2024
Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study
Estroff J, Devlin J, Hoteit L, Hassoune A, Neal M, Brown J, Lu L, Kotch S, Hazelton J, Christian A, Yeates E, Nahmias J, Jacobson L, Williams J, Schuster K, O'Connor R, Semon G, Straughn A, Cullinane D, Egodage T, Kincaid M, Rollins A, Amdur R, Sarani B. Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 97: 541-545. PMID: 38685190, DOI: 10.1097/ta.0000000000004345.Peer-Reviewed Original ResearchProthrombin complex concentrateAmount of RBC transfusionRed blood cell transfusionAndexanet alfaRed blood cellsRBC transfusionMulticenter study of adult patientsNon-inferiorityComparing prothrombin complex concentrateOral factor Xa inhibitorsStudy of adult patientsTransfused red blood cellsIncreased RBC transfusionsReversal of DOACsComplex concentrateFactor Xa inhibitorsTreatment of hemorrhageTraumatically injured patientsDOAC reversalMedian transfusionTransfusion rateUnit transfusionsMulticenter studyAdult patientsXa inhibitors
2023
Alcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File
Jones T, Bhattacharya B, Schuster K, Becher R, Kodadek L, Davis K, Maung A. Alcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File. Trauma Surgery & Acute Care Open 2023, 8: e001047. PMID: 37188153, PMCID: PMC10175962, DOI: 10.1136/tsaco-2022-001047.Peer-Reviewed Original ResearchAlcohol withdrawal syndromeAlcohol use disorderPositive blood alcohol concentrationHistory of AUDBlood alcohol concentrationParticipant User FileAdult patientsTrauma patientsWithdrawal syndromeAbbreviated Injury Scale headHigh-risk patient populationInjury scale headAdult trauma patientsPositive toxicology screenMultivariable logistic regressionRetrospective reviewRetrospective studyToxicology screenPatient populationTricyclic antidepressantsMAIN OUTCOMEAmerican CollegePatientsUse disordersUncommon occurrence
2022
Occult traumatic pneumothorax: Is routine follow up chest X-ray necessary?
Bhattacharya B, O'Connor R, Becher R, Schuster K, Davis K, Maung A. Occult traumatic pneumothorax: Is routine follow up chest X-ray necessary? Surgery In Practice And Science 2022, 9: 100073. DOI: 10.1016/j.sipas.2022.100073.Peer-Reviewed Original ResearchChest X-rayRoutine chest X-rayInjury Severity ScoreClinical managementInitial trauma evaluationUrban trauma centerComputerized tomography scanPaucity of evidenceOccult pneumothoracesPneumothorax progressionAdult patientsTrauma centerClinical evolutionClinical symptomsInjury scoreMean ageTrauma evaluationSeverity scoreTomography scanPatientsInterventionPneumothoracesSymptomsAgeX-ray
2019
Regionalization of emergency general surgery operations: A simulation study.
Becher RD, Sukumar N, DeWane MP, Gill TM, Maung AA, Schuster KM, Stolar MJ, Davis KA. Regionalization of emergency general surgery operations: A simulation study. Journal Of Trauma And Acute Care Surgery 2019, 88: 366-371. PMID: 31804419, PMCID: PMC7472889, DOI: 10.1097/ta.0000000000002543.Peer-Reviewed Original ResearchConceptsEmergency general surgeryHigh-volume hospitalsEGS careEmergency general surgery operationsCalifornia inpatient databaseCommon EGS operationsRisk-adjusted deathsSignificant survival benefitLow-volume hospitalsUmbilical hernia repairSmall bowel resectionHigh-mortality hospitalsGeneral surgery operationsRegional trauma systemEGS operationsBowel resectionAdult patientsPrimary outcomeSurvival benefitInpatient DatabaseHernia repairTrauma systemLevel IVGeneral surgeryCare managementTop-tier emergency general surgery hospitals: Good at one operation, good at them all.
