2016
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants
Zhou B, Lu Y, Hajifathalian K, Bentham J, Di Cesare M, Danaei G, Bixby H, Cowan M, Ali M, Taddei C, Lo W, Reis-Santos B, Stevens G, Riley L, Miranda J, Bjerregaard P, Rivera J, Fouad H, Ma G, Mbanya J, McGarvey S, Mohan V, Onat A, Pilav A, Ramachandran A, Romdhane H, Paciorek C, Bennett J, Ezzati M, Abdeen Z, Abdul Kadir K, Abu-Rmeileh N, Acosta-Cazares B, Adams R, Aekplakorn W, Aguilar-Salinas C, Agyemang C, Ahmadvand A, Al-Othman A, Alkerwi A, Amouyel P, Amuzu A, Andersen L, Anderssen S, Anjana R, Aounallah-Skhiri H, Aris T, Arlappa N, Arveiler D, Assah F, Avdicová M, Azizi F, Balakrishna N, Bandosz P, Barbagallo C, Barceló A, Batieha A, Baur L, Romdhane H, Benet M, Bernabe-Ortiz A, Bharadwaj S, Bhargava S, Bi Y, Bjerregaard P, Bjertness E, Bjertness M, Björkelund C, Blokstra A, Bo S, Boehm B, Boissonnet C, Bovet P, Brajkovich I, Breckenkamp J, Brenner H, Brewster L, Brian G, Bruno G, Bugge A, Cabrera de León A, Can G, Cândido A, Capuano V, Carlsson A, Carvalho M, Casanueva F, Casas J, Caserta C, Castetbon K, Chamukuttan S, Chaturvedi N, Chen C, Chen F, Chen S, Cheng C, Chetrit A, Chiou S, Cho Y, Chudek J, Cifkova R, Claessens F, Concin H, Cooper C, Cooper R, Costanzo S, Cottel D, Cowell C, Crujeiras A, D'Arrigo G, Dallongeville J, Dankner R, Dauchet L, de Gaetano G, De Henauw S, Deepa M, Dehghan A, Deschamps V, Dhana K, Di Castelnuovo A, Djalalinia S, Doua K, Drygas W, Du Y, Dzerve V, Egbagbe E, Eggertsen R, El Ati J, Elosua R, Erasmus R, Erem C, Ergor G, Eriksen L, Escobedo-de la Peña J, Fall C, Farzadfar F, Felix-Redondo F, Ferguson T, Fernández-Bergés D, Ferrari M, Ferreccio C, Feskens E, Finn J, Föger B, Foo L, Forslund A, Fouad H, Francis D, Franco Mdo C, Franco O, Frontera G, Furusawa T, Gaciong Z, Garnett S, Gaspoz J, Gasull M, Gates L, Geleijnse J, Ghasemian A, Ghimire A, Giampaoli S, Gianfagna F, Giovannelli J, Giwercman A, Gross M, González Rivas J, Gorbea M, Gottrand F, Grafnetter D, Grodzicki T, Grøntved A, Gruden G, Gu D, Guan O, Guerrero R, Guessous I, Guimaraes A, Gutierrez L, Hambleton I, Hardy R, Hari Kumar R, Hata J, He J, Heidemann C, Herrala S, Hihtaniemi I, Ho S, Ho S, Hofman A, Hormiga C, Horta B, Houti L, Howitt C, Htay T, Htet A, Htike M, Hu Y, Hussieni A, Huybrechts I, Hwalla N, Iacoviello L, Iannone A, Ibrahim M, Ikeda N, Ikram M, Irazola V, Islam M, Iwasaki M, Jacobs J, Jafar T, Jamil K, Jasienska G, Jiang C, Jonas J, Joshi P, Kafatos A, Kalter-Leibovici O, Kasaeian A, Katz J, Kaur P, Kavousi M, Keinänen-Kiukaanniemi S, Kelishadi R, Kengne A, Kersting M, Khader Y, Khalili D, Khang Y, Kiechl S, Kim J, Kolsteren P, Korrovits P, Kratzer W, Kromhout D, Kujala U, Kula K, Kyobutungi C, Laatikainen T, Lachat C, Laid Y, Lam T, Landrove O, Lanska V, Lappas G, Laxmaiah A, Leclercq C, Lee J, Lee J, Lehtimäki T, Lekhraj R, León-Muñoz L, Li Y, Lim W, Lima-Costa M, Lin H, Lin X, Lissner