Adrenocorticotropic hormone and cortisol response to corticotropin releasing hormone in the critically ill—a novel assessment of the hypothalamic-pituitary-adrenal axis
Schuster KM, Macleod JB, Fernandez JB, Kumar M, Barquist ES. Adrenocorticotropic hormone and cortisol response to corticotropin releasing hormone in the critically ill—a novel assessment of the hypothalamic-pituitary-adrenal axis. The American Journal Of Surgery 2011, 203: 205-210. PMID: 21679920, DOI: 10.1016/j.amjsurg.2010.11.015.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal InsufficiencyAdrenocorticotropic HormoneAgedAged, 80 and overArea Under CurveCorticotropin-Releasing HormoneCosyntropinCritical IllnessFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemIntensive Care UnitsLinear ModelsMaleMiddle AgedPituitary-Adrenal SystemPostoperative ComplicationsPrognosisConceptsCorticotropin-releasing hormoneAdrenocorticotropic hormoneSurgical intensive care unitCosyntropin stimulation testIntensive care unitAdrenal insufficiencyCRH administrationACTH responseAdrenal functionCare unitStimulation testingAdrenal axisStimulation testACTH peakACTH responsivenessCortisol peakCortisol responseNormal responsePatientsChi-squareHormoneCortisolNonsurvivorsT-testP-value