2024
Group cohesion and alliance predict cognitive-behavioral group treatment outcomes for youth with anxiety disorders
Fjermestad K, Wallin M, Naujokat F, McLeod B, Silverman W, Öst L, Lerner M, Heiervang E, Wergeland G. Group cohesion and alliance predict cognitive-behavioral group treatment outcomes for youth with anxiety disorders. Cognitive Behaviour Therapy 2024, ahead-of-print: 1-19. PMID: 39105346, DOI: 10.1080/16506073.2024.2385906.Peer-Reviewed Original ResearchGroup cognitive behavioral therapyAnxiety disordersAnxiety symptomsDiagnostic recoveryParent-reported anxiety symptomsGroup cohesionCognitive behavioral therapyRandomized controlled effectiveness trialBehavioral therapyAlliance changeParent-reported outcomesEffectiveness trialClinical severityTreatment outcomesAnxietyPost-treatmentDisordersAllianceSymptomsYouthFollow-upGeneralized estimating equationsSeveritySessionsOutcomesAnxiety Symptom Trajectories Predict Depression Symptom Trajectories up to Four Years After CBT for Youth Anxiety Disorders
Fjermestad K, Norum F, Brask H, Kodal A, Silverman W, Heiervang E, Wergeland G. Anxiety Symptom Trajectories Predict Depression Symptom Trajectories up to Four Years After CBT for Youth Anxiety Disorders. Research On Child And Adolescent Psychopathology 2024, 52: 1503-1513. PMID: 38878114, PMCID: PMC11461661, DOI: 10.1007/s10802-024-01214-9.Peer-Reviewed Original ResearchCognitive behavioral therapyYouth anxiety disordersAnxiety symptom trajectoriesDepressive symptom trajectoriesDepressive symptomsSymptom trajectoriesParental mental healthAnxiety disordersAnxiety diagnosesMental healthDepression trajectoriesPost-cognitive behavioral therapyAssociated with less depressive symptomsSelf-reported depression levelsAnxiety symptom improvementDepression levelsParent-reported anxietyExamined depressive symptomsLess depressive symptomsGrowth curve modelsSelf-reported mental healthAssessment periodBehavioral therapyAnxiety trajectoriesDiagnostic recoveryPatterns of sub‐optimal change following CBT for childhood anxiety
Bertie L, Arendt K, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Heiervang E, In‐Albon T, Krause K, Lester K, Marin C, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Hudson J. Patterns of sub‐optimal change following CBT for childhood anxiety. Journal Of Child Psychology And Psychiatry 2024 PMID: 38817012, DOI: 10.1111/jcpp.14009.Peer-Reviewed Original ResearchCognitive behavioral therapyAnxiety disordersAnxiety diagnosesGrowth curve modelsMinimal respondersGroup cognitive behavioral therapyPatterns of symptom changeCurve modelClinically anxious youthSocial anxiety disorderAssociated with significantly less improvementResponse patternsAssess patterns of changeAnxious youthDisorder remissionChildhood anxietyMaternal psychopathologyBehavioral therapyDisorder severityDiagnostic statusSymptom changePre-and post-treatmentDelayed respondersAnxietyParental factorsChanges in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders
Gee D, Gunther K, Petrie D, Kitt E, Keding T, Broussard A, Zacharek S, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Odriozola P, Marin C, Silverman W, Lebowitz E. Changes in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders. Biological Psychiatry 2024, 95: s44. DOI: 10.1016/j.biopsych.2024.02.110.Peer-Reviewed Original ResearchFamily Accommodation in Anxious Irritable and Anxious Nonirritable Youth