L, Lorbeer R, Lozano J, Luksiene D, Lundqvist A, Lytsy P, Ma G, Machado-Coelho G, Machi S, Maggi S, Magliano D, Makdisse M, Mallikharjuna Rao K, Manios Y, Manzato E, Margozzini P, Marques-Vidal P, Martorell R, Masoodi S, Mathiesen E, Matsha T, Mbanya J, McFarlane S, McGarvey S, McLachlan S, McNulty B, Mediene-Benchekor S, Meirhaeghe A, Menezes A, Merat S, Meshram I, Mi J, Miquel J, Miranda J, Mohamed M, Mohammad K, Mohammadifard N, Mohan V, Mohd Yusoff M, Møller N, Molnár D, Mondo C, Morejon A, Moreno L, Morgan K, Moschonis G, Mossakowska M, Mostafa A, Mota J, Motta J, Mu T, Muiesan M, Müller-Nurasyid M, Mursu J, Nagel G, Námešná J, Nang E, NangThetia V, Navarrete-Muñoz E, Ndiaye N, Nenko I, Nervi F, Nguyen N, Nguyen Q, Nieto-Martínez R, Ning G, Ninomiya T, Noale M, Noto D, Nsour M, Ochoa-Avilés A, Oh K, Onat A, Ordunez P, Osmond C, Otero J, Owusu-Dabo E, Pahomova E, Palmieri L, Panda-Jonas S, Panza F, Parsaeian M, Peixoto S, Pelletier C, Peltonen M, Peters A, Peykari N, Pham S, Pilav A, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubió P, Porta M, Portegies M, Poustchi H, Pradeepa R, Price J, Punab M, Qasrawi R, Qorbani M, Radisauskas R, Rahman M, Raitakari O, Rao S, Ramachandran A, Ramke J, Ramos R, Rampal S, Rathmann W, Redon J, Reganit P, Rigo F, Robinson S, Robitaille C, Rodríguez-Artalejo F, Rodriguez-Perez Mdel C, Rodríguez-Villamizar L, Rojas-Martinez R, Ronkainen K, Rosengren A, Rubinstein A, Rui O, Ruiz-Betancourt B, Russo Horimoto R, Rutkowski M, Sabanayagam C, Sachdev H, Saidi O, Sakarya S, Salanave B, Salonen J, Salvetti M, Sánchez-Abanto J, Santos D, dos Santos R, Santos R, Saramies J, Sardinha L, Sarrafzadegan N, Saum K, Scazufca M, Schargrodsky H, Scheidt-Nave C, Sein A, Sharma S, Shaw J, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai A, Simon M, Simons J, Simons L, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Snijder M, So H, Sobngwi E, Söderberg S, Solfrizzi V, Sonestedt E, Soumare A, Staessen J, Stathopoulou M, Steene-Johannessen J, Stehle P, Stein A, Stessman J, Stöckl D, Stokwiszewski J, Stronks K, Strufaldi M, Sun C, Sundström J, Sung Y, Suriyawongpaisal P, Sy R, Tai E, Tamosiunas A, Tang L, Tarawneh M, Tarqui-Mamani C, Taylor A, Theobald H, Thijs L, Thuesen B, Tolonen H, Tolstrup J, Topbas M, Torrent M, Traissac P, Trinh O, Tulloch-Reid M, Tuomainen T, Turley M, Tzourio C, Ueda P, Ukoli F, Ulmer H, Uusitalo H, Valdivia G, Valvi D, van Rossem L, van Valkengoed I, Vanderschueren D, Vanuzzo D, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren W, Verstraeten R, Viet L, Vioque J, Virtanen J, Visvikis-Siest S, Viswanathan B, Vollenweider P, Voutilainen S, Vrijheid M, Wade A, Wagner A, Walton J, Wan Mohamud W, Wang F, Wang M, Wang Q, Wang Y, Wannamethee S, Weerasekera D, Whincup P, Widhalm K, Wiecek A, Wijga A, Wilks R, Willeit J, Wilsgaard T, Wojtyniak B, Wong T, Woo J, Woodward M, Wu F, Wu S, Xu H, Yan W, Yang X, Ye X, Yoshihara A, Younger-Coleman N, Zambon S, Zargar A, Zdrojewski T, Zhao W, Zheng Y, Zuñiga Cisneros J. