Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort
He Q, Keding T, Zhang Q, Miao J, Russell J, Herringa R, Lu Q, Travers B, Li J. Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort. Journal Of Neurodevelopmental Disorders 2023, 15: 30. PMID: 37653373, PMCID: PMC10469494, DOI: 10.1186/s11689-023-09498-6.Peer-Reviewed Original ResearchConceptsADHD polygenic scoresDorsolateral prefrontal cortexADHD outcomesPolygenic scoresIA symptomsHyperactivity-impulsivity symptomsMultiple mediation modelIndirect effectsPhiladelphia Neurodevelopmental CohortBrain volumeInferior temporal lobeBrain-based biomarkersADHD inattentionGray matter volumeADHD symptomsHI symptomsMediation modelAngular gyrusNeurobiological mechanismsNeurodevelopmental CohortADHDPrefrontal cortexInattentionTemporal lobeBrain regions