Eduardo Groisman PhD

Professor of Microbial Pathogenesis; HHMI Investigator

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Microbiology | Molecular Cell Biology, Genetics and Development

Microbial Sciences InstituteCenter for RNA Science and Medicine, YaleMicrobial Pathogenesis: Groisman Lab

Research Interests

Bacterial genetics; Signal transduction; Infectious diseases; Gene regulation; Bacteria-host interactions; Gut commensal bacteria more...


  • M.S., University of Buenos Aires, Argentina, 1980
  • Ph.D., University of Chicago, 1986

Selected Publications

  • A bacterial virulence protein promotes pathogenicity by inhibiting the bacterium's own F1Fo ATP synthase. Lee EJ, Pontes MH, Groisman EA. Cell. 2013 Jul 3;154(1):146-56. doi: 10.1016/j.cell.2013.06.004.
  • The lipopolysaccharide modification regulator PmrA limits Salmonella virulence by repressing the type three-secretion system Spi/Ssa. Choi J, Groisman EA. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9499-504. doi: 10.1073/pnas.1303420110. Epub 2013 May 20.
  • Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems. Townsend GE 2nd, Raghavan V, Zwir I, Groisman EA. Proc Natl Acad Sci U S A. 2013 Jan 8110(2):E161-9. doi: 10.1073/pnas.1212102110. Epub 2012 Dec 19.



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