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants. The Lancet 2016, 387: 1513-1530. PMID: 27061677, PMCID: PMC5081106, DOI: 10.1016/s0140-6736(16)00618-8.Peer-Reviewed Original ResearchConceptsPopulation-based studyDiabetes prevalenceAdult prevalenceNumber of adultsOral hypoglycaemic drugsPrevalence of diabetesUse of insulinBurden of diabetesHigh national prevalenceNon-communicable diseasesTerms of prevalenceGlobal targetsHistory of diagnosisHypoglycaemic drugsCrude prevalenceMiddle-income countriesPooled analysisPlasma glucoseNational prevalenceHigh-income countriesDiabetes targetsDiabetesAdult womenPrevalenceWomen
2015
Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants
Danaei G, Fahimi S, Lu Y, Zhou B, Hajifathalian K, Di Cesare M, Lo W, Reis-Santos B, Cowan M, Shaw J, Bentham J, Lin J, Bixby H, Magliano D, Bovet P, Miranda J, Khang Y, Stevens G, Riley L, Ali M, Ezzati M, Abdeen Z, Kadir K, Abu-Rmeileh M, Acosta-Cazares B, Aekplakorn W, Aguilar-Salinas C, Ahmadvand A, Al Nsour M, Alkerwi A, Amouyel P, Andersen L, Anderssen S, Andrade D, Anjana R, Aounallah-Skhiri H, Aris T, Arlappa N, Arveiler D, Assah F, Avdicová M, Balakrishna N, Bandosz P, Barbagallo C, Barceló A, Batieha A, Baur L, Ben Romdhane H, Bernabe-Ortiz A, Bhargava S, Bi Y, Bjerregaard P, Björkelund C, Blake M, Blokstra A, Bo S, Boehm B, Boissonnet C, Bovet P, Brajkovich I, Breckenkamp J, Brewster L, Brian G, Bruno G, Bugge A, Cabrera de León A, Can G, Cândido A, Capuano V, Carvalho M, Casanueva F, Caserta C, Castetbon K, Chamukuttan S, Chaturvedi N, Chen C, Chen F, Chen S, Cheng C, Chetrit A, Chiou S, Cho Y, Chudek J, Cifkova R, Claessens F, Concin H, Cooper C, Cooper R, Costanzo S, Cottel D, Cowell C, Crujeiras A, D'Arrigo G, Dallongeville J, Dankner R, Dauchet L, de Gaetano G, De Henauw S, Deepa M, Dehghan A, Dhana K, Di Castelnuovo A, Djalalinia S, Doua K, Drygas W, Du Y, Egbagbe E, Eggertsen R, El Ati J, Elosua R, Erasmus R, Erem C, Ergor G, Eriksen L, Escobedo-de la Peña J, Fall C, Farzadfar F, Felix-Redondo F, Ferguson T, Fernández-Bergés D, Ferrari M, Ferreccio C, Finn J, Föger B, Foo L, Fouad H, Francis D, Franco Mdo C, Frontera G, Furusawa T, Gaciong Z, Galbarczyk A, Garnett S, Gaspoz J, Gasull M, Gates L, Geleijnse J, Ghasemain A, Giampaoli S, Gianfagna F, Giovannelli J, Gonzalez Gross M, González Rivas J, Gorbea M, Gottrand F, Grant J, Grodzicki T, Grøntved A, Gruden G, Gu D, Guan O, Guerrero R, Guessous I, Guimaraes A, Gutierrez L, Hardy R, Hari Kumar R, Heidemann C, Hihtaniemi I, Ho S, Ho S, Hofman A, Horimoto A, Hormiga C, Horta B, Houti L, Hussieni A, Huybrechts I, Hwalla N, Iacoviello L, Iannone A, Ibrahim M, Ikeda N, Ikram M, Irazola V, Islam M, Iwasaki M, Jacobs J, Jafar T, Jasienska G, Jiang C, Jonas J, Joshi P, Kafatos A, Kalter-Leibovici O, Kasaeian A, Katz