2022
High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study
Mu Z, Palyo R, Goyal D, Sandoval V, Mu Z, Tao Z, Sinusas A, Miller E, Liu Y. High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study. 2022, 00: 1-4. DOI: 10.1109/nss/mic44845.2022.10399016.Peer-Reviewed Original ResearchTc-99m solutionHole imagesCardiac SPECTCardiac phantomMyocardial perfusion defectsField imagesParallel hole collimatorResolution of SPECTSub-endocardiumSubset expectation maximizationCZT detectorsSub-epicardiumHole collimatorPerfusion defectsHigh-resolutionOSEM algorithmCollimatorPhantom studyScanner configurationReconstruction technologyPhantomSPECT slicesTransmural perfusion gradientExpectation maximizationOSEM
2021
Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease
Feher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/circimaging.120.012208.Peer-Reviewed Original ResearchConceptsAutoimmune rheumatic diseasesMyocardial flow reserveLower myocardial flow reserveCox regression analysisAdverse eventsARDS diagnosisIndependent predictorsRheumatic diseasesPerfusion defectsFlow reserveNormal myocardial flow reserveLeft ventricular ejection fractionEnd pointGlobal myocardial flow reserveImpaired Myocardial Flow ReserveComorbidity-matched patientsSevere coronary calcificationCombined end pointCoronary microvascular dysfunctionHeart failure admissionsComposite end pointEvent-free survivalFramingham risk scoreLarge perfusion defectsRetrospective cohort analysis
2010
Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal Study
Mu Z, Dobrucki W, Hu X, Liu Y. Recent Progress on SPECT Imaging with Near-field Coded Aperture Collimation: A Small Animal Study. 2010, 3450-3453. DOI: 10.1109/nssmic.2010.5874447.Peer-Reviewed Original ResearchAnimal studiesOpen chest surgeryMyocardial perfusion defectsLeft ventricular myocardiumThree-dimensional single photon emissionSingle photon emissionVivo rat heartsPermanent myocardial infarctionCoronary arteryMyocardial infarctionSmall animal studiesPerfusion defectsJugular veinSurgical proceduresRadiotracer injectionVentricular myocardiumRat heartRatsLVAnimal imaging systemAnterior regionSmall animal imaging systemSPECTPhoton emissionSPECT technology