2024
An adapted scale to measure perceived TB and HIV stigma during household contact investigation.
Armstrong-Hough M, Shelby T, Ggita J, Nangendo J, Gupta A, Davis J, Katamba A. An adapted scale to measure perceived TB and HIV stigma during household contact investigation. The International Journal Of Tuberculosis And Lung Disease 2024, 28: 433-438. PMID: 39187997, DOI: 10.5588/ijtld.23.0395.Peer-Reviewed Original ResearchConceptsHousehold contact investigationStigma ScaleTB-HIVNewly diagnosed TB patientsContact investigationCognitive interview dataHIV stigmaHealth behaviorsFactor analysisCognitive interviewsElimination of itemsInter-item covariationStandardised measuresPsychometric propertiesRandom sampleTB patientsInterview dataHIVIdentifying opportunitiesStigmaHousehold contactsItemsScoresHouseholdsCovariatesLung function and health-related quality of life among adult patients following pulmonary TB treatment.
Zawedde J, Abelman R, Musisi E, Nyabigambo A, Sanyu I, Kaswabuli S, Byanyima P, Lewis E, Sessolo A, Lalitha R, Kiwanuka N, Crothers K, Worodria W, Davis J, Huang L. Lung function and health-related quality of life among adult patients following pulmonary TB treatment. The International Journal Of Tuberculosis And Lung Disease 2024, 28: 419-426. PMID: 39187999, DOI: 10.5588/ijtld.24.0029.Peer-Reviewed Original ResearchConceptsSt. George's Respiratory QuestionnaireQuality of lifeAbnormal lung functionSpirometric restrictionHealth-related quality of lifeLung functionPost-TB lung diseaseHealth-related qualityFemale sexRisk factorsFunctional abnormalitiesGeorge's Respiratory QuestionnairePTB treatmentPulmonary TB treatmentAssociated with increased morbidityChronic lung complicationsPrevalence ratiosResource-limited settingsChest X-rayLung function abnormalitiesRespiratory QuestionnaireSGRQ scoreAssociated with lung function abnormalitiesSmoking statusBilateral consolidation
2023
A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial
Katamba A, Gupta A, Turimumahoro P, Ochom E, Ggita J, Nakasendwa S, Nanziri L, Musinguzi J, Hennein R, Sekadde M, Hanrahan C, Byaruhanga R, Yoeli E, Turyahabwe S, Cattamanchi A, Dowdy D, Haberer J, Armstrong-Hough M, Kiwanuka N, Davis J. A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial. BMC Public Health 2023, 23: 1568. PMID: 37592314, PMCID: PMC10436440, DOI: 10.1186/s12889-023-16510-0.Peer-Reviewed Original ResearchConceptsContact investigationClinical effectiveness outcomesPrimary implementation outcomeTB contact investigationTB preventative therapyTB treatment initiationTimely TB diagnosisTrial registrationThe trialTuberculosis contact investigationCluster-randomised trialHigh-burden settingsImplementation-effectiveness trialEvidence-based interventionsUganda National CouncilWorld Health OrganizationProportion of contactsTB evaluationPeer-reviewed journalsMiddle-income countriesTreatment initiationTB diagnosisPreventative therapyUndiagnosed personsInfectious deathSputum samplesExploring stakeholders perspectives on TB contact investigation in Cali, Colombia: a qualitative study
Velosa J, Gómez J, Zúñiga C, Díaz G, Ferro B, Davis J, Grau L. Exploring stakeholders perspectives on TB contact investigation in Cali, Colombia: a qualitative study. Frontiers In Public Health 2023, 11: 1204862. PMID: 37564424, PMCID: PMC10411903, DOI: 10.3389/fpubh.2023.1204862.Peer-Reviewed Original ResearchConceptsTB contact investigationContact investigationPublic health staffHealth workersHousehold contactsTB knowledgeTB casesTest uptakeHealth staffHousehold visitsHealth OrganizationTuberculosis case findingNational public health authoritiesPublic health authoritiesWorld Health OrganizationPublic health organizationsMiddle-income countriesTB controlCase findingThematic analysisHealth authoritiesDiagnostic testsInductive thematic analysisSemi-structured interviewsMain barriersSex modifies the risk of HIV-associated obstructive lung disease in Ugandans postpneumonia
