Featured Publications
Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19
Cohen A, Glick L, Lee S, Kunitomo Y, Tsang D, Pitafi S, Toro P, Ristic N, Zhang E, Carey G, Datta R, Dela Cruz C, Gautam S. Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19. European Clinical Respiratory Journal 2023, 10: 2174640. PMID: 36815942, PMCID: PMC9930745, DOI: 10.1080/20018525.2023.2174640.Peer-Reviewed Original ResearchSevere COVID-19Bacterial superinfectionBacterial pneumoniaCOVID-19Lower respiratory culturesSuperimposed bacterial pneumoniaUtility of procalcitoninProcalcitonin measurementImmune biomarkersClinical resemblanceRespiratory culturesImmunomodulatory agentsProcalcitoninPatientsBacterial infectionsSuperinfectionCurve analysisSignificant riskCharacteristic curvePneumoniaTime of cultureDiagnosisInfectionBiomarkersWall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus
Gautam S, Kim T, Lester E, Deep D, Spiegel DA. Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus. ACS Chemical Biology 2015, 11: 25-30. PMID: 26502318, PMCID: PMC5592732, DOI: 10.1021/acschembio.5b00439.Peer-Reviewed Original Research
2022
Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer
Lee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer. Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e152. PMID: 36483405, PMCID: PMC9726473, DOI: 10.1017/ash.2022.293.Peer-Reviewed Original Research
2021
Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report
Dela Cruz CS, Evans SE, Restrepo MI, Dean N, Torres A, Amara-Elori I, Awasthi S, Caler E, Cao B, Chalmers JD, Chastre J, Cohen TS, Cohen AH, Crothers K, Di YP, Egan ME, Feldman C, Gautam S, Halstead ES, Herold S, Jones BE, Luna C, Niederman MS, Mendez R, Menendez R, Mizgerd JP, Nusrat R, Ramirez J, Shindo Y, Waterer G, Yeligar SM, Wunderink RG. Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2021, 18: 1087-1097. PMID: 34242148, PMCID: PMC8328365, DOI: 10.1513/annalsats.202102-209st.BooksConceptsLung infectionOfficial American Thoracic Society Workshop ReportAmerican Thoracic Society meetingLong-term health outcomesRisk of pneumoniaHost risk factorsManagement of pneumoniaExtremes of ageClinical practice guidelinesTreatment of pneumoniaInnovative trial designsPneumonia pathogenesisCritical illnessPulmonary infectionImmunosuppressive disordersPneumonia therapyOutcome definitionsRisk factorsClinical trialsPractice guidelinesRespiratory diseasePneumoniaPneumonia StudySystemic effectsTrial design
2019
Teaching an Old Intensivist Neutrophil Tricks: Using Alveolar Neutrophilia to Diagnose Ventilator-associated Pneumonia
Gautam S, Sharma L, Dela Cruz CS. Teaching an Old Intensivist Neutrophil Tricks: Using Alveolar Neutrophilia to Diagnose Ventilator-associated Pneumonia. American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1178-1181. PMID: 30543457, PMCID: PMC6519853, DOI: 10.1164/rccm.201811-2163ed.Commentaries, Editorials and Letters
2018
Personalizing the Management of Pneumonia
Gautam S, Sharma L, Dela Cruz CS. Personalizing the Management of Pneumonia. Clinics In Chest Medicine 2018, 39: 871-900. PMID: 30390755, DOI: 10.1016/j.ccm.2018.08.008.Books