Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology
Keding T, Heyn S, Russell J, Zhu X, Cisler J, McLaughlin K, Herringa R. Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology. American Journal Of Psychiatry 2021, 178: 1026-1036. PMID: 34407623, PMCID: PMC8570983, DOI: 10.1176/appi.ajp.2021.20081192.Peer-Reviewed Original ResearchConceptsChildhood abusePhysical neglectBrain Age Gap EstimationNormative brain developmentCircuit maturationBrain-wide patternsChildhood physical neglectEarly life adversityFronto-parietal cortexEmotion circuitsThreat generalizationGray matter volumePresence of psychopathologyResilient girlsLateral prefrontalHyperarousal symptomsInternalizing psychopathologyNeural contributorsAbused girlsInternalizing disorder diagnosesInternalizing diagnosesMaltreatment historyAbuse exposureAbuse historyNeurodevelopmental markers