Abelman R, Fitzpatrick J, Zawedde J, Sanyu I, Byanyima P, Kaswabuli S, Musisi E, Hsieh J, Gardner K, Zhang M, Byanova K, Sessolo A, Hunt P, Lalitha R, Davis J, Crothers K, Worodria W, Huang L. Sex modifies the risk of HIV-associated obstructive lung disease in Ugandans postpneumonia. AIDS 2023, 37: 1683-1692. PMID: 37352494, PMCID: PMC10527596, DOI: 10.1097/qad.0000000000003626.Peer-Reviewed Original ResearchConceptsObstructive lung diseaseLung diseaseLung functionAbnormal lung functionMultivariable regression modelsWarrants further studyCommon comorbiditiesExpiratory volumeSpirometric abnormalitiesSmoking statusSpirometric testingTB statusVital capacitySex modifiesStratified analysisHIVWomenDiseaseComorbiditiesMenSexFurther studiesGreater degreeRiskTuberculosisFrequency of HIV serodifferent couples within TB-affected households in a setting with a high burden of HIV-associated TB
Anguzu G, Gupta A, Ochom E, Tseng A, Zhang M, Barnabas R, Flaxman A, Katamba A, Davis J, Ross J. Frequency of HIV serodifferent couples within TB-affected households in a setting with a high burden of HIV-associated TB. BMC Infectious Diseases 2023, 23: 388. PMID: 37296396, PMCID: PMC10251627, DOI: 10.1186/s12879-023-08365-y.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusUganda AIDS Indicator SurveyHIV prevention servicesIndex participantsContact investigationGeneral populationPrevention servicesFrequency of HIVProportion of HIVRisk of HIVSelf-reported HIV statusHIV testing resultsHIV-serodifferent couplesHousehold contact investigationTB contact investigationAIDS Indicator SurveyCross-sectional trialCommunity health workersIndex partnerSerodifferent couplesTB evaluationHousehold contactsHomes of participantsHIV statusImmunodeficiency virusDeep learning prediction of hospital readmissions for asthma and COPD
Lopez K, Li H, Lipkin-Moore Z, Kay S, Rajeevan H, Davis J, Wilson F, Rochester C, Gomez J. Deep learning prediction of hospital readmissions for asthma and COPD. Respiratory Research 2023, 24: 311. PMID: 38093373, PMCID: PMC10720134, DOI: 10.1186/s12931-023-02628-7.Peer-Reviewed Original Research
2022
“I can’t do it”: A qualitative study exploring case and contact experiences with COVID-19 contact tracing
Shelby T, Arechiga C, Gupta AJ, Hennein R, Schenck C, Weeks B, Bond M, Niccolai L, Davis JL, Grau LE. “I can’t do it”: A qualitative study exploring case and contact experiences with COVID-19 contact tracing. BMC Public Health 2022, 22: 1963. PMID: 36284292, PMCID: PMC9595089, DOI: 10.1186/s12889-022-14265-8.Peer-Reviewed Original ResearchConceptsContact experiencesBehaviour Change Wheel frameworkEmotional needsShape behaviorSocial contactPhysical symptomsSocial factorsLow trustPotential interventionsMotivationEngagementConvenience sampleCandidate interventionsBehavior modelQualitative studyExperienceEmotionsTrustWheel frameworkInterventionSymptomsFeasibility and Sensitivity of Saliva GeneXpert MTB/RIF Ultra for Tuberculosis Diagnosis in Adults in Uganda
