2024
Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
2023
Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients
Junn A, Long A, Hauc S, Almeida M, Alper D, Rivera J, Mayes L, Persing J, Alperovich M. Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients. Child's Nervous System 2023, 39: 1921-1928. PMID: 36877207, DOI: 10.1007/s00381-023-05908-1.Peer-Reviewed Original ResearchConceptsFull Scale IQVisuomotor integrationVisual perceptionVerbal IQNeurocognitive testingVisual perception scoresHigher scoresLong-term neurocognitive outcomesCognitive profileWhite matter connectionsNeurocognitive deficitsIQPerception scoresMean IQNeurocognitive outcomesFrontal lobeLower scoresMotor controlMotor coordinationPerceptionNon-syndromic craniosynostosisUnicoronal synostosisScoresChildren 6
2022
Quantitative MRI Characterization of the Extremely Preterm Brain at Adolescence: Atypical versus Neurotypical Developmental Pathways
McNaughton R, Pieper C, Sakai O, Rollins J, Zhang X, Kennedy D, Frazier J, Douglass L, Heeren T, Fry R, O'Shea T, Kuban K, Jara H, Rollins J, Shah B, Singh R, Vaidya R, Van Marter L, Martin C, Ware J, Rollins C, Cole C, Perrin E, Sakai C, Bednarek F, Frazier J, Ehrenkranz R, Benjamin J, Montgomery A, O'Shea T, Washburn L, Gogcu S, Bose C, Warner D, O'Shea T, Engelke S, Higginson A, Higginson J, Bear K, Poortenga M, Pastyrnak S, Karna P, Paneth N, Lenski M, Schreiber M, Hunter S, Msall M, Batton D, Klarr J, Lee Y, Obeid R, Christianson K, Klein D, Wagner K, Pimental M, Hallisey C, Coster T, Dolins M, Mittleman M, Haile H, Rohde J, Nylen E, Neger E, Mattern K, Ma C, Toner D, Vitaro E, Venuti L, Powers B, Foley A, Sacco T, Williams J, Romano E, Henry C, Hiatt D, Peters N, Brown P, Ansusinha E, Smith J, Yang N, Bose G, Wereszczak J, Bernhardt J, Adams J, Wilson D, Darden-Saad N, Williams B, Jones E, Sutton D, Rathbun J, Fagerman S, Boshoven W, Johnson J, James B, Miras K, Solomon C, Weiland D, Yoon G, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Lynch E, Kring B, Smith A, McQuiston S, Butler S, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Henson B, Keller C, Walkowiak J, Barron S, Miller A, Dessureau B, Wood M, Damon-Minow J, Romano E, Mayes L, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Waldrep E, Friedman J, Hounshell G, Allred D, Helms R, Whitley L, Stainback G, Bostic L, Jacobson A, McKeeman J, Meyer E, Price J, Lloyd M, Plesha-Troyke S, Scott M, Solomon K, Brooklier K, Vogt K. Quantitative MRI Characterization of the Extremely Preterm Brain at Adolescence: Atypical versus Neurotypical Developmental Pathways. Radiology 2022, 304: 419-428. PMID: 35471112, PMCID: PMC9340244, DOI: 10.1148/radiol.210385.Peer-Reviewed Original ResearchConceptsWhite matterPerinatal white matter injuryExtremely preterm birthsProspective multicenter studyWhite matter injuryPreterm birthCerebral palsyMRI evaluationMulticenter studyClinical correlatesNeurocognitive outcomesHigh riskCerebrospinal fluidQuantitative MRI parametersCognitive impairmentMRI biomarkersGray matterMRI parametersCSF volumeBrain developmentModerate negative associationAdolescentsBoysGirlsAutism spectrum disorder
1999
Developing brain and in utero cocaine exposure: Effects on neural ontogeny
MAYES L. Developing brain and in utero cocaine exposure: Effects on neural ontogeny. Development And Psychopathology 1999, 11: 685-714. PMID: 10624721, DOI: 10.1017/s0954579499002278.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureCocaine exposureNeural ontogenyNervous system ontogenyUtero cocaine exposureCNS ontogenyType of exposureMonoaminergic systemsMonoamine systemsPreclinical studiesCocaine effectsNeuropsychological effectsNervous systemPatterns of arousalPrimary siteNeural migrationCell proliferationYoung childrenTrophic roleCocaine-related effectsExposureBrainAttention regulationCandidate mechanismArousal
1998
Regulation of arousal and attention in preschool children exposed to cocaine prenatally.
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of arousal and attention in preschool children exposed to cocaine prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-43. PMID: 9668402.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effectsRegulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally
Mayes L, Grillon C, Granger R, Schottenfeld R. Regulation of Arousal and Attention in Preschool Children Exposed to Cocaine Prenatally. Annals Of The New York Academy Of Sciences 1998, 846: 126-143. PMID: 29087549, DOI: 10.1111/j.1749-6632.1998.tb09731.x.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureArousal regulationRegulation of arousalCocaine exposureAged childrenCocaine-exposed childrenFace of noveltyOngoing information processingSubstance-abusing familiesAttention regulationCocaine-exposed infantsEmotional reactivityImpaired attentionStructured tasksNeurobehavioral findingsStressful situationsInformation processingHuman infantsNeurophysiological findingsPreschool childrenArousalSuch childrenStartle responseStress circuitsNeurobehavioral effects