2012
Altered Expression of Cytokine Signaling Pathway Genes in Peripheral Blood Cells of Alcohol Dependent Subjects: Preliminary Findings
Beech RD, Qu J, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R. Altered Expression of Cytokine Signaling Pathway Genes in Peripheral Blood Cells of Alcohol Dependent Subjects: Preliminary Findings. Alcohol Clinical And Experimental Research 2012, 36: 1487-1496. PMID: 22471388, PMCID: PMC3393821, DOI: 10.1111/j.1530-0277.2012.01775.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismBlood CellsCytokinesDemographyDiagnostic and Statistical Manual of Mental DisordersEthnicityFemaleGene ExpressionGene Expression ProfilingHumansInterleukin-15InterleukinsJanus KinasesMaleMicroarray AnalysisMiddle AgedRecurrenceSignal TransductionSTAT Transcription FactorsYoung AdultConceptsGroups of subjectsMD subjectsAlcohol dependenceGeneGo MetaCore softwareEnd-organ damageChronic alcohol abusePeripheral blood cellsInnate immune responseAlcohol-dependent subjectsHeavy alcohol useT cell receptorPeripheral bloodClinical studiesImmune responseJanus kinase-signal transducerHigh riskImmune functionModerate drinkersHD subjectsAlcohol abuseAlcohol consumptionHeavy drinkersKinase-signal transducerDependent subjectsSignaling Pathway Genes
2011
Spatio-temporal transcriptome of the human brain
Kang HJ, Kawasawa YI, Cheng F, Zhu Y, Xu X, Li M, Sousa AM, Pletikos M, Meyer KA, Sedmak G, Guennel T, Shin Y, Johnson MB, Krsnik Ž, Mayer S, Fertuzinhos S, Umlauf S, Lisgo SN, Vortmeyer A, Weinberger DR, Mane S, Hyde TM, Huttner A, Reimers M, Kleinman JE, Šestan N. Spatio-temporal transcriptome of the human brain. Nature 2011, 478: 483-489. PMID: 22031440, PMCID: PMC3566780, DOI: 10.1038/nature10523.Peer-Reviewed Original Research
2010
Increased peripheral blood expression of electron transport chain genes in bipolar depression
Beech RD, Lowthert L, Leffert JJ, Mason PN, Taylor MM, Umlauf S, Lin A, Lee JY, Maloney K, Muralidharan A, Lorberg B, Zhao H, Newton SS, Mane S, Epperson CN, Sinha R, Blumberg H, Bhagwagar Z. Increased peripheral blood expression of electron transport chain genes in bipolar depression. Bipolar Disorders 2010, 12: 813-824. PMID: 21176028, PMCID: PMC3076072, DOI: 10.1111/j.1399-5618.2010.00882.x.Peer-Reviewed Original ResearchConceptsBipolar disorderBipolar depressionPeripheral bloodDepressed subjectsGeneGo MetaCore softwarePeripheral blood expressionHealthy control subjectsReal-time reverse transcription-polymerase chain reactionEffects of medicationReverse transcription-polymerase chain reactionQuantitative real-time reverse transcription-polymerase chain reactionTranscription-polymerase chain reactionMitochondrial electron transport chainControl subjectsPolymerase chain reactionUnmedicated subjectsHealthy controlsBlood expressionBPD subjectsSpecific genetic pathwaysElectron transport chain genesMetaCore softwareA totalAltered expressionQRT-PCR