1999
Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation
Müschen M, Warskulat U, Peters-Regehr T, Bode J, Kubitz R, Häussinger D. Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation. Gastroenterology 1999, 116: 666-677. PMID: 10029626, DOI: 10.1016/s0016-5085(99)70189-7.Peer-Reviewed Original ResearchConceptsMessenger RNA levelsKupffer cellsT lymphocytesRat Kupffer cellsRNA levelsInterferon gammaLigand expressionImmune-privileged organQuantitative reverse transcription polymerase chain reactionReverse transcription-polymerase chain reactionReceptor/ligand systemCD95 receptor/ligand systemEnzyme-linked immunosorbent assayCD95 ligand expressionCD95 receptorHepatic immunoregulationPolymerase chain reactionSoluble CD95Inflammatory responseLymphocytesAbstractTextCyclosporin AImmunosorbent assayParenchymal cellsGamma treatment
1998
Regulation of CD95 (APO‐1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells
Müschen M, Warskulat U, Douillard P, Gilbert E, Häussinger D. Regulation of CD95 (APO‐1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells. Hepatology 1998, 27: 200-208. PMID: 9425938, DOI: 10.1002/hep.510270131.Peer-Reviewed Original ResearchConceptsSinusoidal endothelial cellsNumber of KCsCD95L mRNA levelsKupffer cellsParenchymal cellsMRNA levelsNonparenchymal rat liver cellsNonparenchymal cellsCD95L expressionEffects of lipopolysaccharideMeans of immunocytochemistryLiver Kupffer cellsAddition of supernatantsPresence of lipopolysaccharideLiver cell populationsRat liver Kupffer cellsMessenger RNA levelsCD95 receptorLPS treatmentRat liver cellsThymic lymphocytesCD95 expressionLigand expressionLPS additionPrimary hepatocyte cultures