2019
Collisions on the Busy DNA Highway Set Up Barriers for Reprogramming
Hu X, Guo S. Collisions on the Busy DNA Highway Set Up Barriers for Reprogramming. Cell Stem Cell 2019, 25: 451-453. PMID: 31585090, DOI: 10.1016/j.stem.2019.09.007.Peer-Reviewed Original ResearchTargeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing.
Hetzler PT, Dash BC, Guo S, Hsia HC. Targeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing. Annals Of Plastic Surgery 2019, 83: e92-e95. PMID: 31246672, PMCID: PMC6851445, DOI: 10.1097/sap.0000000000001955.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCell SurvivalCells, CulturedFemaleFibrosisGene Expression RegulationHumansMaleMyofibroblastsSignal TransductionTranslational Research, BiomedicalWound HealingConceptsTherapeutic targetAberrant wound healing processAppropriate physiologic responseMorbid disease processSurvival of myofibroblastsWound healingFibrotic signaling pathwaysTranscription factor/serum response factor (MRTF/SRF) pathwayFuture therapeutic targetsSmooth muscle actinFuture translational researchCurrent literatureFibrotic signalingTherapeutic optionsFibrotic lesionsTissue injuryWound healing processDisease processPhysiologic responsesSerum response factor pathwayMuscle actinFactor pathwayExcessive responseFibrosisTranslational research
2008
MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors
Lu J, Guo S, Ebert BL, Zhang H, Peng X, Bosco J, Pretz J, Schlanger R, Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, Golub TR. MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors. Developmental Cell 2008, 14: 843-853. PMID: 18539114, PMCID: PMC2688789, DOI: 10.1016/j.devcel.2008.03.012.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CD34Bone Marrow CellsCell DifferentiationCell LineageCells, CulturedErythroid CellsErythropoietinGene Expression RegulationGenes, ReporterHematopoietic Stem CellsHumansIntegrin beta3K562 CellsMegakaryocytesMiceMice, Inbred C57BLMicroRNAsModels, BiologicalPlatelet Membrane Glycoprotein IIbProto-Oncogene Proteins c-mybThrombopoietinConceptsMegakaryocyte-erythrocyte progenitorsLineage specificationTranscription factor MYBMiR-150Cell fateLineage fateRegenerative biologyErythroid cellsFunction experimentsMultipotent cellsMegakaryocytic lineageMiRNA expressionPrimary cellsCritical targetModel systemMicroRNAsProgenitorsFateRegulationCellsImportant participantsMYBLineagesMiRNAsBiology