2017
Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation
Friedmann D, Keller B, Harder I, Schupp J, Tanriver Y, Unger S, Warnatz K. Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation. Journal Of Clinical Immunology 2017, 37: 759-769. PMID: 28936778, DOI: 10.1007/s10875-017-0444-0.Peer-Reviewed Original ResearchConceptsInnate lymphoid cellsCommon variable immunodeficiencyTh1-like T cellsCD21low B cellsCVID patientsT cellsSecondary complicationsVariable immunodeficiencyILC phenotypesB cellsInnate lymphoid cells type 2T helper cell subsetsBroad immune dysregulationThird of patientsCD4 T cellsCell type 2Helper cell subsetsInflammatory organ diseaseAdaptive immune systemAutoimmune manifestationsImmune dysregulationTh1 shiftCell subsetsImmunological phenotypePeripheral blood
2016
Neue pathogenetische Konzepte und frühe pharmakologische Studien bei der Sarkoidose
Schupp J, Frye B, Zissel G, Müller-Quernheim J. Neue pathogenetische Konzepte und frühe pharmakologische Studien bei der Sarkoidose. Pneumologie 2016, 70: 231-240. PMID: 26937647, DOI: 10.1055/s-0041-108311.Commentaries, Editorials and LettersConceptsSarcoid patientsGranuloma formationSarcoidosis-associated fatigueClinical pharmacological studiesEtiology of sarcoidosisGenetics of sarcoidosisPulmonary hypertensionMycobacterial antigensAntigen presentationSarcoidosisPositive studiesClinical researchPatientsSubcohortAutoimmunityPositive outcomesNew studiesWide association studyAssociation studiesHypertensionAutoantigensPathomechanismEtiologyNew findingsStudy