Jonathan B. Demb PhD

Associate Professor of Ophthalmology and Visual Science and of Cellular and Molecular Physiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): NeuroscienceInterdepartmental Neuroscience ProgramCellular & Molecular PhysiologyOphthalmology and Visual Science

Research Interests

Neuroscience; Functional circuitry of the retina; Cellular basis of visual adaptation; Neural plasticity; Mechanisms of retinal disease more...


  • BA, Boston University, 1993
  • Ph.D., Stanford University, 1997

Selected Publications

  • Park SJH, Kim IJ, Looger LL, Demb JB*, Borghuis BG* (2014). Excitatory synaptic inputs to mouse On-Off direction-selective retinal ganglion cells lack direction tuning. J. Neurosci., 34: 3976-3981. *co-corresponding authors.
  • Ke JB*, Wang YV*, Borghuis BG, Cembrowski MS, Riecke H, Kath WL, Demb JB+, Singer JH+ (2014). Adaptation to background light enables contrast coding at rod bipolar cell synapses. Neuron, 81: 388-401. *co-first authors, +co-corresponding authors.
  • Borghuis BG, Marvin JS, Looger LL, Demb JB (2013). Two-photon imaging of nonlinear glutamate release dynamics at bipolar cell synapses in the mouse retina. Journal of Neuroscience, 33: 10972-10985.



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