2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfectionNeonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci
Bizzarro MJ, Shabanova V, Baltimore RS, Dembry LM, Ehrenkranz RA, Gallagher PG. Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci. The Journal Of Pediatrics 2015, 166: 1193-1199. PMID: 25919728, PMCID: PMC4413005, DOI: 10.1016/j.jpeds.2015.02.009.Peer-Reviewed Original ResearchConceptsEarly-onset sepsisLate-onset sepsisNeonatal intensive care unitCoagulase-negative staphylococciIntensive care unitCare unitLevel IV neonatal intensive care unitEpisodes of sepsisLow birth weightInfection prevention initiativesInfection prevention effortsPercent of casesGroup B streptococciHospital courseSepsis episodesMost infantsBirth weightCommon organismB streptococciSepsisOutcome dataAdditional surveillancePrevention effortsStudy periodInfants
2014
Ear drainage and the role of sepsis evaluations in the neonatal intensive care unit
Khattab M, Cannon‐Heinrich C, Bizzarro MJ. Ear drainage and the role of sepsis evaluations in the neonatal intensive care unit. Acta Paediatrica 2014, 103: 732-736. PMID: 24635016, PMCID: PMC4320968, DOI: 10.1111/apa.12636.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitEar drainageSepsis evaluationCare unitTape removalMedian gestational ageExternal auditory canalGestational ageAuditory canalInflammatory processUnnecessary interventionsAnti-adhesive productDrainageInterventionEarOnsetBirthweightAdmissionCasesEvaluationWeeksClinical and Laboratory Factors That Predict Death in Very Low Birth Weight Infants Presenting With Late-onset Sepsis
Levit O, Bhandari V, Li FY, Shabanova V, Gallagher PG, Bizzarro MJ. Clinical and Laboratory Factors That Predict Death in Very Low Birth Weight Infants Presenting With Late-onset Sepsis. The Pediatric Infectious Disease Journal 2014, 33: 143-146. PMID: 24418836, PMCID: PMC3917323, DOI: 10.1097/inf.0000000000000024.Peer-Reviewed Original ResearchConceptsLate-onset sepsisLow birth weight infantsBirth weight infantsIndependent risk factorLaboratory factorsWeight infantsVLBW infantsRisk factorsCases of LOSEpisodes of LOSRisk of LOSFungal LOSNeonatal intensive care unitMultivariate logistic regression analysisSepsis-related deathsIntensive care unitOnset of illnessSepsis-associated mortalityGram-positive infectionsLogistic regression analysisOnset of diseasePresentation of illnessComposite risk profileLaboratory signsNecrotizing enterocolitis
2013
Concurrent Bloodstream Infections in Infants with Necrotizing Enterocolitis
Bizzarro MJ, Ehrenkranz RA, Gallagher PG. Concurrent Bloodstream Infections in Infants with Necrotizing Enterocolitis. The Journal Of Pediatrics 2013, 164: 61-66. PMID: 24139563, DOI: 10.1016/j.jpeds.2013.09.020.Peer-Reviewed Original ResearchConceptsBloodstream infectionsPost-NECNegative bacilliLate-onset bloodstream infectionConcurrent bloodstream infectionHospital course dataMean gestational ageCases of NECDiagnosis of NECOnset of diseaseMicrobiologic etiologyUnderappreciated complicationMicrobiologic dataNecrotizing enterocolitisGestational ageRetrospective reviewSingle centerSurgical interventionBirth weightRisk factorsHigher oddsInfantsNECEnterocolitisInfectionTemporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit
Bizzarro MJ, Li FY, Katz K, Shabanova V, Ehrenkranz RA, Bhandari V. Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit. Journal Of Perinatology 2013, 34: 33-38. PMID: 24071904, DOI: 10.1038/jp.2013.122.Peer-Reviewed Original ResearchConceptsSevere ROPRetinopathy of prematurityNeonatal intensive care unitIntensive care unitCare unitMultivariate analysisBronchopulmonary dysplasia/deathTarget saturation rangePost-intervention evaluationPreterm neonatesOxygen saturationStaff educationSurgeryInfantsMultidisciplinary groupSignificant reductionHyperoxiaDeathExposureSignal extraction technologyMorbidityPrematurityRetinopathyNeonatesNeutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis
Streimish I, Bizzarro M, Northrup V, Wang C, Renna S, Koval N, Li FY, Ehrenkranz RA, Rinder HM, Bhandari V. Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis. American Journal Of Perinatology 2013, 31: 021-030. PMID: 23456906, DOI: 10.1055/s-0033-1334453.Peer-Reviewed Original ResearchConceptsCulture-proven sepsisClinical sepsisNeutrophil CD64CD64 indexNeonatal sepsisHematologic criteriaSingle-centre neonatal intensive care unitEarly-onset clinical sepsisNeonatal intensive care unitNeutrophil CD64 indexProspective observational cohortAbsolute neutrophil countNormal birth weightIntensive care unitAbsolute band countNegative predictive valueAdditional markersSepsis evaluationNeutrophil countObservational cohortCare unitBirth weightHematologic parametersSepsisCD64
2010
Who is performing medical procedures in the neonatal intensive care unit?
Gozzo Y, Cummings C, Chapman R, Bizzarro M, Mercurio M. Who is performing medical procedures in the neonatal intensive care unit? Journal Of Perinatology 2010, 31: 206-211. PMID: 21052046, DOI: 10.1038/jp.2010.121.Peer-Reviewed Original Research
2009
Selective resuscitation in premature twins: an ethical analysis
Bizzarro M, Mercurio M. Selective resuscitation in premature twins: an ethical analysis. Journal Of Perinatology 2009, 29: 479-482. PMID: 19556982, PMCID: PMC2834502, DOI: 10.1038/jp.2009.44.Peer-Reviewed Original Research