Transcriptional Regulatory Landscape of TCF3-PBX1-Positive Leukemia and Novel Targeted Treatments
Teppo S, Mehtonen J, Eldfors S, Heckman C, Müschen M, Heinäniemi M, Lohi O. Transcriptional Regulatory Landscape of TCF3-PBX1-Positive Leukemia and Novel Targeted Treatments. Blood 2016, 128: 4077. DOI: 10.1182/blood.v128.22.4077.4077.Peer-Reviewed Original ResearchTranscriptional regulatory landscapeTranscription factorsRegulatory landscapeCell line modelsFusion proteinGenome-wide mapsGlobal nuclear runNovel long non-coding RNANetwork inference analysisDruggable targetsLong non-coding RNAsGene expression differencesNon-coding RNAsGene Expression OmnibusGRO-seq analysisTumor suppressor genePBX1 functionsNovel drug targetsNascent transcriptionTranscriptional landscapeEnhancer RNAsGenomic regionsGRO-seqNetwork inference algorithmsExpression differences