2024
Quality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial
Park D, Jamil Y, Moumneh M, Batchelor B W, Nanna M, Damluji A. Quality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial. The American Journal Of Cardiology 2024, 223: 58-69. PMID: 38797195, PMCID: PMC11214881, DOI: 10.1016/j.amjcard.2024.05.016.Peer-Reviewed Original ResearchDuke Activity Status IndexOlder adultsYears of follow-upStable ischemic heart diseaseIntensive medical therapyQoL measuresStatus indexIschemic heart diseaseDistress ratingsOlder adult populationOlder adult patientsBARI 2D trialDiabetes mellitusQuality of lifeQuality-of-lifeHeart diseaseMultivariate linear regressionFollow-upMedical therapyAdult populationQoLCognitive impairmentOlder patientsPost hoc analysisChronic total occlusion
2023
Beyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease
Kalra K, Moumneh M, Nanna M, Damluji A. Beyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease. Frontiers In Cardiovascular Medicine 2023, 10: 1276370. PMID: 38045910, PMCID: PMC10690830, DOI: 10.3389/fcvm.2023.1276370.Peer-Reviewed Original ResearchStable ischemic heart diseaseIschemic heart diseaseClinical trialsOlder adult populationOlder adultsHeart diseaseHealth outcomesAdult populationMajor adverse cardiovascular outcomesHigh cardiovascular riskAdverse cardiovascular outcomesMultiple chronic diseasesPatient-centered approachCardiovascular clinical trialsPoor health outcomesMore effective careQuality of lifeHolistic health outcomesCardiovascular outcomesCardiovascular riskGeriatric syndromesRandomized trialsPatient populationPatient preferencesChronic diseasesLife’s Essential 8 Optimizing Health in Older Adults
Kumar M, Orkaby A, Tighe C, Villareal D, Billingsley H, Nanna M, Kwak M, Rohant N, Patel S, Goyal P, Hummel S, Al-Malouf C, Kolimas A, Krishnaswami A, Rich M, Kirkpatrick J, Damluji A, Kuchel G, Forman D, Alexander K. Life’s Essential 8 Optimizing Health in Older Adults. JACC Advances 2023, 2: 100560. PMID: 37664644, PMCID: PMC10470487, DOI: 10.1016/j.jacadv.2023.100560.Peer-Reviewed Original ResearchClinical cardiovascular diseaseOlder adultsPrevention targetsTraditional CVD risk factorsCVD-free survivalCVD risk factorsGoals of careAmerican Heart AssociationQuality of lifeGeriatric syndromesHeart AssociationRisk factorsCardiovascular diseaseHigh prevalenceCell exhaustionChronologic ageSleep healthOlder individualsMitochondrial dysfunctionStem cell exhaustionResult of advancesCellular senescenceAdultsPublic healthIntercellular communicationD-24 | Quality of Life After Revascularization versus Medical Therapy in Older Adults With Stable Ischemic Heart Disease at 5 Year Follow-up in the BARI2D Trial
Park D, Jamil Y, Chongthammakun V, Nanna M, Al Damluji A. D-24 | Quality of Life After Revascularization versus Medical Therapy in Older Adults With Stable Ischemic Heart Disease at 5 Year Follow-up in the BARI2D Trial. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 100878. DOI: 10.1016/j.jscai.2023.100878.Peer-Reviewed Original Research
2021
The prospective randomized trial of the optimal evaluation of cardiac symptoms and revascularization: Rationale and design of the PRECISE trial
Nanna MG, Vemulapalli S, Fordyce CB, Mark DB, Patel MR, Al-Khalidi HR, Kelsey M, Martinez B, Yow E, Mullen S, Stone GW, Ben-Yehuda O, Udelson JE, Rogers C, Douglas PS. The prospective randomized trial of the optimal evaluation of cardiac symptoms and revascularization: Rationale and design of the PRECISE trial. American Heart Journal 2021, 245: 136-148. PMID: 34953768, PMCID: PMC8979644, DOI: 10.1016/j.ahj.2021.12.004.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseStable chest painChest painDiagnostic strategiesUsual careCardiac symptomsMajor adverse cardiac eventsNon-acute chest painObstructive coronary artery diseaseInitial diagnostic strategyInvasive cardiac catheterizationUse of CCTAUsual care strategyAdverse cardiac eventsProspective randomized trialsClinical care teamFractional flow reserveQuality of lifeHealth care costsOptimal evaluationPrimary endpointRevascularization TrialSecondary endpointsCardiac eventsArtery disease