, D.S., Sullivan, L.E., Hay, S.F. ed. Field Guide to Internal Medicine. Lippincott, Williams & Wilkins 2005. “Chap 5 Infectious Diarrhea.” Imaeda, A.B.
  • Smith, D.S., Sullivan, L.E., Hay, S.F. ed. Field Guide to Internal Medicine. Lippincott Williams & Wilkins 2005. “Chap 69 Gastric Cancer.” Imaeda, A.B.

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