Byanyima P, Kaswabuli S, Musisi E, Nabakiibi C, Zawedde J, Sanyu I, Sessolo A, Andama A, Worodria W, Huang L, Davis JL. Feasibility and Sensitivity of Saliva GeneXpert MTB/RIF Ultra for Tuberculosis Diagnosis in Adults in Uganda. Microbiology Spectrum 2022, 10: e00860-22. PMID: 36154664, PMCID: PMC9603304, DOI: 10.1128/spectrum.00860-22.Peer-Reviewed Original ResearchConceptsGeneXpert MTB/RIF UltraMTB/RIF UltraXpert UltraTB diagnosisMolecular testingHigh TB burden settingsCulture-confirmed TB casesSaliva samplesTB diagnostic evaluationActive tuberculosis diseaseProspective observational studyActive TB diagnosisCause of morbidityAcid-fast bacilliComposite reference standardReference standardCase-only studySingle saliva sampleWorld Health OrganizationSpot sputumTB evaluationConsecutive adultsTB casesBurden settingsOutpatient departmentCentering Health Equity Within COVID-19 Contact Tracing: Connecticut's Community Outreach Specialist Program
Johnson K, Diallo K, Hennein R, Shelby T, Zhou X, Gupta AJ, Ludomirsky A, Weiss JM, Nunez-Smith M, Soto K, Davis JL. Centering Health Equity Within COVID-19 Contact Tracing: Connecticut's Community Outreach Specialist Program. Journal Of Public Health Management And Practice 2022, 28: 728-738. PMID: 36194817, PMCID: PMC9560910, DOI: 10.1097/phh.0000000000001608.Peer-Reviewed Original ResearchConceptsNon-English speaking populationsRelevant language skillsLanguage skillsCultural barriersCompetent careField notesContact tracingLanguageCommunication effortsTarget communityCOVID-19-related stigmaMaterial supportSpecialist programLocal health departmentsQualitative analysisLow socioeconomic statusCross-sectional analysisCommunity-engaged strategiesProportion of residentsSpeakingCOVID-19 contactHealth departmentsCommunityHealth equityCOVID-19 educationAssessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia
Saranjav A, Parisi C, Zhou X, Dorjnamjil K, Samdan T, Erdenebaatar S, Chuluun A, Dalkh T, Ganbaatar G, Brooks MB, Spiegelman D, Ganmaa D, Davis JL. Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia. BMJ Open 2022, 12: e061229. PMID: 35973702, PMCID: PMC9386240, DOI: 10.1136/bmjopen-2022-061229.Peer-Reviewed Original ResearchConceptsPrimary health centersTB preventive therapyRoutine surveillance dataHealth centersHousehold contactsCohort studyPreventive therapyTB careTB dispensariesRetrospective cross-sectional cohort studyCross-sectional cohort studySurveillance dataActive TB treatmentGuideline-adherent careHealth system predictorsQuality of tuberculosisOdds of patientsHealth system factorsQuality improvement interventionsLow-quality careCare cascadeTB screeningTB treatmentTuberculosis careIndex patientsAssessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial
Armstrong-Hough M, Ggita J, Gupta AJ, Shelby T, Nangendo J, Ayen DO, Davis JL, Katamba A. Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial. BMJ Open 2022, 12: e061508. PMID: 35613785, PMCID: PMC9134160, DOI: 10.1136/bmjopen-2022-061508.Peer-Reviewed Original ResearchConceptsCommunity health workersHIV testingHIV test uptakeHIV status awarenessHome HIV testingHousehold contactsContact investigationTB stigmaTest uptakeHIV stigmaPublic Health Institutional Review BoardHealth Institutional Review BoardTB contact investigationTuberculosis contact investigationCluster-randomised trialHousehold tuberculosis contact investigationPublic health facilitiesVerbal informed consentHuman Investigation CommitteeMakerere University SchoolInstitutional review boardUganda National CouncilProportion of contactsHome HIVStatus awarenessCost-effectiveness analysis of human-centred design for global health interventions: a quantitative framework