DeWane MP, Sukumar N, Stolar MJ, Gill TM, Maung AA, Schuster KM, Davis KA, Becher RD. Top-tier emergency general surgery hospitals: Good at one operation, good at them all. Journal Of Trauma And Acute Care Surgery 2019, 87: 289-296. PMID: 31349347, PMCID: PMC6771423, DOI: 10.1097/ta.0000000000002367.Peer-Reviewed Original ResearchConceptsRisk-adjusted mortalityEGS hospitalsHospital risk-adjusted mortalityOperation typeEGS operationsCalifornia State Inpatient DatabaseGeneral surgery hospitalsHospital-level factorsAcute care hospitalsState Inpatient DatabasesAmerican Hospital Association databasePoor-performing hospitalsSystems of careLow-risk operationAssessment of mortalityAdult patientsCare hospitalSurgery HospitalInpatient DatabaseHospital characteristicsMultinomial logistic regressionMortality rateHospitalLevel IIIZ-scoreHospital Volume and Operative Mortality for General Surgery Operations Performed Emergently in Adults
Becher RD, DeWane MP, Sukumar N, Stolar MJ, Gill TM, Maung AA, Schuster KM, Davis KA. Hospital Volume and Operative Mortality for General Surgery Operations Performed Emergently in Adults. Annals Of Surgery 2019, Publish Ahead of Print: &na;. PMID: 32675542, PMCID: PMC6803029, DOI: 10.1097/sla.0000000000003232.Peer-Reviewed Original ResearchHospital operative volumeSurgical emergencyAcute care hospitalsGeneral surgery operationsHospital volumeCare hospitalOperative volumeVolume thresholdEmergency general surgery operationsRetrospective cohort studyHigh-volume hospitalsUmbilical hernia repairRisk-adjusted mortalitySurgery operationsAverage mortality riskSurgical outcomes researchOperative mortalityAdult patientsCohort studyPublic health crisisHernia repairMortality riskTrauma surgerySurvival rateEmergency operation
2018
Opioid dependency is independently associated with inferior clinical outcomes after trauma
Hsiang WR, McGeoch C, Lee S, Cheung W, Becher R, Davis KA, Schuster K. Opioid dependency is independently associated with inferior clinical outcomes after trauma. Injury 2018, 50: 192-196. PMID: 30342762, DOI: 10.1016/j.injury.2018.10.015.Peer-Reviewed Original ResearchConceptsNon-home dischargeOpioid-dependent patientsLength of stayInjury Severity ScoreOpioid dependencyVentilator daysMajor complicationsClinical outcomesPrescription abuseIllicit abuseLonger LOSChronic pain subgroupsMore ventilator daysOpioid-naïve patientsUse of opioidsAcademic Level IHigher readmission ratesInferior clinical outcomesChronic pain patientsOpioid subgroupsNaïve patientsAdult patientsPain subgroupsPatient demographicsReadmission ratesTotal bilirubin trend as a predictor of common bile duct stones in acute cholecystitis and symptomatic cholelithiasis
Gillaspie DB, Davis KA, Schuster KM. Total bilirubin trend as a predictor of common bile duct stones in acute cholecystitis and symptomatic cholelithiasis. The American Journal Of Surgery 2018, 217: 98-102. PMID: 29929909, DOI: 10.1016/j.amjsurg.2018.06.011.Peer-Reviewed Original ResearchConceptsCommon bile duct stonesBile duct stonesAcute cholecystitisSymptomatic cholelithiasisDuct stonesBilirubin levelsProcedural interventionTotal bilirubinPresence of CBDSElevated total bilirubinTotal bilirubin levelsElevated serum bilirubinBiliary colicAdult patientsSerum bilirubinSerum makersImmediate imagingCholecystitisBilirubinCholelithiasisPatientsInterventionColicLevels
2013
Routine Nasogastric Decompression in Small Bowel Obstruction: Is it Really Necessary?
Fonseca AL, Schuster KM, Maung AA, Kaplan LJ, Davis KA. Routine Nasogastric Decompression in Small Bowel Obstruction: Is it Really Necessary? The American Surgeon 2013, 79: 422-428. PMID: 23574854, DOI: 10.1177/000313481307900433.Peer-Reviewed Original ResearchConceptsSmall bowel obstructionNasogastric decompressionHospital lengthNG decompressionBowel obstructionRespiratory failureDiagnosis of SBOYale-New Haven HospitalNasogastric tube useRisk of pneumoniaRoutine nasogastric decompressionDevelopment of pneumoniaRetrospective chart reviewNew Haven HospitalBowel restIntravenous hydrationChart reviewAdult patientsTube useNGT placementPatientsStayOutcome variablesDecompressionNGT