Methionine‐Restricted Diet Increases miRNAs That Can Target RUNX2 Expression and Alters Bone Structure in Young Mice
Plummer J, Park M, Perodin F, Horowitz MC, Hens JR. Methionine‐Restricted Diet Increases miRNAs That Can Target RUNX2 Expression and Alters Bone Structure in Young Mice. Journal Of Cellular Biochemistry 2016, 118: 31-42. PMID: 27191548, PMCID: PMC5426510, DOI: 10.1002/jcb.25604.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood GlucoseBone DensityCore Binding Factor Alpha 1 SubunitFibroblast Growth Factor-23Fibroblast Growth FactorsFood, FormulatedGene Expression RegulationMaleMethionineMiceMicroRNAsTibiaConceptsDietary methionine restrictionBone tissue densityMR miceMethionine restrictionBone marrowMale C57BL/6J miceBone-related biomarkersYoung male C57BL/6J miceBone structureMiR-335-5pPlasma levelsC57BL/6J micePlasma glucoseRodent modelsBone volumeFat depotsTrabecular thicknessFat accretionBone remodelingMiceBiomechanical testingMiR-204Reduced expressionMiR-31Significant decrease