2023
CT attenuation correction improves quantitative risk prediction by cardiac SPECT in obese patients
Feher A, Pieszko K, Shanbhag A, Lemley M, Bednarski B, Miller R, Huang C, Miras L, Liu Y, Sinusas A, Slomka P, Miller E. CT attenuation correction improves quantitative risk prediction by cardiac SPECT in obese patients. European Journal Of Nuclear Medicine And Molecular Imaging 2023, 51: 695-706. PMID: 37924340, DOI: 10.1007/s00259-023-06484-x.Peer-Reviewed Original ResearchMajor adverse cardiac eventsMyocardial perfusion imagingSPECT myocardial perfusion imagingMACE-free survivalObese patientsPrognostic valueSignificant incremental prognostic valueYale-New Haven HospitalLate coronary revascularizationStress total perfusion deficitAdverse cardiac eventsIncremental prognostic valueNonfatal myocardial infarctionComposite end pointCT myocardial perfusion imagingSuperior prognostic valueSPECT/CT myocardial perfusion imagingTotal perfusion deficitNew Haven HospitalCT attenuation correctionHighest ROC areaStress TPDCoronary revascularizationCardiac eventsPatient populationComparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging
Feher A, Pieszko K, Shanbhag A, Lemley M, Miller R, Huang C, Miras L, Liu Y, Gerber J, Sinusas A, Miller E, Slomka P. Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging. The International Journal Of Cardiovascular Imaging 2023, 40: 185-193. PMID: 37845406, PMCID: PMC466934, DOI: 10.1007/s10554-023-02980-1.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsCoronary artery calcificationMyocardial perfusion imagingCT myocardial perfusion imagingSPECT/CT myocardial perfusion imagingArtery calcificationPrognostic valuePrior coronary stentingAdverse cardiovascular eventsSimilar prognostic valueSPECT myocardial perfusionREFINE SPECT registrySPECT/CTCardiovascular eventsCAC scoringCalcium scoreCoronary calcificationCoronary stentingPrognostic utilitySingle centerCoronary arteryLow doseMyocardial perfusionPerfusion imagingSurvival analysisIN PATIENTS UNDERGOING NUCLEAR MYOCARDIAL PERFUSION IMAGING, RHEUMATOID ARTHRITIS IS ASSOCIATED WITH INCREASED RISK OF ADVERSE CARDIOVASCULAR EVENTS INDEPENDENT OF MYOCARDIAL ISCHEMIA
Pires J, Oikonomou E, Agarwal R, Liu Y, miller E, Sinusas A, Feher A. IN PATIENTS UNDERGOING NUCLEAR MYOCARDIAL PERFUSION IMAGING, RHEUMATOID ARTHRITIS IS ASSOCIATED WITH INCREASED RISK OF ADVERSE CARDIOVASCULAR EVENTS INDEPENDENT OF MYOCARDIAL ISCHEMIA. Journal Of The American College Of Cardiology 2023, 81: 1467. DOI: 10.1016/s0735-1097(23)01911-3.Peer-Reviewed Original Research
2022
Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging
Feher A, Pieszko K, Miller R, Lemley M, Shanbhag A, Huang C, Miras L, Liu YH, Sinusas AJ, Miller EJ, Slomka PJ. Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology 2022, 30: 590-603. PMID: 36195826, DOI: 10.1007/s12350-022-03099-x.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsMyocardial perfusion imagingAdverse cardiovascular eventsSPECT myocardial perfusion imagingCAC scoringCardiovascular eventsPrediction of MACECoronary artery calcification (CAC) scoringMACE-free survivalClinical risk factorsCoronary artery calciumCT myocardial perfusion imagingReceiver operator characteristic curveSPECT/CT myocardial perfusion imagingSPECT/CTOperator characteristic curveCT myocardial perfusionArtery calciumCAC scoreAnalysis patientsMACE predictionSingle centerHigher event ratesRisk factorsRisk score
2021
Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning
Liu H, Wu J, Miller EJ, Liu C, Yaqiang, Liu, Liu YH. Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2793-2800. PMID: 33511425, DOI: 10.1007/s00259-021-05202-9.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingCoronary artery diseaseMyocardial perfusion abnormalitiesPerfusion abnormalitiesDiagnostic accuracyConvolutional neural networkTomography myocardial perfusion imagingYale-New Haven HospitalMyocardial perfusion defect sizeSPECT myocardial perfusion imagingAbnormal myocardial perfusionReceiver-operating characteristic curvePerfusion defect sizeNew Haven HospitalAUC valuesSingle photon emissionMyocardial perfusion SPECTDeep learningHigh diagnostic accuracyArtery diseaseDL methodsFinal diagnosisPatient genderMyocardial perfusionPerfusion SPECT