Budagzad-Jacobson R, Musicaro R, Marin C, Silverman W, Lebowitz E. Family Accommodation in Anxious Irritable and Anxious Nonirritable Youth. Behavior Therapy 2024, 55: 913-921. PMID: 39174269, PMCID: PMC11341947, DOI: 10.1016/j.beth.2024.03.003.Peer-Reviewed Original ResearchFamily accommodationIrritable youthYouth anxietyParent ratingsCo-occurrence of anxietyLevels of irritabilityInfluence of irritabilityClinic-referredAnxiety disordersDiagnostic InterviewChild anxietyYouth ratingsAnxietyAccommodation behaviorAnxiety levelsTreatment targetModerating effectIrritability levelsYouthCo-occurrenceParentsIrritationDisordersFindingsAssociationResponding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety
Kitt E, Zacharek S, Odriozola P, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Broussard A, Dean J, Marin C, Silverman W, Lebowitz E, Gee D. Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety. Journal Of Affective Disorders 2024, 351: 818-826. PMID: 38290579, PMCID: PMC10981528, DOI: 10.1016/j.jad.2024.01.204.Peer-Reviewed Original ResearchConceptsReactivity to threatMeasures of avoidanceVentral anterior insulaClinician-based measuresNeural reactivityPediatric anxietyAnxiety disordersBehavioral avoidanceFunctional magnetic resonance imaging taskAmygdala functional connectivityVentromedial prefrontal cortexTreatment-seeking sampleAvoidance of threatClinically significant constructsAssociated with tasksGeneralizability of findingsPrefrontal cortexAnterior insulaNeural findingsLaboratory tasksFunctional connectivityAnxietyAmygdalaAvoidanceSignificant constructsNormalization of Fronto-Parietal Activation by Cognitive-Behavioral Therapy in Unmedicated Pediatric Patients With Anxiety Disorders
Haller S, Linke J, Grassie H, Jones E, Pagliaccio D, Harrewijn A, White L, Naim R, Abend R, Mallidi A, Berman E, Lewis K, Kircanski K, Fox N, Silverman W, Kalin N, Bar-Haim Y, Brotman M. Normalization of Fronto-Parietal Activation by Cognitive-Behavioral Therapy in Unmedicated Pediatric Patients With Anxiety Disorders. American Journal Of Psychiatry 2024, 181: 201-212. PMID: 38263879, PMCID: PMC11423803, DOI: 10.1176/appi.ajp.20220449.Peer-Reviewed Original ResearchCognitive-behavioral therapyAt-risk sampleAnxiety disordersWeeks of cognitive-behavioral therapyBlood oxygen level-dependent responsesFronto-parietal attention networkHealthy comparison youthFronto-parietal activityFronto-parietal networkRegional activity changesHealthy comparison childrenCBT effectsAt-riskTemperamental riskCognitive-behavioralLimbic responsesNeural differencesAnxiety patientsUnmedicated youthLimbic regionsTreatment-related changesSymptom changeComparison youthComparison childrenFunctional MRI
2023
Boundaries on Parent Involvement in Their Child’s Anxiety Cognitive-Behavioral-Treatment Outcome: Parent Reinforcement and Relationship Behaviors Moderate Outcome
Silverman W, Rey Y, Marin C, Boutris P, Jaccard J, Pettit J. Boundaries on Parent Involvement in Their Child’s Anxiety Cognitive-Behavioral-Treatment Outcome: Parent Reinforcement and Relationship Behaviors Moderate Outcome. Clinical Psychological Science 2023, 12: 936-944. PMID: 39474312, PMCID: PMC11521139, DOI: 10.1177/21677026231209331.Peer-Reviewed Original ResearchCognitive-behavioral treatmentParent reinforcementParents’ psychological controlPsychological controlCognitive behavioralRelationship behaviorsLower anxietyAnxiety disordersModeration effectPositive reinforcementParent involvementYouthAnxietyResearch replicationParentsModerate outcomeTrainingTreatment outcomesModeratorEfficacy trialsReinforcementChildrenOutcomesDisordersImplicationsDoes Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships?
