2001
Case control and family‐based studies of tryptophan hydroxylase gene A218C polymorphism and suicidality in adolescents
Zalsman G, Frisch A, King R, Pauls D, Grice D, Gelernter J, Alsobrook J, Michaelovsky E, Apter A, Tyano S, Weizman A, Leckman J. Case control and family‐based studies of tryptophan hydroxylase gene A218C polymorphism and suicidality in adolescents. American Journal Of Medical Genetics 2001, 105: 451-457. PMID: 11449398, DOI: 10.1002/ajmg.1406.Peer-Reviewed Original ResearchConceptsSuicidal behaviorSuicide riskA218C polymorphismDetailed clinical historyHaplotype relative riskAssociation of suicidalityTransmission disequilibrium test (TDT) methodsTryptophan hydroxylase geneAdolescent suicidal behaviorClinical historySame ethnic populationRelative riskCase controlAA genotypeControl groupFamily-based studySuicide intentSignificant allelic associationSignificant differencesEthnic populationsStructured interviewsInpatient adolescentsRiskAssociationSuicidality
1997
Children's Yale-Brown Obsessive Compulsive Scale: Reliability and Validity
Scahill L, Riddle M, McSwiggin-Hardin M, Ort S, King R, Goodman W, Cicchetti D, Leckman J. Children's Yale-Brown Obsessive Compulsive Scale: Reliability and Validity. Journal Of The American Academy Of Child & Adolescent Psychiatry 1997, 36: 844-852. PMID: 9183141, DOI: 10.1097/00004583-199706000-00023.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent PsychiatryChildChild PsychiatryFemaleHumansMaleObsessive-Compulsive DisorderPsychiatric Status Rating ScalesReproducibility of ResultsConceptsChildren's Yale-Brown Obsessive Compulsive ScaleYale-Brown Obsessive Compulsive ScaleObsessive-compulsive disorderObsessive-compulsive symptom severityManifest Anxiety ScaleObsessive-compulsive symptomsObsessive Compulsive ScaleChildren's Manifest Anxiety ScaleCompulsive ScaleCY-BOCS total scoreSymptom severityDepression InventoryChildren's Depression InventoryTotal scoreCY-BOCS scoresAnxiety ScaleConvergent validityValid subscalesInternal consistencyCompulsion scoreAdolescentsSubscalesChildrenInterrater agreementValidity
1996
Behavioral Therapy in Children and Adolescents with Obsessive-Compulsive Disorder: A Pilot Study
Scahill L, Vitulano L, Brenner E, Lynch K, King R. Behavioral Therapy in Children and Adolescents with Obsessive-Compulsive Disorder: A Pilot Study. Journal Of Child And Adolescent Psychopharmacology 1996, 6: 191-202. PMID: 9231312, DOI: 10.1089/cap.1996.6.191.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleBehavioral treatmentBehavioral therapyRandomized clinical trialsTreatment of childrenChildren's Yale-Brown Obsessive Compulsive ScaleBehavioral therapy programObsessive Compulsive ScaleMedication treatmentPrimary diagnosisMonths posttreatmentClinical trialsTreatment endpointBooster sessionsDose reductionDose requirementsMedicationsUseful adjunctTherapeutic gainTreatment programTherapy programPilot studyCompulsive ScaleTreatment
1995
Childhood Trichotillomania: Clinical Phenomenology, Comorbidity, and Family Genetics
KING R, SCAHILL L, VITULANO L, SCHWAB-STONE M, TERCYAK K, RIDDLE M. Childhood Trichotillomania: Clinical Phenomenology, Comorbidity, and Family Genetics. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1451-1459. PMID: 8543512, DOI: 10.1097/00004583-199511000-00011.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildFemaleHumansMaleObsessive-Compulsive DisorderPsychiatric Status Rating ScalesSeverity of Illness IndexTic DisordersTrichotillomaniaConceptsObsessive-compulsive disorderAn Epidemiological Study of Trichotillomania in Israeli Adolescents
KING R, ZOHAR A, RATZONI G, BINDER M, KRON S, DYCIAN A, COHEN D, PAULS D, APTER A. An Epidemiological Study of Trichotillomania in Israeli Adolescents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1212-1215. PMID: 7559316, DOI: 10.1097/00004583-199509000-00019.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAttention Deficit Disorder with HyperactivityFemaleHumansIncidenceIsraelMaleObsessive-Compulsive DisorderPrevalencePsychiatric Status Rating ScalesTrichotillomaniaConceptsObsessive-compulsive symptomsComorbid psychopathologyPrevalence of trichotillomaniaSignificant obsessive-compulsive symptomsObsessive-compulsive disorderLifetime prevalenceVocal ticsComorbid disordersEpidemiological studiesPrevalenceAnxiety disordersPhysical fitnessSubsequent reliefTrichotillomaniaCommunity adolescent sampleDisordersSymptomsElevated ratesOverall competencySubjectsAdolescentsReliefPsychopathologyBald spotsIsraeli adolescents
1994
Fluvoxamine Open-Label Treatment of Adolescent Inpatients with Obsessive-Compulsive Disorder or Depression
APTER A, RATZONI G, KING R, WEIZMAN A, IANCU I, BINDER M, RIDDLE M. Fluvoxamine Open-Label Treatment of Adolescent Inpatients with Obsessive-Compulsive Disorder or Depression. Journal Of The American Academy Of Child & Adolescent Psychiatry 1994, 33: 342-348. PMID: 8169178, DOI: 10.1097/00004583-199403000-00007.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMajor depressive disorderYale-Brown Obsessive Compulsive ScaleOvert Aggression ScaleBeck Depression InventorySide effectsSuicide Potential ScaleSpecific serotonin uptake inhibitorAdolescent inpatientsEfficacy of fluvoxamineOpen-label trialOpen-label treatmentCommon side effectsSerotonin uptake inhibitorSerious side effectsShort-term treatmentY-BOCS scoresObsessive Compulsive ScaleDaily dosesTarget symptomsDepressive disorderDemonstrated efficacyInvestigational basisUptake inhibitorFluvoxamine