J, Kaur P, Kavousi M, Kelishadi R, Kengne A, Kersting M, Khader Y, Khang Y, Kiechl S, Kim J, Kiyohara Y, Kolsteren P, Korrovits P, Koskinen S, Kratzer W, Kromhout D, Kula K, Kurjata P, Kyobutungi C, Lachat C, Laid Y, Lam T, Lanska V, Lappas G, Laxmaiah A, Leclercq C, Lee J, Lee J, Lehtimäki T, Lekhraj R, León-Muñoz L, Li Y, Lim W, Lima-Costa M, Lin H, Lin X, Lissner L, Lorbeer R, Lozano J, Lundqvist A, Lytsy P, Ma G, Machado-Coelho G, Machi S, Maggi S, Magliano D, Makdisse M, Mallikharjuna v K, Manios Y, Manzato E, Margozzini P, Marques-Vidal P, Martorell R, Masoodi S, Matsha T, Mbanya J, McFarlane S, McGarvey S, McLachlan S, McNulty B, Mediene-Benchekor S, Meirhaeghe A, Menezes A, Merat S, Meshram I, Mi J, Miquel J, Miranda J, Mohamed M, Mohammad K, Mohan V, Mohd Yusoff M, Møller N, Molnar D, Mondo C, Moreno L, Morgan K, Moschonis G, Mossakowska M, Mostafa A, Mota J, Muiesan M, Müller-Nurasyid M, Mursu J, Nagel G, Námešná J, Nang E, Nangia V, Navarrete-Muñoz E, Ndiaye N, Nervi F, Nguyen N, Nieto-Martínez R, Alvarado L, Ning G, Ninomiya T, Noale M, Noto D, Ochoa-Avilés M, Oh K, Onat A, Osmond C, Otero J, Palmieri L, Panda-Jonas S, Panza F, Parsaeian M, Peixoto S, Pereira A, Peters A, Peykari N, Pilav A, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubió P, Porta M, Portegies M, Poustchi H, Pradeepa R, Price J, Punab M, Qasrawi R, Qorbani M, Raitakari O, Ramachandra Rao S, Ramachandran A, Ramos R, Rampal S, Rathmann W, Redon J, Reganit P, Rigo F, Robinson S, Robitaille C, Rodríguez L, Rodríguez-Artalejo F, del Cristo Rodriguez-Perez M, Rojas-Martinez R, Romaguera D, Rosengren A, Rubinstein A, Rui O, Ruiz-Betancourt B, Rutkowski M, Sabanayagam C, Sachdev H, Saidi O, Sakarya S, Salanave B, Salonen J, Salvetti M, Sánchez-Abanto J, Santos R, Santos R, Sardinha L, Scazufca M, Schargrodsky H, Scheidt-Nave C, Shaw J, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai A, Simon M, Simons J, Simons L, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Snijder M, Solfrizzi V, Sonestedt E, Soumare A, Staessen J, Steene-Johannessen J, Stehle P, Stein A, Stessman J, Stöckl D, Stokwiszewski J, Strufaldi M, Sun C, Sundström J, Suriyawongpaisal P, Sy R, Tai E, Tarawneh M, Tarqui-Mamani C, Thijs L, Tolstrup J, Topbas M, Torrent M, Traissac P, Trinh O, Tulloch-Reid M, Tuomainen T, Turley M, Tzourio C, Ueda P, Ukoli F, Ulmer H, Valdivia G, van Valkengoed I, Vanderschueren D, Vanuzzo D, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren M, Vioque J, Virtanen J, Visvikis-Siest S, Viswanathan B, Vollenweider P, Voutilainen S, Wade A, Wagner A, Walton J, Mohamud W, Wang M, Wang Y, Wannamethee S, Weerasekera D, Whincup P, Widhalm K, Wiecek A, Wilks R, Willeit J, Wojtyniak B, Wong T, Woo J, Woodward M, Wu A, Wu F, Wu S, Xu H, Yang X, Ye X, Yoshihara A, Younger-Coleman N, Zambon S, Zargar A, Zdrojewski T, Zhao W, Zheng Y. