2018
GaMRed—Adaptive Filtering of High-Throughput Biological Data
Marczyk M, Jaksik R, Polanski A, Polanska J. GaMRed—Adaptive Filtering of High-Throughput Biological Data. IEEE/ACM Transactions On Computational Biology And Bioinformatics 2018, 17: 149-157. PMID: 30040660, DOI: 10.1109/tcbb.2018.2858825.Peer-Reviewed Original ResearchConceptsSensitivity of methodsGaussian mixture decompositionError rateHigh-throughput biological experimentsUnchanged signalsSignal level
2017
Improving Peak Detection by Gaussian Mixture Modeling of Mass Spectral Signal
Marczyk M, Polanska J, Polanski A. Improving Peak Detection by Gaussian Mixture Modeling of Mass Spectral Signal. 2017, 39-43. DOI: 10.1109/icfsp.2017.8097057.Peer-Reviewed Original Research
2013
Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition
Marczyk M, Jaksik R, Polanski A, Polanska J. Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition. BMC Bioinformatics 2013, 14: 101. PMID: 23510016, PMCID: PMC3637832, DOI: 10.1186/1471-2105-14-101.Peer-Reviewed Original ResearchConceptsGaussian mixture decompositionFalse discoveriesMicroarray gene expression dataNon-informative genesAdaptive filteringSample meanAdaptive methodSample varianceGaussian componentsMixture decompositionGene filteringEarlier paperGene expression dataFilteringOptimal threshold valuePrevious methodsMicroarray experimentsNew methodTwo-step procedureThreshold valueCorrection methodPower of detectionImportant parametersSecond stepMicroarray data