Etkin R, Juel E, Lebowitz E, Silverman W. Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships? Clinical Child And Family Psychology Review 2023, 26: 1052-1076. PMID: 37838627, DOI: 10.1007/s10567-023-00454-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCognitive behavioral therapyAdolescent anxiety disordersPeer relationshipsSocial functioningAnxiety disordersYouth anxiety disordersPeer outcomesAnxiety reductionTreatment-specific effectsFunctioningTreatment specificitySystematic narrative reviewRelated difficultiesSample characteristicsMajority of studiesSpecific outcomesChildrenTreatment outcomesStatistical findingsStudy sampleDisordersNarrative reviewFindingsRelationshipAnxietyAffective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task
Nook E, Nardini C, Zacharek S, Hommel G, Spencer H, Martino A, Morra A, Flores S, Anderson T, Marin C, Silverman W, Lebowitz E, Gee D. Affective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task. Emotion 2023, 23: 1513-1521. PMID: 36595385, PMCID: PMC10314965, DOI: 10.1037/emo0001203.Peer-Reviewed Original ResearchConceptsNegative affect wordsChallenging puzzle taskAffect wordsAffective languagePuzzle taskEffective emotion regulationSpread of emotionsEmotion regulationNeuroscientific levelAnxious childrenEmotional influencesWord useBidirectional influenceAnxiety disordersBidirectional relationsMother's directionsMental healthEmotionsFuture researchWordsCurrent studyLanguageChildrenTaskMothers384. Cognitive Behavioral Therapy Normalizes Fronto-Parietal Activation in Unmedicated Patients With Pediatric Anxiety Disorders
Haller S, Linke J, Grassie H, Jones E, Pagliaccio D, Harrewijn A, White L, Naim R, Mallidi A, Berman E, Lewis K, Kircanski K, Silverman W, Kalin N, Bar-Haim Y, Brotman M. 384. Cognitive Behavioral Therapy Normalizes Fronto-Parietal Activation in Unmedicated Patients With Pediatric Anxiety Disorders. Biological Psychiatry 2023, 93: s249. DOI: 10.1016/j.biopsych.2023.02.624.Peer-Reviewed Original ResearchThe Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic
Kitt E, Cohodes E, McCauley S, Hommel G, Nardini C, Zacharek S, Martino A, Anderson T, Spencer H, Odriozola P, Spurrier G, Broussard A, Marin C, Silverman W, Lebowitz E, Gee D. The Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic. Journal Of Emotion And Psychopathology 2023, 1: 129-151. DOI: 10.55913/joep.v1i1.18.Peer-Reviewed Original ResearchCOVID-19-related fearCOVID-19-related stressFamily-level factorsAmygdala reactivityAnxiety disordersChildren's useEmotion regulation strategiesParent-child dynamicsExpressive suppressionAnxious youthFearful facesChildhood anxietyFMRI taskPediatric anxietyRegulation strategiesOwn functioningCOVID-19 pandemicFamily exposureMultimodal studyFearPervasive disruptionChildren's exposureFamily lifeParental assistanceAnxietyWhat is anxiety?