Liu C, Lee J, Gupta A, Tucker A, Larkin C, Turimumahoro P, Katamba A, Davis J, Dowdy D. Cost-effectiveness analysis of human-centred design for global health interventions: a quantitative framework. BMJ Global Health 2022, 7: e007912. PMID: 35346954, PMCID: PMC8961136, DOI: 10.1136/bmjgh-2021-007912.Peer-Reviewed Original ResearchConceptsCost-effectiveness analysisLong-term costsUp-front costsQuantitative frameworkCost scenariosIntervention costsLarge initial costGlobal health interventionsHealth interventionsCostContact investigationInitial costHealth benefitsTB contact investigationTuberculosis contact investigationPayWillingnessHealth systemFrameworkNumber of clientsDALYsBenefitsUgandaInterventionGlobal health
2021
Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis
Cattamanchi A, Reza T, Nalugwa T, Adams K, Nantale M, Oyuku D, Nabwire S, Babirye D, Turyahabwe S, Tucker A, Sohn H, Ferguson O, Thompson R, Shete P, Handley M, Ackerman S, Joloba M, Moore D, Davis J, Dowdy D, Fielding K, Katamba A. Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis. New England Journal Of Medicine 2021, 385: 2441-2450. PMID: 34936740, PMCID: PMC9212879, DOI: 10.1056/nejmoa2105470.Peer-Reviewed Original ResearchConceptsSame-day treatmentSame-day diagnosisHealth centersMolecular testingTuberculosis testingHuman immunodeficiency virus (HIV) infectionDiagnostic strategiesImmunodeficiency virus infectionCommunity health centersCluster-randomized trialTreatment of tuberculosisSecondary outcomesMore patientsPrimary outcomePrompt diagnosisRoutine careEligible adultsIntervention groupIntervention periodHigh burdenVirus infectionIntervention centersControl groupPatientsTuberculosisEvaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study.
Diaz G, Victoria AM, Meyer AJ, Niño Y, Luna L, Ferro BE, Davis J. Evaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study. American Journal Of Tropical Medicine And Hygiene 2021, 104: 1309-1316. PMID: 33617470, PMCID: PMC8045602, DOI: 10.4269/ajtmh.20-0809.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyTuberculosis contact investigationContact investigationTB patientsHousehold visitsTB evaluationClinic visitsCohort studyEarly TB diagnosisIndex TB patientsTB contact investigationActive TB patientsTherapy initiationPreventive therapyTB diagnosisSymptomatic contactsMultivariable modelClinic referralsIndex patientsPatientsContact tracingVisitsCumulative probabilityLittle dataReferral
2018
Feasibility, Acceptability, and Adoption of Digital Fingerprinting During Contact Investigation for Tuberculosis in Kampala, Uganda: A Parallel-Convergent Mixed-Methods Analysis
White EB, Meyer AJ, Ggita JM, Babirye D, Mark D, Ayakaka I, Haberer JE, Katamba A, Armstrong-Hough M, Davis JL. Feasibility, Acceptability, and Adoption of Digital Fingerprinting During Contact Investigation for Tuberculosis in Kampala, Uganda: A Parallel-Convergent Mixed-Methods Analysis. Journal Of Medical Internet Research 2018, 20: e11541. PMID: 30442637, PMCID: PMC6265600, DOI: 10.2196/11541.Peer-Reviewed Original ResearchConceptsTechnology Acceptance Model 2Digital fingerprintingDigital fingerprintUnique patient identificationData integrityFingerprint captureSoftware leadFingerprint scannerPatient identificationHardware failureDigital technologiesBiometricsModest clusteringClusteringSocial imageTechnologyHousehold tuberculosis contact investigationRobust covariance estimatorPotential solutionsActual useGuide improvementFrameworkHardwareIndividual identificationTemporal characteristicsAssociation of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital
Chaisson LH, Duong D, Cattamanchi A, Roemer M, Handley MA, Schillinger D, Sur M, Pham P, Lin MA, Goldman LE, Quan J, Perez S, Healy M, Higashi J, Winston L, Haller B, Luetkemeyer AF, Davis JL. Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital. JAMA Internal Medicine 2018, 178: 1380-1388. PMID: 30178007, PMCID: PMC6368387, DOI: 10.1001/jamainternmed.2018.3638.Peer-Reviewed Original ResearchConceptsDiscontinuation of isolationMolecular testing algorithmRespiratory isolationMolecular testingPossible tuberculosisActive tuberculosisPreimplementation periodUS hospitalsZuckerberg San Francisco General HospitalSan Francisco General HospitalGeneXpert MTB/RIFCulture-confirmed tuberculosisPatient-centered evaluationActive pulmonary tuberculosisProportion of patientsProspective cohort studyLength of stayMTB/RIFRapid test resultsRapid molecular testingSputum smear microscopyMolecular testing strategiesHealth care settingsCulture-negative resultsTB-negative patientsPatterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda
Ggita JM, Ojok C, Meyer AJ, Farr K, Shete PB, Ochom E, Turimumahoro P, Babirye D, Mark D, Dowdy D, Ackerman S, Armstrong-Hough M, Nalugwa T, Ayakaka I, Moore D, Haberer JE, Cattamanchi A, Katamba A, Davis JL. Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 530-536. PMID: 29663958, PMCID: PMC6350252, DOI: 10.5588/ijtld.17.0521.Peer-Reviewed Original ResearchConceptsClinic attendeesHousehold contactsTB patientsClinic visitsClinic patientsMHealth interventionsTuberculosisMobile phone accessHealth communicationPatientsUrban KampalaMost contactPhone accessPhone sharingLittle informationAttendeesText messagesPatterns of usageShort messaging service (SMS) messagesUgandaCentral UgandaVisitsRecipientsThe impact of digital health technologies on tuberculosis treatment: a systematic review
Ngwatu B, Nsengiyumva N, Oxlade O, Mappin-Kasirer B, Nguyen N, Jaramillo E, Falzon D, Schwartzman K, Abubakar I, Alipanah N, Bastos M, Boccia D, Chin D, Cohen T, Davis J, Denkinger C, Falzon D, Fielding K, Fox G, Free C, Garfein R, Hayward A, Jaramillo E, Lester R, Lewis J, Mappin-Kasirer B, Marx F, Menzies D, Migliori G, Nahid P, Ngwatu B, Nsengiyumva N, Nguyen N, Oxlade O, Schwartzman K, Siddiqi K, Story A, Thomas B, Trajman A, Yassin M. The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal 2018, 51: 1701596. PMID: 29326332, PMCID: PMC5764088, DOI: 10.1183/13993003.01596-2017.Peer-Reviewed Original ResearchConceptsVideo-observed therapyMedication monitorsStandard careObservational studyTreatment completion ratesTB treatment adherenceProbability of cureTreatment of personsPerson DOTActive tuberculosisTB careClinical outcomesTreatment adherenceTuberculosis treatmentPatient outcomesTreatment completionControl groupTreatment dosesSystematic reviewDigital health technologiesShort message serviceEffect estimatesTuberculosisDigital interventionsCare
2017
Bringing patient-centered tuberculosis diagnosis into the light of day
Davis JL. Bringing patient-centered tuberculosis diagnosis into the light of day. BMC Medicine 2017, 15: 219. PMID: 29258526, PMCID: PMC5738029, DOI: 10.1186/s12916-017-0992-4.Peer-Reviewed Original ResearchConceptsSmear microscopySame-day sputum smear microscopyTB diagnostic toolsPatient-centered TB careEnd TB Strategy goalsPatient-centered careSputum smear microscopyPatient-centered servicesTuberculosis deathsTB careTB StrategyTuberculosis diagnosisDiagnostic careCatastrophic costsRecent evidenceCareDiagnostic toolRelated articles