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants. The Lancet Diabetes & Endocrinology 2015, 3: 624-637. PMID: 26109024, PMCID: PMC4673089, DOI: 10.1016/s2213-8587(15)00129-1.Peer-Reviewed Original ResearchConceptsHealth Examination SurveyPopulation prevalenceDiabetes prevalenceExamination SurveyPooled analysisPlasma glucoseUndiagnosed individualsOral glucose tolerance testDifferent biomarkersDifferent diagnostic definitionsPrevalence of diabetesPopulation-based studyGlucose tolerance testStudy-level characteristicsRandom-effects modelSimilar prevalence estimatesComplex survey designPrevious diagnosisUndiagnosed peopleTolerance testUS National InstitutesDiabetes definitionSources of heterogeneityHealth SurveyDifferent prevalence levelsMediators of the Effect of Body Mass Index on Coronary Heart Disease
Lu Y, Hajifathalian K, Rimm EB, Ezzati M, Danaei G. Mediators of the Effect of Body Mass Index on Coronary Heart Disease. Epidemiology 2015, 26: 153-162. PMID: 25643095, DOI: 10.1097/ede.0000000000000234.Peer-Reviewed Original ResearchConceptsBody mass indexCoronary heart diseaseExcess relative riskHigh-sensitive C-reactive proteinHigher body mass indexC-reactive proteinBlood pressureRelative riskMass indexBlood glucoseHeart diseaseRisk factorsMetabolic risk factorsProspective cohort studyPrevalence of overweightMajor risk factorRandom-effects modelProthrombotic biomarkersCHD eventsCohort studyInflammatory biomarkersObese participantsMetabolic mediatorsMetabolic factorsMultiplicative scale
2013
Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants
Lu Y, Hajifathalian K, Ezzati M, Woodward M, Rimm E, Danaei G. Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants. The Lancet 2013, 383: 970-983. PMID: 24269108, PMCID: PMC3959199, DOI: 10.1016/s0140-6736(13)61836-x.Peer-Reviewed Original ResearchConceptsBody mass indexCoronary heart diseaseHigher body mass indexHazard ratioBlood pressureExcess riskHeart diseaseEffect of BMIImperial College Healthcare NHS TrustMetabolic risk factorsProspective cohort studyAverage blood pressureHigh blood pressureCardiovascular disease preventionUK Medical Research CouncilNational InstituteRandom-effects modelMedical Research CouncilBiomedical Research CentreCohort studyProspective cohortStroke eventsNormal weightPooled analysisUS National Institutes
2011
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M, Group O. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants. The Lancet 2011, 378: 31-40. PMID: 21705069, DOI: 10.1016/s0140-6736(11)60679-x.Peer-Reviewed Original ResearchConceptsDiabetes prevalenceMean FPGHealth Examination SurveyExamination SurveyPlasma glucoseEpidemiological studiesHigh-income Asia PacificAge-specific prevalenceEffective preventive interventionsEffect of dietPerformance of interventionsLarge risePreventive interventionsHealth servicesFPGPrevalenceHealth systemDiabetesMelinda Gates FoundationWomenSmall riseGlycaemiaMenNumber of peopleSaharan Africa