Musicaro R, Silverman W. What is anxiety? 2023, 219-226. DOI: 10.1016/b978-0-12-818872-9.00086-8.ChaptersChapter 19 Working with parents in the treatment of child and adolescent anxiety
Etkin R, Lebowitz E, Silverman W. Chapter 19 Working with parents in the treatment of child and adolescent anxiety. 2023, 341-358. DOI: 10.1016/b978-0-323-99613-6.00003-x.ChaptersAnxiety treatmentAdolescent anxietyAnxiety disordersChild anxiety treatmentIndividual child treatmentsAdolescent anxiety disordersExtant evidence baseParent variablesTreatment literatureChild's treatmentParent involvementParents' roleTreatment of childrenTheoretical importanceConsiderable methodological variationsEtiology of childrenMethodological variationsAnxietyParentsChildrenInvolvement approachEvidence baseValid inferencesConcrete recommendationsRich literature
2022
Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator
Patriarca G, Rey Y, Marin C, Yeguez C, Pettit J, Silverman W. Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator. Journal Of Consulting And Clinical Psychology 2022, 90: 827-836. PMID: 36355650, PMCID: PMC9727821, DOI: 10.1037/ccp0000770.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAnxiety outcomesParent acculturationAnxiety disordersPsychological controlNegative reinforcementEfficacy of CBTParents’ psychological controlYouth anxiety severityHispanic/Latino youthEvidence-based interventionsYouth ages 6Anxiety severityBehavioral treatmentParents' useLatino youthLatino familiesParent involvementAge 6YouthAcculturation levelAcculturationEnculturationModeratorDisordersMitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisordersПроведение когнитивно-поведенческой терапии с детьми и подростками с тревожными расстройствами
Patriarca G, Pettit J, Silverman W. Проведение когнитивно-поведенческой терапии с детьми и подростками с тревожными расстройствами. Clinical Psychology And Special Education 2022, 11: 108-122. PMID: 36474931, PMCID: PMC9720550, DOI: 10.17759/cpse.2022110207.Peer-Reviewed Original ResearchCognitive-behavioral treatmentAnxiety disordersCognitive-behavioral treatment approachCognitive-behavioral conceptualizationCognitive restructuringPhysiological arousalSeparation anxietySpecific phobiaTripartite modelBehavioral exposureBehavioral treatmentAvoidance behaviorPhases of treatmentAnxietyAdolescentsChildrenTreatment approachesEmotionsCognitionDisordersPhobiaArousalDifferent formatsConceptualizationGoal of treatmentYouth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome
Etkin RG, Marin CE, Silverman WK, Lebowitz ER. Youth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome. Behaviour Research And Therapy 2022, 156: 104160. PMID: 35870327, DOI: 10.1016/j.brat.2022.104160.Peer-Reviewed Original ResearchConceptsAnxiety treatment outcomesYouth social functioningSocial skillsPositive social interactionsSocial functioningAnxiety diagnosesAnxiety disordersSocial interactionParent-based treatmentChildren's social skillsSocial anxiety disorderYouths' social skillsAnxiety symptom severityYouth genderTreatment outcomesDiagnostic InterviewSymptom severityClinical functioningFunctioningSkillsYouthPredictorsMultiple regression modelDisordersGenderAnxiety and Social Functioning: The Moderating Roles of Family Accommodation and Youth Characteristics
Etkin RG, Silverman WK, Lebowitz ER. Anxiety and Social Functioning: The Moderating Roles of Family Accommodation and Youth Characteristics. Research On Child And Adolescent Psychopathology 2022, 50: 781-794. PMID: 34997402, DOI: 10.1007/s10802-021-00884-z.Peer-Reviewed Original ResearchConceptsYouth anxiety severityFamily accommodationAnxiety severitySocial functioningYouth anxietyAnxiety disordersSocial anxiety disorder diagnosisYouth ageSocial functioning difficultiesSocial anxiety disorderYouth social functioningAnxiety disorder diagnosisHierarchical linear regressionSocial functioning variablesAnxious youthTypes of difficultiesSocial impairmentFunctioning variablesPotential moderatorsModerating RoleIntervention effortsExtent of identificationFuture research directionsDepression symptomsAnxiety
2021
Moderators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis
Lebowitz ER, Zilcha‐Mano S, Orbach M, Shimshoni Y, Silverman WK. Moderators of response to child‐based and parent‐based child anxiety treatment: a machine learning‐based analysis. Journal Of Child Psychology And Psychiatry 2021, 62: 1175-1182. PMID: 33624848, DOI: 10.1111/jcpp.13386.Peer-Reviewed Original ResearchConceptsModerators of responseParent negativityChild anxiety treatmentOxytocin levelsBaseline anxietyCognitive behavioral therapyPrimary anxiety disorderChild-reported outcomesParent-reported outcomesChildhood anxietyAnxiety treatmentAnxiety symptomsPotential moderatorsAnxiety disordersTreatment conditionsModeratorMachine learning-based analysisAnxietyNegativitySignificant interactionChildrenNonoptimal treatmentTreatment efficacyParentingSocioemotional